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Lionel Sanz
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The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin
T Nagano, JA Mitchell, LA Sanz, FM Pauler, AC Ferguson-Smith, R Feil, ...
Science 322 (5908), 1717-1720, 2008
11172008
Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals
LA Sanz, SR Hartono, YW Lim, S Steyaert, A Rajpurkar, PA Ginno, X Xu, ...
Molecular cell 63 (1), 167-178, 2016
4972016
Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
CT Stork, M Bocek, MP Crossley, J Sollier, LA Sanz, F Chédin, T Swigut, ...
Elife 5, e17548, 2016
2782016
Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region
EW Loomis, LA Sanz, F Chédin, PJ Hagerman
PLoS genetics 10 (4), e1004294, 2014
2152014
High-resolution, strand-specific R-loop mapping via S9. 6-based DNA–RNA immunoprecipitation and high-throughput sequencing
LA Sanz, F Chédin
Nature protocols 14 (6), 1734-1755, 2019
1882019
Genome-wide DNA hypomethylation and RNA: DNA hybrid accumulation in Aicardi–Goutières syndrome
YW Lim, LA Sanz, X Xu, SR Hartono, F Chedin
Elife 4, e08007, 2015
1802015
Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals
A Henckel, K Nakabayashi, LA Sanz, R Feil, K Hata, P Arnaud
Human molecular genetics 18 (18), 3375-3383, 2009
1572009
DNA Topoisomerase I differentially modulates R-loops across the human genome
SG Manzo, SR Hartono, LA Sanz, J Marinello, S De Biasi, A Cossarizza, ...
Genome biology 19, 1-18, 2018
1492018
Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites
A Promonet, I Padioleau, Y Liu, L Sanz, A Biernacka, AL Schmitz, ...
Nature communications 11 (1), 3940, 2020
1312020
A mono‐allelic bivalent chromatin domain controls tissue‐specific imprinting at Grb10
LA Sanz, S Chamberlain, JC Sabourin, A Henckel, T Magnuson, ...
The EMBO journal 27 (19), 2523-2532, 2008
912008
Recognition of RNA by the S9. 6 antibody creates pervasive artifacts when imaging RNA: DNA hybrids
JA Smolka, LA Sanz, SR Hartono, F Chédin
Journal of Cell Biology 220 (6), e202004079, 2021
892021
Best practices for the visualization, mapping, and manipulation of R‐loops
F Chédin, SR Hartono, LA Sanz, V Vanoosthuyse
The EMBO Journal 40 (4), e106394, 2021
672021
EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos
G Auclair, J Borgel, LA Sanz, J Vallet, S Guibert, M Dumas, P Cavelier, ...
Genome research 26 (2), 192-202, 2016
672016
Ultra-deep coverage single-molecule R-loop footprinting reveals principles of R-loop formation
M Malig, SR Hartono, JM Giafaglione, LA Sanz, F Chedin
Journal of molecular biology 432 (7), 2271-2288, 2020
602020
CARM1 inhibition enables immunotherapy of resistant tumors by dual action on tumor cells and T cells
S Kumar, Z Zeng, A Bagati, RE Tay, LA Sanz, SR Hartono, Y Ito, ...
Cancer discovery 11 (8), 2050-2071, 2021
532021
RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2
C Alecki, V Chiwara, LA Sanz, D Grau, O Arias Pérez, EL Boulier, ...
Nature communications 11 (1), 1781, 2020
532020
Genome-wide DNA demethylation in mammals
LA Sanz, SK Kota, R Feil
Genome biology 11 (3), 1-4, 2010
502010
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation
P Richard, S Feng, YL Tsai, W Li, P Rinchetti, U Muhith, J Irizarry-Cole, ...
Autophagy 17 (8), 1889-1906, 2021
372021
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma
V Giuliani, MA Miller, CY Liu, SR Hartono, CA Class, CA Bristow, E Suzuki, ...
Nature communications 12 (1), 4626, 2021
352021
Genomic patterns of transcription–replication interactions in mouse primary B cells
CP St Germain, H Zhao, V Sinha, LA Sanz, F Chédin, JH Barlow
Nucleic Acids Research 50 (4), 2051-2073, 2022
142022
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Articles 1–20