| Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 M Thoms, R Buschauer, M Ameismeier, L Koepke, T Denk, ... Science 369 (6508), 1249-1255, 2020 | 758 | 2020 |
| SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas JA Müller, R Groß, C Conzelmann, J Krüger, U Merle, J Steinhart, T Weil, ... Nature metabolism 3 (2), 149-165, 2021 | 474 | 2021 |
| TRIM proteins and their roles in antiviral host defenses M van Gent, KMJ Sparrer, MU Gack Annual review of virology 5, 385-405, 2018 | 251 | 2018 |
| Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity JJ Chiang, KMJ Sparrer, M van Gent, C Lässig, T Huang, N Osterrieder, ... Nature immunology 19 (1), 53-62, 2018 | 210 | 2018 |
| Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities M Hayn, M Hirschenberger, L Koepke, R Nchioua, JH Straub, S Klute, ... Cell reports 35 (7), 2021 | 199 | 2021 |
| Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning? C Jung, D Kmiec, L Koepke, F Zech, T Jacob, KMJ Sparrer, F Kirchhoff Journal of virology 96 (6), e02077-21, 2022 | 172 | 2022 |
| TRIM23 mediates virus-induced autophagy via activation of TBK1 KMJ Sparrer, S Gableske, MA Zurenski, ZM Parker, F Full, GJ Baumgart, ... Nature microbiology 2 (11), 1543-1557, 2017 | 168 | 2017 |
| IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro C Prelli Bozzo, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, ... Nature communications 12 (1), 4584, 2021 | 166* | 2021 |
| In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells S Runge, KMJ Sparrer, C Lässig, K Hembach, A Baum, A García-Sastre, ... PLoS pathogens 10 (4), e1004081, 2014 | 162 | 2014 |
| Intracellular detection of viral nucleic acids KMJ Sparrer, MU Gack Current opinion in microbiology 26, 1-9, 2015 | 134 | 2015 |
| Mechanism of TRIM25 catalytic activation in the antiviral RIG-I pathway JG Sanchez, JJ Chiang, KMJ Sparrer, SL Alam, M Chi, MD Roganowicz, ... Cell reports 16 (5), 1315-1325, 2016 | 128 | 2016 |
| Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection L Wettstein, T Weil, C Conzelmann, JA Müller, R Groß, M Hirschenberger, ... Nature communications 12 (1), 1726, 2021 | 124* | 2021 |
| Guanylate-binding proteins 2 and 5 exert broad antiviral activity by inhibiting furin-mediated processing of viral envelope proteins E Braun, D Hotter, L Koepke, F Zech, R Groß, KMJ Sparrer, JA Müller, ... Cell reports 27 (7), 2092-2104. e10, 2019 | 123 | 2019 |
| SARS-CoV-2 is restricted by zinc finger antiviral protein despite preadaptation to the low-CpG environment in humans R Nchioua, D Kmiec, JA Müller, C Conzelmann, R Groß, CM Swanson, ... MBio 11 (5), 10.1128/mbio. 01930-20, 2020 | 121* | 2020 |
| ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA C Lässig, S Matheisl, KMJ Sparrer, CC de Oliveira Mann, M Moldt, ... Elife 4, e10859, 2015 | 105 | 2015 |
| Drug inhibition of SARS-CoV-2 replication in human pluripotent stem cell–derived intestinal organoids J Krüger, R Groß, C Conzelmann, JA Müller, L Koepke, KMJ Sparrer, ... Cellular and Molecular Gastroenterology and Hepatology 11 (4), 935-948, 2021 | 93* | 2021 |
| Click-modified anandamide siRNA enables delivery and gene silencing in neuronal and immune cells J Willibald, J Harder, K Sparrer, KK Conzelmann, T Carell Journal of the American Chemical Society 134 (30), 12330-12333, 2012 | 93 | 2012 |
| Measles virus C protein interferes with Beta interferon transcription in the nucleus KMJ Sparrer, CK Pfaller, KK Conzelmann Journal of virology 86 (2), 796-805, 2012 | 81 | 2012 |
| Manipulation of autophagy by SARS-CoV-2 proteins L Koepke, M Hirschenberger, M Hayn, F Kirchhoff, KMJ Sparrer Autophagy 17 (9), 2659-2661, 2021 | 71 | 2021 |
| TRIM25 binds RNA to modulate cellular anti-viral defense JG Sanchez, KMJ Sparrer, C Chiang, RA Reis, JJ Chiang, MA Zurenski, ... Journal of molecular biology 430 (24), 5280-5293, 2018 | 71 | 2018 |
