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Kevin M. Wernke
Kevin M. Wernke
Assistant Professor of Chemistry, Colorado Mesa University
Verified email at coloradomesa.edu - Homepage
Title
Cited by
Cited by
Year
Structure elucidation of colibactin and its DNA cross-links
M Xue, CS Kim, AR Healy, KM Wernke, Z Wang, MC Frischling, EE Shine, ...
Science 365 (6457), eaax2685, 2019
1832019
Structure and bioactivity of colibactin
KM Wernke, M Xue, A Tirla, CS Kim, JM Crawford, SB Herzon
Bioorganic & medicinal chemistry letters 30 (15), 127280, 2020
532020
Synthesis and reactivity of precolibactin 886
AR Healy, KM Wernke, CS Kim, NR Lees, JM Crawford, SB Herzon
Nature chemistry 11 (10), 890-898, 2019
342019
Depurination of colibactin-derived interstrand cross-links
M Xue, KM Wernke, SB Herzon
Biochemistry 59 (7), 892-900, 2020
282020
Employing chemical synthesis to study the structure and function of colibactin, a “dark matter” metabolite
PC Williams, KM Wernke, A Tirla, SB Herzon
Natural product reports 37 (11), 1532-1548, 2020
122020
Theaflavins from black tea affect growth, development, and motility in Dictyostelium discoideum
AN Ilacqua, JA Shettler, KM Wernke, JK Skalla, KJ McQuade
Biochemical and biophysical research communications 491 (2), 449-454, 2017
92017
Probing microbiome genotoxicity: a stable colibactin provides insight into structure–activity relationships and facilitates mechanism of action studies
KM Wernke, A Tirla, M Xue, YV Surovtseva, FS Menges, SB Herzon
Journal of the American Chemical Society 143 (38), 15824-15833, 2021
82021
Structure elucidation of colibactin and its DNA cross-links. Science 365: eaax2685
M Xue, CS Kim, AR Healy, KM Wernke, Z Wang, MC Frischling, EE Shine, ...
82019
Structure elucidation of colibactin
M Xue, CS Kim, AR Healy, KM Wernke, Z Wang, MC Frischling, EE Shine, ...
bioRxiv, 574053, 2019
62019
The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors
MW Dougherty, R Valdés-Mas, KM Wernke, RZ Gharaibeh, Y Yang, ...
Neoplasia 43, 100918, 2023
42023
On the stability and spectroscopic properties of 5-hydroxyoxazole-4-carboxylic acid derivatives
A Tirla, KM Wernke, SB Herzon
Organic letters 23 (14), 5457-5460, 2021
32021
The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links
M Altshuller, X He, EJ MacKrell, KM Wernke, JWH Wang, S Sellés-Baiget, ...
bioRxiv, 2024.01. 30.576698, 2024
2024
Synthetic colibactins reveal the structural and biological mode-of-action of a microbial carcinogen
MW Dougherty, R Valdés-Mas, KM Wernke, RZ Gharaibeh, A Riva, ...
Cancer Research 83 (7_Supplement), 1215-1215, 2023
2023
Chemoproteomic identification and functional characterization of colibactin-modified proteins that drive colorectal cancer progression
N Qiu, D Abegg, D Pechalrieu, KM Wernke, SB Herzon, A Adibekian
MOLECULAR & CELLULAR PROTEOMICS 21 (8), S52-S52, 2022
2022
Synthetic Studies of Colibactin, a Carcinogenic Gut Microbiome Metabolite
KM Wernke
Yale University, 2022
2022
Chemical Microbiology and Synthesis Reveals the Structure of Colibactin and its Mode of Genotoxicity
D Trauner, BS Matsuura
Synfacts 15 (12), 1439, 2019
2019
Addendum: Synthesis and reactivity of precolibactin 886
AR Healy, KM Wernke, CS Kim, NR Lees, JM Crawford, SB Herzon
Nature chemistry 11 (12), 1167-1167, 2019
2019
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