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Kristin J Lastwika
Kristin J Lastwika
Fred Hutchinson Cancer Research Center
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Control of PD-L1 expression by oncogenic activation of the AKT–mTOR pathway in non–small cell lung cancer
KJ Lastwika, W Wilson III, QK Li, J Norris, H Xu, SR Ghazarian, ...
Cancer research 76 (2), 227-238, 2016
7172016
Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study
W Wu, LA Pierce, Y Zhang, SNJ Pipavath, TW Randolph, KJ Lastwika, ...
European radiology 29, 6100-6108, 2019
452019
Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo
JP Robinson, MW VanBrocklin, KJ Lastwika, AJ McKinney, S Brandner, ...
Oncogene 30 (11), 1341-1350, 2011
412011
Targeted delivery of NRASQ61R and Cre‐recombinase to post‐natal melanocytes induces melanoma in Ink4a/Arflox/lox mice
MW VanBrocklin, JP Robinson, KJ Lastwika, JD Khoury, SL Holmen
Pigment cell & melanoma research 23 (4), 531-541, 2010
362010
Tumor-derived autoantibodies identify malignant pulmonary nodules
KJ Lastwika, J Kargl, Y Zhang, X Zhu, E Lo, D Shelley, JJ Ladd, W Wu, ...
American journal of respiratory and critical care medicine 199 (10), 1257-1266, 2019
292019
Phosphorylation of connexin 43 at MAPK, PKC or CK1 sites each distinctly alter the kinetics of epidermal wound repair
KJ Lastwika, CA Dunn, JL Solan, PD Lampe
Journal of cell science 132 (18), jcs234633, 2019
162019
Proteomic analysis, immune dysregulation, and pathway interconnections with obesity
CB Garrison, KJ Lastwika, Y Zhang, CI Li, PD Lampe
Journal of proteome research 16 (1), 274-287, 2017
132017
CD133 as a biomarker for an autoantibody-to-immunoPET paradigm for the early detection of small cell lung cancer
AG Kunihiro, SM Sarrett, KJ Lastwika, JL Solan, T Pisarenko, O Keinänen, ...
Journal of Nuclear Medicine 63 (11), 1701-1707, 2022
92022
Ink4a/Arf loss promotes tumor recurrence following Ras inhibition
MW VanBrocklin, JP Robinson, KJ Lastwika, AJ McKinney, HM Gach, ...
Neuro-oncology 14 (1), 34-42, 2012
92012
Resistance mechanisms to genetic suppression of mutant NRAS in melanoma
JP Robinson, VW Rebecca, DA Kircher, MR Silvis, I Smalley, GT Gibney, ...
Melanoma research 27 (6), 545-557, 2017
72017
PI3K/AKT/mTOR pathway activation drives expression of the immune inhibitory ligand PD-L1 in NSCLC.
K Lastwika, W Wilson, PA Dennis
Cancer Research 73 (8_Supplement), 4981-4981, 2013
72013
Akt signaling accelerates tumor recurrence following ras inhibition in the context of ink4a/arf loss
GL Robinson, JP Robinson, KJ Lastwika, SL Holmen, MW VanBrocklin
Genes & Cancer 4 (11-12), 476-485, 2013
62013
Posttranslational modifications induce autoantibodies with risk prediction capability in patients with small cell lung cancer
KJ Lastwika, A Kunihiro, JL Solan, Y Zhang, LR Taverne, D Shelley, ...
Science translational medicine 15 (678), eadd8469, 2023
42023
Regulation and Consequences of PD-L1 Expression in Non-Small Cell Lung Cancer
KJ Lastwika
The George Washington University, 2014
32014
Abstract A12: Non-small cell lung tumor-derived autoantibodies can distinguish benign from malignant pulmonary nodules
KJ Lastwika, J Kargl, Y Zhang, X Zhu, D Shelley, E Lo, W Wu, ...
Clinical Cancer Research 24 (17_Supplement), A12-A12, 2018
22018
Evaluating CD133 as a Radiotheranostic Target in Small-Cell Lung Cancer
SM Sarrett, C Rodriguez, S Delaney, MM Hosny, J Sebastiano, ...
Molecular Pharmaceutics, 2024
12024
Multi-Omic Biomarkers Improve Indeterminate Pulmonary Nodule Malignancy Risk Assessment
KJ Lastwika, W Wu, Y Zhang, N Ma, M Zečević, SNJ Pipavath, ...
Cancers 15 (13), 3418, 2023
12023
A16 Autoantibody-Antigen Complexes Can Detect Limited-Stage Small-Cell Lung Cancer
KJ Lastwika, Y Zhang, JJ Ladd, PP Massion, AM Houghton, PD Lampe
Journal of Thoracic Oncology 15 (2), S17, 2020
12020
Increased NSCLC tumorigenesis in mice fed a high fat diet is associated with increased plasma IGF-1 levels and PD-1 expression in CD4+ tumor-infiltrating lymphocytes
RM Memmott, K Pearman, J Gills, T Tullot, V Wong, B Singer, K Lastwika, ...
Cancer Research 77 (13_Supplement), 237-237, 2017
12017
A high-fat diet promotes tumorigenesis in two mouse models of K-ras-driven lung cancer
J Norris, K Pearman, R Memmott, K Lastwika, J Gills, P Dennis
Cancer Research 76 (14_Supplement), 4330-4330, 2016
12016
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