An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia A Sehgal, S Barros, L Ivanciu, B Cooley, J Qin, T Racie, J Hettinger, ... Nature medicine 21 (5), 492-497, 2015 | 291 | 2015 |
TGN1412: from discovery to disaster H Attarwala Journal of Young Pharmacists 2 (3), 332-336, 2010 | 289 | 2010 |
Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates JK Nair, H Attarwala, A Sehgal, Q Wang, K Aluri, X Zhang, M Gao, J Liu, ... Nucleic acids research 45 (19), 10969-10977, 2017 | 214 | 2017 |
Single‐dose pharmacokinetics and pharmacodynamics of transthyretin targeting N‐acetylgalactosamine–small interfering ribonucleic acid conjugate, vutrisiran, in healthy subjects BA Habtemariam, V Karsten, H Attarwala, V Goel, M Melch, VA Clausen, ... Clinical Pharmacology & Therapeutics 109 (2), 372-382, 2021 | 97 | 2021 |
Multi-compartmental oral delivery systems for nucleic acid therapy in the gastrointestinal tract C Kriegel, H Attarwala, M Amiji Advanced drug delivery reviews 65 (6), 891-901, 2013 | 96 | 2013 |
Patisiran pharmacokinetics, pharmacodynamics, and exposure‐response analyses in the phase 3 APOLLO trial in patients with hereditary transthyretin‐mediated (hATTR) amyloidosis X Zhang, V Goel, H Attarwala, MT Sweetser, VA Clausen, GJ Robbie The Journal of Clinical Pharmacology 60 (1), 37-49, 2020 | 90 | 2020 |
A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus A August, HZ Attarwala, S Himansu, S Kalidindi, S Lu, R Pajon, S Han, ... Nature medicine 27 (12), 2224-2233, 2021 | 75 | 2021 |
Role of antibodies in cancer targeting H Attarwala Journal of natural science, biology, and medicine 1 (1), 53, 2010 | 70 | 2010 |
Multi-compartmental macrophage delivery MM Amiji, M Kalariya, S Jain, H Attarwala US Patent 10,500,156, 2019 | 34 | 2019 |
Cosilencing Intestinal Transglutaminase-2 and Interleukin-15 Using Gelatin-Based Nanoparticles in an in Vitro Model of Celiac Disease H Attarwala, V Clausen, P Chaturvedi, MM Amiji Molecular Pharmaceutics 14 (9), 3036-3044, 2017 | 33 | 2017 |
Multi-compartmental nanoparticles-in-emulsion formulation for macrophage-specific anti-inflammatory gene delivery H Attarwala, M Amiji Pharmaceutical research 29, 1637-1649, 2012 | 22 | 2012 |
Oral nucleic acid therapy using multicompartmental delivery systems H Attarwala, M Han, J Kim, M Amiji Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 10 (2 …, 2018 | 20 | 2018 |
Handbook of polyester drug delivery systems MNVR Kumar CRC Press, 2017 | 12 | 2017 |
Translational pharmacokinetic/pharmacodynamic model for mRNA-3927, an investigational therapeutic for the treatment of propionic acidemia H Attarwala, M Lumley, M Liang, V Ivaturi, J Senn nucleic acid therapeutics 33 (2), 141-147, 2023 | 11 | 2023 |
Lipid nanocarriers in cancer diagnosis and therapy E Souto Smithers Rapra, 2011 | 10 | 2011 |
Homeopathy-the science of holistic healing: An overview H Attarwala, D Bathija, A Akhil, B Philip, A Mathew, KKM Ahmed Pharmacognosy Magazine 2 (5), 7, 2006 | 10 | 2006 |
Phase 1 Study of ALN-TTRsc02, a Subcutaneously Administered Investigational RNAi Therapeutic for the Treatment of Transthyretin-Mediated Amyloidosis JV Jorg Taubel , Tracy Zimmermann , Verena Karsten , Clarida Martinez , Amy ... 16th International Symposium on Amyloidosis (ISA), 2018 | 9* | 2018 |
GalNAc-siRNA conjugate ALN-HBV targets a highly conserved, pan-genotypic X-orf viral site and mediates profound and durable HBsAg silencing in vitro and in vivo L Sepp-Lorenzino, AG Sprague, T Mayo, TM Nguyen, SS Morskaya, H Xu, ... Hepatology 62, 224A-225A, 2015 | 9 | 2015 |
Co-silencing of tissue transglutaminase-2 and interleukin-15 genes in a celiac disease mimetic mouse model using a nanoparticle-in-microsphere oral system HZ Attarwala, K Suri, MM Amiji Molecular Pharmaceutics 18 (8), 3099-3107, 2021 | 8 | 2021 |
Rational design and in vivo characterization of mRNA-encoded broadly neutralizing antibody combinations against HIV-1 E Narayanan, S Falcone, SM Elbashir, H Attarwala, K Hassett, ... Antibodies 11 (4), 67, 2022 | 7 | 2022 |