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Joan Coines
Joan Coines
IBMB-CSIC
Verified email at ub.edu - Homepage
Title
Cited by
Cited by
Year
O-/N-/S-Specificity in Glycosyltransferase Catalysis: From Mechanistic Understanding to Engineering
D Teze, J Coines, F Fredslund, KD Dubey, GN Bidart, PD Adams, ...
ACS Catalysis 11 (3), 1810-1815, 2021
422021
Modeling catalytic reaction mechanisms in glycoside hydrolases
J Coines, L Raich, C Rovira
Current Opinion in Chemical Biology 53, 183-191, 2019
302019
Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations
MAB Morais, J Coines, MN Domingues, RAS Pirolla, CCC Tonoli, ...
Nature Communications 12 (1), 367, 2021
282021
Oxazoline or oxazolinium ion? the protonation state and conformation of the reaction intermediate of chitinase enzymes revisited
J Coines, M Alfonso-Prieto, X Biarnés, A Planas, C Rovira
Chemistry–A European Journal, 2018
282018
A Single Point Mutation Converts GH84 O-GlcNAc Hydrolases into Phosphorylases: Experimental and Theoretical Evidence
D Teze, J Coines, L Raich, V Kalichuk, C Solleux, C Tellier, C André-Miral, ...
Journal of the American Chemical Society 142 (5), 2120-2124, 2020
272020
Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐l‐Arabinofuranosidase Inhibitor
NGS McGregor, J Coines, V Borlandelli, S Amaki, M Artola, A Nin‐Hill, ...
Angewandte Chemie 133 (11), 5818-5822, 2021
262021
Structural and kinetic features of aldehyde dehydrogenase 1A (ALDH1A) subfamily members, cancer stem cell markers active in retinoic acid biosynthesis
R Pequerul, J Vera, J Giménez-Dejoz, I Crespo, J Coines, S Porté, ...
Archives of biochemistry and biophysics 681, 108256, 2020
242020
Computer simulation to rationalize “rational” engineering of glycoside hydrolases and glycosyltransferases
J Coines, I Cuxart, D Teze, C Rovira
The Journal of Physical Chemistry B 126 (4), 802-812, 2022
152022
Conformational itinerary of sucrose during hydrolysis by retaining amylosucrase
S Alonso-Gil, J Coines, I André, C Rovira
Frontiers in chemistry 7, 269, 2019
142019
An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1, 6-α-mannanase inhibitor
T Belz, Y Jin, J Coines, C Rovira, GJ Davies, SJ Williams
Chemical Communications 53 (66), 9238-9241, 2017
102017
Enzymatic Hydrolysis of Human Milk Oligosaccharides. The Molecular Mechanism of Bifidobacterium Bifidum Lacto-N-biosidase
I Cuxart, J Coines, O Esquivias, M Faijes, A Planas, X Biarnés, C Rovira
ACS catalysis 12 (8), 4737-4743, 2022
92022
Glucose transport via the pseudomonad porin OprB: implications for the design of Trojan Horse anti-infectives.
J Coines, S Acosta-Gutierrez, I Bodrenko, C Rovira, M Ceccarelli
Physical Chemistry Chemical Physics, 2019
92019
Enzymatic C4‐Epimerization of UDP‐Glucuronic Acid: Precisely Steered Rotation of a Transient 4‐Keto Intermediate for an Inverted Reaction without Decarboxylation
AJE Borg, O Esquivias, J Coines, C Rovira, B Nidetzky
Angewandte Chemie International Edition 62 (4), e202211937, 2023
2023
Mechanistic insights into substrate-assisted catalysis in glycosidases by means of QM/MM molecular dynamics
J Coines Lopez-Nieto
Universitat de Barcelona, 2021
2021
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