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Motoki Takaku
Motoki Takaku
Verified email at und.edu
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Year
GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler
M Takaku, SA Grimm, T Shimbo, L Perera, R Menafra, HG Stunnenberg, ...
Genome biology 17, 1-16, 2016
1482016
GATA3 in breast cancer: tumor suppressor or oncogene?
M Takaku, SA Grimm, PA Wade
Gene expression 16 (4), 163, 2015
1152015
Reversing SKI–SMAD4-mediated suppression is essential for TH17 cell differentiation
S Zhang, M Takaku, L Zou, A Gu, W Chou, G Zhang, B Wu, Q Kong, ...
Nature 551 (7678), 105-109, 2017
1002017
CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language
L Snijders Blok, J Rousseau, J Twist, S Ehresmann, M Takaku, ...
Nature communications 9 (1), 4619, 2018
962018
GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network
M Takaku, SA Grimm, JD Roberts, K Chrysovergis, BD Bennett, P Myers, ...
Nature communications 9 (1), 1059, 2018
912018
Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities
Y Morozumi, Y Takizawa, M Takaku, H Kurumizaka
Nucleic acids research 37 (13), 4296-4307, 2009
762009
Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover
AB Adomas, SA Grimm, C Malone, M Takaku, JK Sims, PA Wade
BMC cancer 14, 1-14, 2014
652014
The CHD4-related syndrome: a comprehensive investigation of the clinical spectrum, genotype–phenotype correlations, and molecular basis
K Weiss, HP Lazar, A Kurolap, AF Martinez, T Paperna, L Cohen, ...
Genetics in Medicine 22 (2), 389-397, 2020
592020
Interaction of the pioneer transcription factor GATA3 with nucleosomes
H Tanaka, Y Takizawa, M Takaku, D Kato, Y Kumagawa, SA Grimm, ...
Nature communications 11 (1), 4136, 2020
562020
Rif1 promotes a repressive chromatin state to safeguard against endogenous retrovirus activation
P Li, L Wang, BD Bennett, J Wang, J Li, Y Qin, M Takaku, PA Wade, ...
Nucleic acids research 45 (22), 12723-12738, 2017
552017
Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51
M Takaku, T Kainuma, T Ishida‐Takaku, S Ishigami, H Suzuki, S Tashiro, ...
Genes to Cells 16 (4), 427-436, 2011
512011
Cancer-specific mutation of GATA3 disrupts the transcriptional regulatory network governed by Estrogen Receptor alpha, FOXA1 and GATA3
M Takaku, SA Grimm, B De Kumar, BD Bennett, PA Wade
Nucleic acids research 48 (9), 4756-4768, 2020
492020
DNA methylation in mice is influenced by genetics as well as sex and life experience
SA Grimm, T Shimbo, M Takaku, JW Thomas, S Auerbach, BD Bennett, ...
Nature communications 10 (1), 305, 2019
462019
GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
Y Takizawa, Y Qing, M Takaku, T Ishida, Y Morozumi, T Tsujita, T Kogame, ...
Nucleic acids research 38 (15), 5059-5074, 2010
432010
Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1
S Machida, M Takaku, M Ikura, J Sun, H Suzuki, W Kobayashi, ...
Scientific reports 4 (1), 4863, 2014
352014
Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome
S Machida, D Depierre, HC Chen, S Thenin-Houssier, G Petitjean, ...
Proceedings of the National Academy of Sciences 117 (12), 6822-6830, 2020
342020
The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction
M Katsura, T Tsuruga, O Date, T Yoshihara, M Ishida, Y Tomoda, ...
Nucleic acids research 37 (12), 3959-3968, 2009
322009
Purification of the human SMN–GEMIN2 complex and assessment of its stimulation of RAD51-mediated DNA recombination reactions
M Takaku, T Tsujita, N Horikoshi, Y Takizawa, Y Qing, K Hirota, M Ikura, ...
Biochemistry 50 (32), 6797-6805, 2011
312011
Vertebrate Spt2 is a novel nucleolar histone chaperone that assists in ribosomal DNA transcription
A Osakabe, H Tachiwana, M Takaku, T Hori, C Obuse, H Kimura, ...
Journal of cell science 126 (6), 1323-1332, 2013
292013
Recombination activator function of the novel RAD51-and RAD51B-binding protein, human EVL
M Takaku, S Machida, N Hosoya, S Nakayama, Y Takizawa, I Sakane, ...
Journal of biological chemistry 284 (21), 14326-14336, 2009
272009
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