Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes YS DeRose, G Wang, YC Lin, PS Bernard, SS Buys, MTW Ebbert, ... Nature medicine 17 (11), 1514-1520, 2011 | 1068 | 2011 |
Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells HC Tsai, H Li, L Van Neste, Y Cai, C Robert, FV Rassool, JJ Shin, ... Cancer cell 21 (3), 430-446, 2012 | 685 | 2012 |
Protective autophagy elicited by RAF→ MEK→ ERK inhibition suggests a treatment strategy for RAS-driven cancers CG Kinsey, SA Camolotto, AM Boespflug, KP Guillen, M Foth, A Truong, ... Nature medicine 25 (4), 620-627, 2019 | 552 | 2019 |
Plasma exosome microRNAs are indicative of breast cancer BN Hannafon, YD Trigoso, CL Calloway, YD Zhao, DH Lum, AL Welm, ... Breast cancer research 18, 1-14, 2016 | 541 | 2016 |
C/EBPα arrests cell proliferation through direct inhibition of Cdk2 and Cdk4 H Wang, P Iakova, M Wilde, A Welm, T Goode, WJ Roesler, ... Molecular cell 8 (4), 817-828, 2001 | 458 | 2001 |
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ... Cell 167 (1), 260-274. e22, 2016 | 444 | 2016 |
The lingering mysteries of metastatic recurrence in breast cancer AI Riggio, KE Varley, AL Welm British journal of cancer 124 (1), 13-26, 2021 | 378 | 2021 |
Understanding the bone in cancer metastasis J Fornetti, AL Welm, SA Stewart Journal of Bone and Mineral Research 33 (12), 2099-2113, 2018 | 373 | 2018 |
RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1 NA Timchenko, ZJ Cai, AL Welm, S Reddy, T Ashizawa, LT Timchenko Journal of Biological Chemistry 276 (11), 7820-7826, 2001 | 357 | 2001 |
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling DS Micalizzi, KL Christensen, P Jedlicka, RD Coletta, AE Barón, ... The Journal of clinical investigation 119 (9), 2678-2690, 2009 | 281 | 2009 |
Cell division and cell survival in the absence of survivin D Yang, A Welm, JM Bishop Proceedings of the National Academy of Sciences 101 (42), 15100-15105, 2004 | 262 | 2004 |
Patient-derived xenograft (PDX) models in basic and translational breast cancer research LE Dobrolecki, SD Airhart, DG Alferez, S Aparicio, F Behbod, ... Cancer and Metastasis Reviews 35, 547-573, 2016 | 252 | 2016 |
Patient‐derived models of human breast cancer: protocols for in vitro and in vivo applications in tumor biology and translational medicine YS DeRose, KM Gligorich, G Wang, A Georgelas, P Bowman, SJ Courdy, ... Current protocols in pharmacology 60 (1), 14.23. 1-14.23. 43, 2013 | 237 | 2013 |
A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis Q Feng, C Zhang, D Lum, JE Druso, B Blank, KF Wilson, A Welm, ... Nature communications 8 (1), 14450, 2017 | 227 | 2017 |
Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP L Shen, JM O’Shea, MR Kaadige, S Cunha, BR Wilde, AL Cohen, ... Proceedings of the National Academy of Sciences 112 (17), 5425-5430, 2015 | 221 | 2015 |
Lentiviral transduction of mammary stem cells for analysis of gene function during development and cancer BE Welm, GJP Dijkgraaf, AS Bledau, AL Welm, Z Werb Cell stem cell 2 (1), 90-102, 2008 | 215 | 2008 |
Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance N Takahashi, HY Chen, IS Harris, DG Stover, LM Selfors, RT Bronson, ... Cancer cell 33 (6), 985-1003. e7, 2018 | 209 | 2018 |
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition EL McCoy, R Iwanaga, P Jedlicka, NS Abbey, LA Chodosh, KA Heichman, ... The Journal of clinical investigation 119 (9), 2663-2677, 2009 | 207 | 2009 |
Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4 MA Powers, MM Fay, RE Factor, AL Welm, KS Ullman Cancer research 71 (16), 5579-5587, 2011 | 188 | 2011 |
The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans AL Welm, JB Sneddon, C Taylor, DSA Nuyten, MJ van de Vijver, ... Proceedings of the National Academy of Sciences 104 (18), 7570-7575, 2007 | 177 | 2007 |