| FcRn: the neonatal Fc receptor comes of age DC Roopenian, S Akilesh Nature reviews immunology 7 (9), 715-725, 2007 | 2585 | 2007 |
| Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6 K Ozaki, R Spolski, R Ettinger, HP Kim, G Wang, CF Qi, P Hwu, DJ Shaffer, ... The Journal of Immunology 173 (9), 5361-5371, 2004 | 824 | 2004 |
| Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease SB Petkova, S Akilesh, TJ Sproule, GJ Christianson, H Al Khabbaz, ... International immunology 18 (12), 1759-1769, 2006 | 643 | 2006 |
| A catalog of genetic loci associated with kidney function from analyses of a million individuals M Wuttke, Y Li, M Li, KB Sieber, MF Feitosa, M Gorski, A Tin, L Wang, ... Nature genetics 51 (6), 957-972, 2019 | 603 | 2019 |
| The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs DC Roopenian, GJ Christianson, TJ Sproule, AC Brown, S Akilesh, ... The Journal of Immunology 170 (7), 3528-3533, 2003 | 514 | 2003 |
| Podocytes use FcRn to clear IgG from the glomerular basement membrane S Akilesh, TB Huber, H Wu, G Wang, B Hartleben, JB Kopp, JH Miner, ... Proceedings of the National Academy of Sciences 105 (3), 967-972, 2008 | 305 | 2008 |
| Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism S Akilesh, GJ Christianson, DC Roopenian, AS Shaw The Journal of Immunology 179 (7), 4580-4588, 2007 | 298 | 2007 |
| Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis S Akilesh, H Suleiman, H Yu, MC Stander, P Lavin, R Gbadegesin, ... The Journal of clinical investigation 121 (10), 4127-4137, 2011 | 294 | 2011 |
| The MHC class I–like Fc receptor promotes humorally mediated autoimmune disease S Akilesh, S Petkova, TJ Sproule, DJ Shaffer, GJ Christianson, ... The Journal of clinical investigation 113 (9), 1328-1333, 2004 | 232 | 2004 |
| Multicenter clinicopathologic correlation of kidney biopsies performed in COVID-19 patients presenting with acute kidney injury or proteinuria S Akilesh, CC Nast, M Yamashita, K Henriksen, V Charu, ML Troxell, ... American Journal of Kidney Diseases 77 (1), 82-93. e1, 2021 | 201 | 2021 |
| Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria A Teumer, Y Li, S Ghasemi, BP Prins, M Wuttke, T Hermle, A Giri, ... Nature communications 10 (1), 4130, 2019 | 147 | 2019 |
| Rac1 activation in podocytes induces rapid foot process effacement and proteinuria H Yu, H Suleiman, AHJ Kim, JH Miner, A Dani, AS Shaw, S Akilesh Molecular and cellular biology 33 (23), 4755-4764, 2013 | 143 | 2013 |
| The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis J Xie, L Liu, N Mladkova, Y Li, H Ren, W Wang, Z Cui, L Lin, X Hu, X Yu, ... Nature communications 11 (1), 1600, 2020 | 127 | 2020 |
| Customized molecular phenotyping by quantitative gene expression and pattern recognition analysis S Akilesh, DJ Shaffer, D Roopenian Genome research 13 (7), 1719-1727, 2003 | 120 | 2003 |
| COVID-19 vasculopathy: mounting evidence for an indirect mechanism of endothelial injury RF Nicosia, G Ligresti, N Caporarello, S Akilesh, D Ribatti The American Journal of Pathology 191 (8), 1374-1384, 2021 | 90 | 2021 |
| A 3D human renal cell carcinoma-on-a-chip for the study of tumor angiogenesis CP Miller, C Tsuchida, Y Zheng, J Himmelfarb, S Akilesh Neoplasia 20 (6), 610-620, 2018 | 86 | 2018 |
| An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells DB Graham, LM Stephenson, SK Lam, K Brim, HM Lee, J Bautista, ... The Journal of experimental medicine 204 (12), 2889-2897, 2007 | 80 | 2007 |
| B cell–derived IL-4 acts on podocytes to induce proteinuria and foot process effacement AHJ Kim, JJ Chung, S Akilesh, A Koziell, S Jain, JB Hodgin, MJ Miller, ... Jci Insight 2 (21), 2017 | 72 | 2017 |
| Fibrillary glomerulonephritis: clinicopathologic features and atypical cases from a multi-institutional cohort NK Andeen, ML Troxell, M Riazy, RS Avasare, J Lapasia, JA Jefferson, ... Clinical Journal of the American Society of Nephrology 14 (12), 1741-1750, 2019 | 62 | 2019 |
| Monoclonal antibodies directed against human FcRn and their applications GJ Christianson, VZ Sun, S Akilesh, E Pesavento, G Proetzel, ... MAbs 4 (2), 208-216, 2012 | 57 | 2012 |
Andrey ShawSenior Staff Scientist, GenentechVerified email at gene.com
