Control of PD-L1 expression by oncogenic activation of the AKT–mTOR pathway in non–small cell lung cancer KJ Lastwika, W Wilson III, QK Li, J Norris, H Xu, SR Ghazarian, ... Cancer research 76 (2), 227-238, 2016 | 717 | 2016 |
Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study W Wu, LA Pierce, Y Zhang, SNJ Pipavath, TW Randolph, KJ Lastwika, ... European radiology 29, 6100-6108, 2019 | 45 | 2019 |
Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo JP Robinson, MW VanBrocklin, KJ Lastwika, AJ McKinney, S Brandner, ... Oncogene 30 (11), 1341-1350, 2011 | 41 | 2011 |
Targeted delivery of NRASQ61R and Cre‐recombinase to post‐natal melanocytes induces melanoma in Ink4a/Arflox/lox mice MW VanBrocklin, JP Robinson, KJ Lastwika, JD Khoury, SL Holmen Pigment cell & melanoma research 23 (4), 531-541, 2010 | 36 | 2010 |
Tumor-derived autoantibodies identify malignant pulmonary nodules KJ Lastwika, J Kargl, Y Zhang, X Zhu, E Lo, D Shelley, JJ Ladd, W Wu, ... American journal of respiratory and critical care medicine 199 (10), 1257-1266, 2019 | 29 | 2019 |
Phosphorylation of connexin 43 at MAPK, PKC or CK1 sites each distinctly alter the kinetics of epidermal wound repair KJ Lastwika, CA Dunn, JL Solan, PD Lampe Journal of cell science 132 (18), jcs234633, 2019 | 16 | 2019 |
Proteomic analysis, immune dysregulation, and pathway interconnections with obesity CB Garrison, KJ Lastwika, Y Zhang, CI Li, PD Lampe Journal of proteome research 16 (1), 274-287, 2017 | 13 | 2017 |
CD133 as a biomarker for an autoantibody-to-immunoPET paradigm for the early detection of small cell lung cancer AG Kunihiro, SM Sarrett, KJ Lastwika, JL Solan, T Pisarenko, O Keinänen, ... Journal of Nuclear Medicine 63 (11), 1701-1707, 2022 | 9 | 2022 |
Ink4a/Arf loss promotes tumor recurrence following Ras inhibition MW VanBrocklin, JP Robinson, KJ Lastwika, AJ McKinney, HM Gach, ... Neuro-oncology 14 (1), 34-42, 2012 | 9 | 2012 |
Resistance mechanisms to genetic suppression of mutant NRAS in melanoma JP Robinson, VW Rebecca, DA Kircher, MR Silvis, I Smalley, GT Gibney, ... Melanoma research 27 (6), 545-557, 2017 | 7 | 2017 |
PI3K/AKT/mTOR pathway activation drives expression of the immune inhibitory ligand PD-L1 in NSCLC. K Lastwika, W Wilson, PA Dennis Cancer Research 73 (8_Supplement), 4981-4981, 2013 | 7 | 2013 |
Akt signaling accelerates tumor recurrence following ras inhibition in the context of ink4a/arf loss GL Robinson, JP Robinson, KJ Lastwika, SL Holmen, MW VanBrocklin Genes & Cancer 4 (11-12), 476-485, 2013 | 6 | 2013 |
Posttranslational modifications induce autoantibodies with risk prediction capability in patients with small cell lung cancer KJ Lastwika, A Kunihiro, JL Solan, Y Zhang, LR Taverne, D Shelley, ... Science translational medicine 15 (678), eadd8469, 2023 | 4 | 2023 |
Regulation and Consequences of PD-L1 Expression in Non-Small Cell Lung Cancer KJ Lastwika The George Washington University, 2014 | 3 | 2014 |
Abstract A12: Non-small cell lung tumor-derived autoantibodies can distinguish benign from malignant pulmonary nodules KJ Lastwika, J Kargl, Y Zhang, X Zhu, D Shelley, E Lo, W Wu, ... Clinical Cancer Research 24 (17_Supplement), A12-A12, 2018 | 2 | 2018 |
Evaluating CD133 as a Radiotheranostic Target in Small-Cell Lung Cancer SM Sarrett, C Rodriguez, S Delaney, MM Hosny, J Sebastiano, ... Molecular Pharmaceutics, 2024 | 1 | 2024 |
Multi-Omic Biomarkers Improve Indeterminate Pulmonary Nodule Malignancy Risk Assessment KJ Lastwika, W Wu, Y Zhang, N Ma, M Zečević, SNJ Pipavath, ... Cancers 15 (13), 3418, 2023 | 1 | 2023 |
A16 Autoantibody-Antigen Complexes Can Detect Limited-Stage Small-Cell Lung Cancer KJ Lastwika, Y Zhang, JJ Ladd, PP Massion, AM Houghton, PD Lampe Journal of Thoracic Oncology 15 (2), S17, 2020 | 1 | 2020 |
Increased NSCLC tumorigenesis in mice fed a high fat diet is associated with increased plasma IGF-1 levels and PD-1 expression in CD4+ tumor-infiltrating lymphocytes RM Memmott, K Pearman, J Gills, T Tullot, V Wong, B Singer, K Lastwika, ... Cancer Research 77 (13_Supplement), 237-237, 2017 | 1 | 2017 |
A high-fat diet promotes tumorigenesis in two mouse models of K-ras-driven lung cancer J Norris, K Pearman, R Memmott, K Lastwika, J Gills, P Dennis Cancer Research 76 (14_Supplement), 4330-4330, 2016 | 1 | 2016 |