The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin T Nagano, JA Mitchell, LA Sanz, FM Pauler, AC Ferguson-Smith, R Feil, ... Science 322 (5908), 1717-1720, 2008 | 1117 | 2008 |
Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals LA Sanz, SR Hartono, YW Lim, S Steyaert, A Rajpurkar, PA Ginno, X Xu, ... Molecular cell 63 (1), 167-178, 2016 | 497 | 2016 |
Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage CT Stork, M Bocek, MP Crossley, J Sollier, LA Sanz, F Chédin, T Swigut, ... Elife 5, e17548, 2016 | 278 | 2016 |
Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region EW Loomis, LA Sanz, F Chédin, PJ Hagerman PLoS genetics 10 (4), e1004294, 2014 | 215 | 2014 |
High-resolution, strand-specific R-loop mapping via S9. 6-based DNA–RNA immunoprecipitation and high-throughput sequencing LA Sanz, F Chédin Nature protocols 14 (6), 1734-1755, 2019 | 188 | 2019 |
Genome-wide DNA hypomethylation and RNA: DNA hybrid accumulation in Aicardi–Goutières syndrome YW Lim, LA Sanz, X Xu, SR Hartono, F Chedin Elife 4, e08007, 2015 | 180 | 2015 |
Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals A Henckel, K Nakabayashi, LA Sanz, R Feil, K Hata, P Arnaud Human molecular genetics 18 (18), 3375-3383, 2009 | 157 | 2009 |
DNA Topoisomerase I differentially modulates R-loops across the human genome SG Manzo, SR Hartono, LA Sanz, J Marinello, S De Biasi, A Cossarizza, ... Genome biology 19, 1-18, 2018 | 149 | 2018 |
Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites A Promonet, I Padioleau, Y Liu, L Sanz, A Biernacka, AL Schmitz, ... Nature communications 11 (1), 3940, 2020 | 131 | 2020 |
A mono‐allelic bivalent chromatin domain controls tissue‐specific imprinting at Grb10 LA Sanz, S Chamberlain, JC Sabourin, A Henckel, T Magnuson, ... The EMBO journal 27 (19), 2523-2532, 2008 | 91 | 2008 |
Recognition of RNA by the S9. 6 antibody creates pervasive artifacts when imaging RNA: DNA hybrids JA Smolka, LA Sanz, SR Hartono, F Chédin Journal of Cell Biology 220 (6), e202004079, 2021 | 89 | 2021 |
Best practices for the visualization, mapping, and manipulation of R‐loops F Chédin, SR Hartono, LA Sanz, V Vanoosthuyse The EMBO Journal 40 (4), e106394, 2021 | 67 | 2021 |
EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos G Auclair, J Borgel, LA Sanz, J Vallet, S Guibert, M Dumas, P Cavelier, ... Genome research 26 (2), 192-202, 2016 | 67 | 2016 |
Ultra-deep coverage single-molecule R-loop footprinting reveals principles of R-loop formation M Malig, SR Hartono, JM Giafaglione, LA Sanz, F Chedin Journal of molecular biology 432 (7), 2271-2288, 2020 | 60 | 2020 |
CARM1 inhibition enables immunotherapy of resistant tumors by dual action on tumor cells and T cells S Kumar, Z Zeng, A Bagati, RE Tay, LA Sanz, SR Hartono, Y Ito, ... Cancer discovery 11 (8), 2050-2071, 2021 | 53 | 2021 |
RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2 C Alecki, V Chiwara, LA Sanz, D Grau, O Arias Pérez, EL Boulier, ... Nature communications 11 (1), 1781, 2020 | 53 | 2020 |
Genome-wide DNA demethylation in mammals LA Sanz, SK Kota, R Feil Genome biology 11 (3), 1-4, 2010 | 50 | 2010 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation P Richard, S Feng, YL Tsai, W Li, P Rinchetti, U Muhith, J Irizarry-Cole, ... Autophagy 17 (8), 1889-1906, 2021 | 37 | 2021 |
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma V Giuliani, MA Miller, CY Liu, SR Hartono, CA Class, CA Bristow, E Suzuki, ... Nature communications 12 (1), 4626, 2021 | 35 | 2021 |
Genomic patterns of transcription–replication interactions in mouse primary B cells CP St Germain, H Zhao, V Sinha, LA Sanz, F Chédin, JH Barlow Nucleic Acids Research 50 (4), 2051-2073, 2022 | 14 | 2022 |