| Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy SJ Im, M Hashimoto, MY Gerner, J Lee, HT Kissick, MC Burger, Q Shan, ... Nature 537 (7620), 417-421, 2016 | 1644 | 2016 |
| Differentiation and persistence of memory CD8+ T cells depend on T cell factor 1 X Zhou, S Yu, DM Zhao, JT Harty, VP Badovinac, HH Xue Immunity 33 (2), 229-240, 2010 | 704 | 2010 |
| LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6 YS Choi, JA Gullicksrud, S Xing, Z Zeng, Q Shan, F Li, PE Love, W Peng, ... Nature immunology 16 (9), 980-990, 2015 | 323 | 2015 |
| Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8+ T cell differentiation TC Wirth, HH Xue, D Rai, JT Sabel, T Bair, JT Harty, VP Badovinac Immunity 33 (1), 128-140, 2010 | 298 | 2010 |
| TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow Q Yang, F Li, C Harly, S Xing, L Ye, X Xia, H Wang, X Wang, S Yu, X Zhou, ... Nature immunology 16 (10), 1044-1050, 2015 | 272 | 2015 |
| IL-2 negatively regulates IL-7 receptor α chain expression in activated T lymphocytes HH Xue, PE Kovanen, CA Pise-Masison, M Berg, MF Radovich, JN Brady, ... Proceedings of the National Academy of Sciences 99 (21), 13759-13764, 2002 | 234 | 2002 |
| Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity S Xing, F Li, Z Zeng, Y Zhao, S Yu, Q Shan, Y Li, FC Phillips, PK Maina, ... Nature immunology 17 (6), 695-703, 2016 | 210 | 2016 |
| The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy S Yu, X Zhou, FC Steinke, C Liu, SC Chen, O Zagorodna, X Jing, ... Immunity 37 (5), 813-826, 2012 | 210 | 2012 |
| Constitutive activation of Wnt signaling favors generation of memory CD8 T cells DM Zhao, S Yu, X Zhou, JS Haring, W Held, VP Badovinac, JT Harty, ... The Journal of Immunology 184 (3), 1191-1199, 2010 | 187 | 2010 |
| IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo GR Starbeck-Miller, HH Xue, JT Harty Journal of Experimental Medicine 211 (1), 105-120, 2014 | 186 | 2014 |
| TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells FC Steinke, S Yu, X Zhou, B He, W Yang, B Zhou, H Kawamoto, J Zhu, ... Nature immunology 15 (7), 646-656, 2014 | 173 | 2014 |
| GA binding protein regulates interleukin 7 receptor α-chain gene expression in T cells HH Xue, J Bollenbacher, V Rovella, R Tripuraneni, YB Du, CY Liu, ... Nature immunology 5 (10), 1036-1044, 2004 | 162 | 2004 |
| CD8+ T lymphocyte self-renewal during effector cell determination WHW Lin, SA Nish, B Yen, YH Chen, WC Adams, R Kratchmarov, ... Cell reports 17 (7), 1773-1782, 2016 | 150 | 2016 |
| The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage Q Shan, Z Zeng, S Xing, F Li, SM Hartwig, JA Gullicksrud, SP Kurup, ... Nature immunology 18 (8), 931-939, 2017 | 144 | 2017 |
| The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity S Gautam, J Fioravanti, W Zhu, JB Le Gall, P Brohawn, NE Lacey, J Hu, ... Nature immunology 20 (3), 337-349, 2019 | 134 | 2019 |
| Cutting edge: generation of memory precursors and functional memory CD8+ T cells depends on T cell factor-1 and lymphoid enhancer-binding factor-1 X Zhou, HH Xue The Journal of Immunology 189 (6), 2722-2726, 2012 | 122 | 2012 |
| TCF1 in T cell immunity: a broadened frontier X Zhao, Q Shan, HH Xue Nature Reviews Immunology 22 (3), 147-157, 2022 | 119 | 2022 |
| CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions SA Nish, KD Zens, R Kratchmarov, WHW Lin, WC Adams, YH Chen, ... Journal of Experimental Medicine 214 (1), 39-47, 2017 | 111 | 2017 |
| Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages X Song, W Hu, H Yu, L Zhao, Y Zhao, X Zhao, HH Xue, Y Zhao Cytometry Part A 103 (2), 136-145, 2023 | 107 | 2023 |
| Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses J Yang, X Lin, Y Pan, J Wang, P Chen, H Huang, HH Xue, J Gao, ... Elife 5, e17936, 2016 | 105 | 2016 |
Vladimir BadovinacDepartment of PathologyVerified email at uiowa.edu
