SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression MJ Vazquez, CA Toro, JM Castellano, F Ruiz-Pino, J Roa, D Beiroa, ... Nature communications 9 (1), 4194, 2018 | 102 | 2018 |
Direct actions of kisspeptins on GnRH neurons permit attainment of fertility but are insufficient to fully preserve gonadotropic axis activity S León, A Barroso, MJ Vázquez, D García-Galiano, M Manfredi-Lozano, ... Scientific reports 6 (1), 19206, 2016 | 85 | 2016 |
Central ceramide signaling mediates obesity-induced precocious puberty V Heras, JM Castellano, D Fernandois, I Velasco, E Rodríguez-Vazquez, ... Cell Metabolism 32 (6), 951-966. e8, 2020 | 69 | 2020 |
Metabolic regulation of female puberty via hypothalamic AMPK–kisspeptin signaling J Roa, A Barroso, F Ruiz-Pino, MJ Vázquez, P Seoane-Collazo, ... Proceedings of the National Academy of Sciences 115 (45), E10758-E10767, 2018 | 69 | 2018 |
Development and validation of a method for precise dating of female puberty in laboratory rodents: the puberty ovarian maturation score (Pub-Score) F Gaytan, C Morales, S Leon, V Heras, A Barroso, MS Avendaño, ... Scientific reports 7 (1), 46381, 2017 | 62 | 2017 |
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3 V Heras, S Sangiao-Alvarellos, M Manfredi-Lozano, MJ Sanchez-Tapia, ... PLoS biology 17 (11), e3000532, 2019 | 57 | 2019 |
Gonadal hormone-dependent vs.-independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis I Velasco, S León, A Barroso, F Ruiz-Pino, V Heras, E Torres, M León, ... Metabolism 98, 84-94, 2019 | 45 | 2019 |
Intergenerational influence of paternal obesity on metabolic and reproductive health parameters of the offspring: male-preferential impact and involvement of Kiss1-mediated … MA Sanchez-Garrido, F Ruiz-Pino, I Velasco, A Barroso, D Fernandois, ... Endocrinology 159 (2), 1005-1018, 2018 | 45 | 2018 |
Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis MF Fondevila, U Fernandez, V Heras, T Parracho, MJ Gonzalez-Rellan, ... Journal of hepatology 77 (1), 15-28, 2022 | 39 | 2022 |
Metabolic and gonadotropic impact of sequential obesogenic insults in the female: influence of the loss of ovarian secretion MA Sanchez-Garrido, F Ruiz-Pino, M Manfredi-Lozano, S Leon, V Heras, ... Endocrinology 156 (8), 2984-2998, 2015 | 39 | 2015 |
Tanycytic networks mediate energy balance by feeding lactate to glucose-insensitive POMC neurons T Lhomme, J Clasadonte, M Imbernon, D Fernandois, F Sauve, E Caron, ... The Journal of Clinical Investigation 131 (18), 2021 | 38 | 2021 |
MCH regulates SIRT1/FoxO1 and reduces POMC neuronal activity to induce hyperphagia, adiposity, and glucose intolerance O Al-Massadi, M Quiñones, J Clasadonte, R Hernandez-Bautista, ... Diabetes 68 (12), 2210-2222, 2019 | 38 | 2019 |
Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21 V Pena-Leon, C Folgueira, S Barja-Fernández, R Pérez-Lois, ... Nature Metabolism 4 (7), 901-917, 2022 | 30 | 2022 |
Sex-biased physiological roles of NPFF1R, the canonical receptor of RFRP-3, in food intake and metabolic homeostasis revealed by its congenital ablation in mice S Leon, I Velasco, MJ Vázquez, A Barroso, D Beiroa, V Heras, ... Metabolism 87, 87-97, 2018 | 18 | 2018 |
Sirt3 in POMC neurons controls energy balance in a sex-and diet-dependent manner M Quiñones, R Hernández-Bautista, D Beiroa, V Heras, FL Torres-Leal, ... Redox Biology 41, 101945, 2021 | 9 | 2021 |
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice J Roa, M Ruiz-Cruz, F Ruiz-Pino, R Onieva, MJ Vazquez, ... Nature Communications 13 (1), 4663, 2022 | 8 | 2022 |
Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons C Perdices-Lopez, MS Avendaño, A Barroso, F Gaytán, F Ruiz-Pino, ... Metabolism 129, 155141, 2022 | 7 | 2022 |
Kappa-opioid receptor blockade ameliorates obesity caused by estrogen withdrawal via promotion of energy expenditure through mTOR pathway A Romero-Picó, MG Novelle, O Al-Massadi, D Beiroa, M Tojo, V Heras, ... International Journal of Molecular Sciences 23 (6), 3118, 2022 | 7 | 2022 |
Congenital ablation of Tacr2 reveals overlapping and redundant roles of NK2R signaling in the control of reproductive axis E Torres, I Velasco, D Franssen, V Heras, F Gaytan, S Leon, VM Navarro, ... American Journal of Physiology-Endocrinology and Metabolism 320 (3), E496-E511, 2021 | 6 | 2021 |
Female puberty overview JM Castellano, V Heras, F Ruiz-Pino, M Tena-Sempere Academic Press, 2018 | 4 | 2018 |