Immunostimulatory DNA sequences necessary for effective intradermal gene immunization Y Sato, M Roman, H Tighe, D Lee, M Corr, MD Nguyen, GJ Silverman, ... Science 273 (5273), 352-354, 1996 | 1476 | 1996 |
CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. A Davies, DL Simmons, G Hale, RA Harrison, H Tighe, PJ Lachmann, ... The Journal of experimental medicine 170 (3), 637-654, 1989 | 731 | 1989 |
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. E Raz, H Tighe, Y Sato, M Corr, JA Dudler, M Roman, SL Swain, ... Proceedings of the National Academy of Sciences 93 (10), 5141-5145, 1996 | 708 | 1996 |
Gene vaccination with naked plasmid DNA: mechanism of CTL priming. M Corr, DJ Lee, DA Carson, H Tighe The Journal of experimental medicine 184 (4), 1555-1560, 1996 | 622 | 1996 |
Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice D Broide, J Schwarze, H Tighe, T Gifford, MD Nguyen, S Malek, ... The Journal of immunology 161 (12), 7054-7062, 1998 | 563 | 1998 |
Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity H Tighe, K Takabayashi, D Schwartz, G Van Nest, S Tuck, JJ Eiden, ... Journal of Allergy and Clinical Immunology 106 (1), 124-134, 2000 | 488 | 2000 |
Gene vaccination: plasmid DNA is more than just a blueprint H Tighe, M Corr, M Roman, E Raz Immunology Today 19 (2), 89-97, 1998 | 468 | 1998 |
The CAMPATH‐1 antigen (CDw52) G Hale, MQ Xia, HP Tighe, MJS Dyer, H Waldmann Tissue antigens 35 (3), 118-127, 1990 | 394 | 1990 |
T-cell control of Epstein–Barr virus-infected B cells is lost during P. falciparum malaria HC Whittle, J Brown, K Marsh, BM Greenwood, P Seidelin, H Tighe, ... Nature 312 (5993), 449-450, 1984 | 327 | 1984 |
In vivo priming by DNA injection occurs predominantly by antigen transfer M Corr, A von Damm, DJ Lee, H Tighe The Journal of Immunology 163 (9), 4721-4727, 1999 | 232 | 1999 |
Conjugation of protein to immunostimulatory DNA results in a rapid, long‐lasting and potent induction of cell‐mediated and humoral immunity H Tighe, K Takabayashi, D Schwartz, R Marsden, L Beck, J Corbeil, ... European journal of immunology 30 (7), 1939-1947, 2000 | 228 | 2000 |
CD4 monoclonal antibody pairs for immunosuppression and tolerance induction S Qin, S Cobbold, H Tighe, R Benjamin, H Waldmann European journal of immunology 17 (8), 1159-1165, 1987 | 211 | 1987 |
Costimulation provided by DNA immunization enhances antitumor immunity. M Corr, H Tighe, D Lee, J Dudler, M Trieu, DC Brinson, DA Carson Journal of immunology (Baltimore, Md.: 1950) 159 (10), 4999-5004, 1997 | 116 | 1997 |
Autoantibody production by severe combined immunodeficient mice reconstituted with synovial cells from rheumatoid arthritis patients H Tighe, GJ Silverman, F Kozin, R Tucker, R Gulizia, C Peebles, M Lotz, ... European journal of immunology 20 (8), 1843-1848, 1990 | 99 | 1990 |
Beneficial effect of monoclonal antibody to interleukin 2 receptor on activated T cells in rheumatoid arthritis. V Kyle, RJ Coughlan, H Tighe, H Waldmann, BL Hazleman Annals of the rheumatic diseases 48 (5), 428-429, 1989 | 95 | 1989 |
Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice. H Tighe, PP Chen, R Tucker, TJ Kipps, J Roudier, FR Jirik, DA Carson The Journal of experimental medicine 177 (1), 109-118, 1993 | 93 | 1993 |
Rheumatoid factor H Tighe Kelley's textbook of rheumatology, 151-160, 2001 | 91 | 2001 |
Human rheumatoid factor production is dependent on CD40 signaling and autoantigen D Kyburz, M Corr, DC Brinson, A Von Damm, H Tighe, DA Carson The Journal of Immunology 163 (6), 3116-3122, 1999 | 84 | 1999 |
Induction of antibodies to a kappa V region by gene immunization. A Watanabe, E Raz, H Kohsaka, H Tighe, SM Baird, TJ Kipps, DA Carson Journal of immunology (Baltimore, Md.: 1950) 151 (5), 2871-2876, 1993 | 76 | 1993 |
Inhibition of IgE antibody formation by plasmid DNA immunization is mediated by both CD4+ and CD8+ T cells DJ Lee, H Tighe, M Corr, M Roman, DA Carson, HL Spiegelberg, E Raz International archives of allergy and immunology 113 (1-3), 227-230, 1997 | 64 | 1997 |