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Olivier Saulnier
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Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes
M Labussière, B Boisselier, K Mokhtari, AL Di Stefano, A Rahimian, ...
Neurology 83 (13), 1200-1206, 2014
2252014
Transcriptional programs define intratumoral heterogeneity of Ewing sarcoma at single-cell resolution
MM Aynaud, O Mirabeau, N Gruel, S Grossetête, V Boeva, S Durand, ...
Cell reports 30 (6), 1767-1779. e6, 2020
1192020
Metabolic regulation of the epigenome drives lethal infantile ependymoma
KA Michealraj, SA Kumar, LJY Kim, FMG Cavalli, D Przelicki, JB Wojcik, ...
Cell 181 (6), 1329-1345. e24, 2020
902020
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy
JK Ocasio, B Babcock, D Malawsky, SJ Weir, L Loo, JM Simon, MJ Zylka, ...
Nature communications 10 (1), 5829, 2019
862019
Failure of human rhombic lip differentiation underlies medulloblastoma formation
LD Hendrikse, P Haldipur, O Saulnier, J Millman, AH Sjoboen, ...
Nature 609 (7929), 1021-1028, 2022
692022
TCF12 is mutated in anaplastic oligodendroglioma
K Labreche, I Simeonova, A Kamoun, V Gleize, D Chubb, E Letouzé, ...
Nature communications 6, 2015
502015
ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin
I Tanaka, A Chakraborty, O Saulnier, C Benoit-Pilven, S Vacher, D Labiod, ...
Nucleic acids research 48 (5), 2676-2693, 2020
342020
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate
J Zagozewski, GM Shahriary, LC Morrison, O Saulnier, M Stromecki, ...
Nature Communications 11 (1), 3627, 2020
252020
Targeting microglial metabolic rewiring synergizes with immune-checkpoint blockade therapy for glioblastoma
Z Ye, X Ai, K Yang, Z Yang, F Fei, X Liao, Z Qiu, RC Gimple, H Yuan, ...
Cancer discovery 13 (4), 974-1001, 2023
162023
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions
J Vibert, O Saulnier, C Collin, F Petit, KJE Borgman, J Vigneau, M Gautier, ...
Molecular Cell 82 (13), 2458-2471. e9, 2022
162022
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion
O Saulnier, K Guedri-Idjouadiene, MM Aynaud, A Chakraborty, J Bruyr, ...
Nucleic Acids Research 49 (9), 5038-5056, 2021
132021
A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis
H Zou, B Poore, EE Brown, J Qian, B Xie, E Asimakidou, V Razskazovskiy, ...
Nature cell biology 25 (3), 493-507, 2023
92023
Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression
J Zagozewski, S Borlase, BJ Guppy, L Coudière-Morrison, GM Shahriary, ...
Communications Biology 5 (1), 697, 2022
92022
The LIN28B–let‐7–PBK pathway is essential for group 3 medulloblastoma tumor growth and survival
SW Shahab, CM Roggeveen, J Sun, H Kunhiraman, LF McSwain, ...
Molecular Oncology 17 (9), 1784-1802, 2023
52023
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism
L Zhao, Z Qiu, Z Yang, L Xu, TM Pearce, Q Wu, K Yang, FL Li, O Saulnier, ...
Nature Cancer, 1-20, 2024
32024
Abstract NG06: Tracing the developmental origins of group 3 medulloblastoma
O Saulnier
Cancer Research 84 (7_Supplement), NG06-NG06, 2024
2024
A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and MYC that promotes group 3 medulloblastoma
K Katsushima, K Joshi, M Yuan, B Romero, M Batish, S Stapleton, G Jallo, ...
Cell Reports 43 (3), 2024
2024
miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4
M Yuan, I Mahmud, K Katsushima, K Joshi, O Saulnier, R Pokhrel, B Lee, ...
Acta Neuropathologica Communications 11 (1), 203, 2023
2023
Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma
V Daggubati, A Vykunta, A Choudhury, Z Qadeer, K Mirchia, O Saulnier, ...
Research Square, 2023
2023
MDB-21. THE OTX2-REGULATED ALTERNATIVE SPLICING LANDSCAPE CONTROLS DIFFERENTIATION AND RECONSTITUTES THE DEVELOPMENTAL ORIGINS OF GROUP 3 MEDULLOBLASTOMA
O Saulnier, J Zagozewski, L Liang, LD Hendrikse, V Gordon, KA Aldinger, ...
Neuro-Oncology 25 (Suppl 1), i66, 2023
2023
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