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Jeff Tan
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Mitochondrial translocation of cofilin is an early step in apoptosis induction
BT Chua, C Volbracht, KO Tan, R Li, VC Yu, P Li
Nature cell biology 5 (12), 1083-1089, 2003
3622003
Identification of chelerythrine as an inhibitor of BclXL function
SL Chan, MC Lee, KO Tan, LK Yang, ASY Lee, H Flotow, NY Fu, ...
Journal of Biological Chemistry 278 (23), 20453-20456, 2003
2292003
MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains
KO Tan, KML Tan, SL Chan, KSY Yee, M Bévort, KC Ang, CY Victor
Journal of Biological Chemistry 276 (4), 2802-2807, 2001
1692001
MAP-1 is a mitochondrial effector of Bax
KO Tan, NY Fu, SK Sukumaran, SL Chan, JH Kang, KL Poon, BS Chen, ...
Proceedings of the National Academy of Sciences 102 (41), 14623-14628, 2005
1462005
A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity
KO Tan, KML Tan, CY Victor
Journal of Biological Chemistry 274 (34), 23687-23690, 1999
741999
The Caenorhabditis elegansSex-determining Protein FEM-2 and Its Human Homologue, hFEM-2, Are Ca2+/Calmodulin-dependent Protein Kinase Phosphatases That Promote Apoptosis
KML Tan, SL Chan, KO Tan, CY Victor
Journal of Biological Chemistry 276 (47), 44193-44202, 2001
662001
F1Aα, a Death Receptor-binding Protein Homologous to theCaenorhabditis elegans Sex-determining Protein, FEM-1, Is a Caspase Substrate That Mediates Apoptosis
SL Chan, KO Tan, L Zhang, KSY Yee, F Ronca, MY Chan, CY Victor
Journal of Biological Chemistry 274 (45), 32461-32468, 1999
431999
Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice.
PCL Yee PTI, Tan SH, Ong KC, Tan KO, Wong KT, Hassan SS
Scientific Report, 4805, 2019
312019
PNMA family: Protein interaction network and cell signalling pathways implicated in cancer and apoptosis
SW Pang, C Lahiri, CL Poh, KO Tan
Cellular signalling 45, 54-62, 2018
292018
Distinct functional domains of PNMA5 mediate protein–protein interaction, nuclear localization, and apoptosis signaling in human cancer cells
YH Lee, SW Pang, CL Poh, KO Tan
Journal of cancer research and clinical oncology 142, 1967-1977, 2016
222016
Molecular characterization of avian muscle titin.
KO Tan, GR Sater, AM Myers, RM Robson, TW Huiatt
Journal of Biological Chemistry 268 (30), 22900-22907, 1993
211993
Emerging strategies for sensitization of therapy resistant tumors toward cancer therapeutics by targeting the Bcl-2 family, TGF-β, Wnt/β-Catenin, RASSF and miRNA regulated …
T Veerasamy, SE Simon, KO Tan
The international journal of biochemistry & cell biology 137, 106016, 2021
152021
PNMA2 mediates heterodimeric interactions and antagonizes chemo-sensitizing activities mediated by members of PNMA family
YH Lee, SW Pang, KO Tan
Biochemical and biophysical research communications 473 (1), 224-229, 2016
152016
Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1
YH Lee, SW Pang, E Revai Lechtich, K Shah, SE Simon, S Ponnusamy, ...
Journal of cancer research and clinical oncology 146, 1751-1764, 2020
142020
Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71
PTI Yee, KO Tan, I Othman, CL Poh
Virology journal 13, 1-12, 2016
142016
Human embryonic stem cell-derived neural lineages as in vitro models for screening the neuroprotective properties of Lignosus rhinocerus (Cooke) Ryvarden
Y Yeo, JBL Tan, LW Lim, KO Tan, BC Heng, WL Lim
BioMed research international 2019, 2019
122019
Pluripotent human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy
MS Yap, YQ Tang, Y Yeo, WL Lim, LW Lim, KO Tan, M Richards, I Othman, ...
Virology journal 13, 1-10, 2016
112016
Alpha-Mangostin activates MOAP-1 tumor suppressor and mitochondrial signaling in MCF-7 human breast cancer cells
SE Simon, HS Lim, FA Jayakumar, EW Tan, KO Tan
Evidence-Based Complementary and Alternative Medicine 2022, 1-12, 2022
102022
Engineered Oncolytic Adenoviruses: An Emerging Approach for Cancer Therapy
CLPKOT Ee Wern Tan, Noraini Abd-Aziz
Pathogens 11 (10), 24, 2022
9*2022
New synthetic phenylquinazoline derivatives induce apoptosis by targeting the pro-survival members of the BCL-2 family
SE Simon, U Ahmed, SM Saad, A Anwar, KM Khan, EW Tan, KO Tan
Bioorganic & Medicinal Chemistry Letters 67, 128731, 2022
82022
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