Comparison of the binding of reversible inhibitors to human butyrylcholinesterase and acetylcholinesterase: A crystallographic, kinetic and calorimetric study TL Rosenberry, X Brazzolotto, IR Macdonald, M Wandhammer, ... Molecules 22 (12), 2098, 2017 | 222 | 2017 |
Early detection of cerebral glucose uptake changes in the 5XFAD mouse IR Macdonald, DR DeBay, GA Reid, TP O’leary, CT Jollymore, G Mawko, ... Current Alzheimer Research 11 (5), 450-460, 2014 | 85 | 2014 |
Cholinesterase inhibition in Alzheimer's disease: is specificity the answer? IR Macdonald, K Rockwood, E Martin, S Darvesh Journal of Alzheimer's Disease 42 (2), 379-384, 2014 | 85 | 2014 |
Quantification of butyrylcholinesterase activity as a sensitive and specific biomarker of Alzheimer’s disease IR Macdonald, SP Maxwell, GA Reid, MK Cash, DR DeBay, S Darvesh Journal of Alzheimer's Disease 58 (2), 491-505, 2017 | 78 | 2017 |
Probing the peripheral site of human butyrylcholinesterase IR Macdonald, E Martin, TL Rosenberry, S Darvesh Biochemistry 51 (36), 7046-7053, 2012 | 71 | 2012 |
Butyrylcholinesterase activity in multiple sclerosis neuropathology S Darvesh, AM LeBlanc, IR Macdonald, GA Reid, V Bhan, RJ Macaulay, ... Chemico-biological interactions 187 (1-3), 425-431, 2010 | 55 | 2010 |
Butyrylcholinesterase-knockout reduces fibrillar β-amyloid and conserves 18FDG retention in 5XFAD mouse model of Alzheimer’s disease DR DeBay, GA Reid, IR Macdonald, G Mawko, S Burrell, E Martin, ... Brain research 1671, 102-110, 2017 | 36 | 2017 |
Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems S Darvesh, IR Macdonald, E Martin Bioorganic & medicinal chemistry letters 23 (13), 3822-3825, 2013 | 22 | 2013 |
Synthesis and preliminary evaluation of phenyl 4-123I-iodophenylcarbamate for visualization of cholinesterases associated with Alzheimer disease pathology IR Macdonald, GA Reid, IR Pottie, E Martin, S Darvesh Journal of Nuclear Medicine 57 (2), 297-302, 2016 | 15 | 2016 |
Cysteine thioesters as myelin proteolipid protein analogues to examine the role of butyrylcholinesterase in myelin decompaction IR Pottie, EA Higgins, RA Blackman, IR Macdonald, E Martin, S Darvesh ACS Chemical Neuroscience 2 (3), 151-159, 2011 | 15 | 2011 |
Delayed parent artery occlusions following use of Silk flow diverters for treatment of intracranial aneurysms IR Macdonald, JJS Shankar Journal of NeuroInterventional Surgery 11 (7), 690-693, 2019 | 11 | 2019 |
Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase IR Macdonald, GA Reid, EE Joy, IR Pottie, G Matte, S Burrell, G Mawko, ... Molecular imaging and biology 13, 1250-1261, 2011 | 10 | 2011 |
Thioesters for the in vitro evaluation of agents to image brain cholinesterases IR Macdonald, CT Jollymore, GA Reid, IR Pottie, E Martin, S Darvesh Journal of Enzyme Inhibition and Medicinal Chemistry 28 (3), 447-455, 2013 | 4 | 2013 |
Standardized approach to direct first pass aspiration technique for endovascular thrombectomy: Description and initial experience with CANADAPT IR Macdonald, V Linehan, B Sneek, D Volders Interventional Neuroradiology, 15910199241230360, 2024 | 2 | 2024 |
Practical use and underlying physics of the BENCHMARK™ BMX™ 96 for large-bore aspiration thrombectomy: Case report of initial institutional experience IR Macdonald, EA Cora, I Grant, D Volders The Neuroradiology Journal 35 (2), 250-254, 2022 | 2 | 2022 |
Butyrylcholinesterase ligands as diagnostic tools and treatment for diseases of the nervous system S Darvesh, E Joy, E Martin, I MacDonald, I Pottie US Patent 8,795,630, 2014 | 1 | 2014 |
IC-P-045 CEREBRAL GLUCOSE METABOLISM, PATHOLOGY AND BEHAVIOR IN THE 5XFAD MOUSE MODEL OF ALZHEIMER’S DISEASE I Macdonald, A Reid, I Pottie, E Martin, S Darvesh Alzheimer's & Dementia 9, P32-P32, 2013 | 1 | 2013 |
IC-P-051 SYNTHESIS AND EVALUATION OF BUTYRYLCHOLINESTERASE LIGANDS FOR NEUROIMAGING ALZHEIMER’S DISEASE I Macdonald, I Pottie, EE Joy, G Matte, S Burrell, G Mawko, E Martin, ... Alzheimer's & Dementia 6, S23-S23, 2010 | 1 | 2010 |
The importance of arterial systolic pressure (Push) in successful first pass aspiration technique for endovascular thrombectomy. D Volders, V Linehan, IR Macdonald Journal of Neuroradiology= Journal de Neuroradiologie, S0150-9861 (24) 00123, 2024 | | 2024 |
Evaluation of Patients with Cranial Nerve Disorders JW Casselman, A Krainik, I Macdonald Diseases of the Brain, Head and Neck, Spine 2024-2027: Diagnostic Imaging …, 2024 | | 2024 |