| Improved low molecular weight Myc-Max inhibitors H Wang, DI Hammoudeh, AV Follis, BE Reese, JS Lazo, SJ Metallo, ... Molecular cancer therapeutics 6 (9), 2399-2408, 2007 | 249 | 2007 |
| Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc DI Hammoudeh, AV Follis, EV Prochownik, SJ Metallo Journal of the American Chemical Society 131 (21), 7390-7401, 2009 | 247 | 2009 |
| Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules AV Follis, DI Hammoudeh, H Wang, EV Prochownik, SJ Metallo Chemistry & biology 15 (11), 1149-1155, 2008 | 199 | 2008 |
| Discovery of novel Myc− Max heterodimer disruptors with a three-dimensional pharmacophore model G Mustata, AV Follis, DI Hammoudeh, SJ Metallo, H Wang, ... Journal of medicinal chemistry 52 (5), 1247-1250, 2009 | 103 | 2009 |
| Small-molecule perturbation of competing interactions between c-Myc and Max AV Follis, DI Hammoudeh, AT Daab, SJ Metallo Bioorganic & medicinal chemistry letters 19 (3), 807-810, 2009 | 71 | 2009 |
| Replacing sulfa drugs with novel DHPS inhibitors DI Hammoudeh, Y Zhao, SW White, RE Lee Future medicinal chemistry 5 (11), 1331-1340, 2013 | 58 | 2013 |
| Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase DI Hammoudeh, M Daté, MK Yun, W Zhang, VA Boyd, A Viacava Follis, ... ACS Chemical Biology 9 (6), 1294-1302, 2014 | 34 | 2014 |
| Structure‐Based Design of Novel Pyrimido[4,5‐c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity Y Zhao, D Hammoudeh, MK Yun, J Qi, SW White, RE Lee ChemMedChem 7 (5), 861-870, 2012 | 34 | 2012 |
| Development of a pterin-based fluorescent probe for screening dihydropteroate synthase Y Zhao, D Hammoudeh, W Lin, S Das, MK Yun, Z Li, E Griffith, T Chen, ... Bioconjugate Chemistry 22 (10), 2110-2117, 2011 | 11 | 2011 |
| Structure‐Based Design of AG‐946, a Pyruvate Kinase Activator T Liu, AK Padyana, ET Judd, L Jin, D Hammoudeh, C Kung, L Dang ChemMedChem 19 (5), e202300559, 2024 | | 2024 |
| Fragment-Based Approach Identifies a Novel Inhibitory Site on DHPS D Hammoudeh, MK Yun, AV Follis, Y Zhao, B Waddell, RE Lee, S White Biophysical Journal 104 (2), 403a, 2013 | | 2013 |
| Mechanism of Small-Molecule Binding by Intrinsically Disordered Proteins SJ Metallo, AV Follis, DI Hammoudeh, EV Prochownik Biophysical Journal 98 (3), 259a, 2010 | | 2010 |
| Small molecule binding of intrinsically disordered proteins: Multiple binders on multiple sites D Hammoudeh, A Viachava-Follis, EV Prochownik, SJ Metallo Biophysical Journal 96 (3), 319a, 2009 | | 2009 |
| Potent Inhibitors Of c-Myc-Max Dimerization Through Multivalent Binding To The Intrinsically Disordered c-Myc Monomer AV Follis, D Hammoudeh, H Wang, EV Prochownik, SJ Metallo Biophysical Journal 96 (3), 443a, 2009 | | 2009 |
| Mode of action of a small molecule inhibitor of c‐Myc: finding of a sequence‐defined binding site on an intrinsically disordered protein AV Follis, D Hammoudeh, H Wang, EV Prochownik, SJ Metallo The FASEB Journal 21 (6), LB18-LB18, 2007 | | 2007 |
| Interactions between small molecules and an intrinsically disordered protein: small molecule inhibitors of the oncogenic transcription factor c‐Myc D Hammoudeh, A Viacava‐Follis, H Wang, EV Prochownik, SJ Metallo The FASEB Journal 21 (6), LB18-LB18, 2007 | | 2007 |
| Small molecule inhibitors of Myc-Max interactions D Hammoudeh, AGV Follis, SJ Metallo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U570-U570, 2005 | | 2005 |
| The ACE inhibitor drugs allow for increased levels of bradykinin which would normally be degraded. Menu AV Follis, DI Hammoudeh, H Wang, EV Prochownik, SJ Metallo | | |
| Discovery of Novel Myc-Max Heterodimer Disruptors with a 3-Dimensional Pharmacophore Model G Mustata, AV Follis, DI Hammoudeh, SJ Metallo, H Wang, ... | | |
| Tuesday, March 3, 2009 443a AV Follis, D Hammoudeh, H Wang, EV Prochownik, SJ Metallo | | |
Ariele Viacava FollisDirector of Structural Biology, Rome TherapeuticsVerified email at rometx.com
