| Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system MG Varga, CL Shaffer, JC Sierra, G Suarez, MB Piazuelo, ME Whitaker, ... Oncogene 35 (48), 6262-6269, 2016 | 118 | 2016 |
| Adhesive Fiber Stratification in Uropathogenic Escherichia coli Biofilms Unveils Oxygen-Mediated Control of Type 1 Pili KA Floyd, JL Moore, AR Eberly, JAD Good, CL Shaffer, H Zaver, ... PLoS Pathogens 11 (3), 2015 | 99 | 2015 |
| Triphenylbutanamines: kinesin spindle protein inhibitors with in vivo antitumor activity F Wang, JAD Good, O Rath, HYK Kaan, OB Sutcliffe, SP Mackay, ... Journal of Medicinal Chemistry 55 (4), 1511-1525, 2012 | 74 | 2012 |
| Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis K Flentie, GA Harrison, H Tükenmez, J Livny, JAD Good, S Sarkar, ... Proceedings of the National Academy of Sciences 116 (21), 10510-10517, 2019 | 55 | 2019 |
| Thiazolino 2-pyridone amide inhibitors of Chlamydia trachomatis infectivity JAD Good, J Silver, C Núñez-Otero, W Bahnan, KS Krishnan, O Salin, ... Journal of Medicinal Chemistry 59 (5), 2094-2108, 2016 | 54 | 2016 |
| State of the Art in Respiratory Syncytial Virus Drug Discovery and Development GS Cockerill, JAD Good, N Mathews Journal of Medicinal Chemistry 62 (7), 3206-3227, 2018 | 53 | 2018 |
| Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens CL Shaffer, JAD Good, S Kumar, KS Krishnan, JA Gaddy, JT Loh, ... mBio 7 (2), e00221-16, 2016 | 49 | 2016 |
| Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models JAD Good, F Wang, O Rath, HYK Kaan, SK Talapatra, D Podgórski, ... Journal of Medicinal Chemistry 56 (5), 1878-1893, 2013 | 47 | 2013 |
| Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA JAD Good, C Andersson, S Hansen, J Wall, KS Krishnan, A Begum, ... Cell Chemical Biology 23 (3), 404-14, 2016 | 35 | 2016 |
| Elucidating the functionality of kinesins: An overview of small molecule inhibitors JAD Good, DA Skoufias, F Kozielski Seminars in cell & developmental biology 22 (9), 935-945, 2011 | 34 | 2011 |
| Thiazolino 2-pyridone amide isosteres as inhibitors of Chlamydia trachomatis infectivity JAD Good, M Kulén, J Silver, KS Krishnan, W Bahnan, C Núñez-Otero, ... Journal of Medicinal Chemistry 60 (22), 9393-9399, 2017 | 28 | 2017 |
| Doing the methylene shuffle–Further insights into the inhibition of mitotic kinesin Eg5 with S-trityl l-cysteine MN Abualhasan, JAD Good, K Wittayanarakul, NG Anthony, G Berretta, ... European journal of medicinal chemistry 54, 483-498, 2012 | 27 | 2012 |
| Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion GS Cockerill, RM Angell, A Bedernjak, I Chuckowree, I Fraser, ... Journal of Medicinal Chemistry 64 (7), 3658-3676, 2021 | 24 | 2021 |
| Nitrones for understanding and ameliorating the oxidative stress associated with aging S El Fangour, M Marini, J Good, SJ McQuaker, PG Shiels, RC Hartley Age 31, 269-276, 2009 | 15 | 2009 |
| Synthesis of fluorescent ring-fused 2-pyridone peptidomimetics KS Krishnan, C Bengtsson, JAD Good, S Mirkhanov, E Chorell, ... The Journal of Organic Chemistry 78 (23), 12207-12213, 2013 | 11 | 2013 |
| Synthesis of a solid-phase amino imidazotriazine library via palladium catalyzed direct arylation S Maechling, J Good, SD Lindell Journal of combinatorial chemistry 12 (6), 818-821, 2010 | 8 | 2010 |
| Methyl sulfonamide substituents improve the pharmacokinetic properties of bicyclic 2-pyridone based Chlamydia trachomatis inhibitors M Kulén, C Núñez-Otero, AG Cairns, J Silver, AEG Lindgren, E Wede, ... MedChemComm 10 (11), 1966-1987, 2019 | 6 | 2019 |
| Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant S Sarkar, AE Mayer Bridwell, JAD Good, ER Wang, SR McKee, J Valenta, ... Journal of Medicinal Chemistry 66 (16), 11056-11077, 2023 | 4 | 2023 |
| WO 2016/075296 2,3-Dihydro-thiazolo[3,2-a]pyridin-5-one Derivatives, Intermediates Thereof, And Their Use As Antibacterial Agents JAD Good, AM Kulén, KF Almqvist, AG Cairns, JF Pontén WO Patent WO/2016/075,296, 2016 | 4* | 2016 |
| The Discovery and Development of Eg5 Inhibitors for the Clinic JAD Good, G Berretta, NG Anthony, SP Mackay Kinesins and Cancer, 27-52, 2015 | 4 | 2015 |
Fredrik AlmqvistProfessor in Organic Chemistry, Umeå UniversityVerified email at umu.se
