| Using selective withdrawal to coat microparticles I Cohen, H Li, JL Hougland, M Mrksich, SR Nagel Science 292 (5515), 265-267, 2001 | 195 | 2001 |
| Functional identification of catalytic metal ion binding sites within RNA JL Hougland, AV Kravchuk, D Herschlag, JA Piccirilli PLoS biology 3 (9), e277, 2005 | 86 | 2005 |
| Identification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivities JL Hougland, KA Hicks, HL Hartman, RA Kelly, TJ Watt, CA Fierke Journal of molecular biology 395 (1), 176-190, 2010 | 77 | 2010 |
| Identification of a novel class of farnesylation targets by structure-based modeling of binding specificity N London, CL Lamphear, JL Hougland, CA Fierke, O Schueler-Furman PLoS computational biology 7 (10), e1002170, 2011 | 68 | 2011 |
| How the group I intron works: A case study of RNA structure and function JL Hougland, JA Piccirilli, M Forconi, J Lee, D Herschlag Cold Spring Harbor Monograph Series 43, 133, 2006 | 68 | 2006 |
| Structure–Activity Analysis of Human Ghrelin O-Acyltransferase Reveals Chemical Determinants of Ghrelin Selectivity and Acyl Group Recognition JE Darling, F Zhao, RJ Loftus, LM Patton, RA Gibbs, JL Hougland Biochemistry 54 (4), 1100-1110, 2015 | 64 | 2015 |
| Ghrelin signaling: GOAT and GHS-R1a take a LEAP in complexity A Abizaid, JL Hougland Trends in Endocrinology & Metabolism 31 (2), 107-117, 2020 | 61 | 2020 |
| Context-dependent substrate recognition by protein farnesyltransferase JL Hougland, CL Lamphear, SA Scott, RA Gibbs, CA Fierke Biochemistry 48 (8), 1691-1701, 2009 | 52 | 2009 |
| Efficient farnesylation of an extended C-terminal C (x) 3X sequence motif expands the scope of the prenylated proteome MJ Blanden, KF Suazo, ER Hildebrandt, DS Hardgrove, M Patel, ... Journal of Biological Chemistry 293 (8), 2770-2785, 2018 | 48 | 2018 |
| A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase JE Darling, EP Prybolsky, M Sieburg, JL Hougland Analytical biochemistry 437 (1), 68-76, 2013 | 45 | 2013 |
| Simultaneous site-specific dual protein labeling using protein prenyltransferases Y Zhang, MJ Blanden, C Sudheer, SA Gangopadhyay, M Rashidian, ... Bioconjugate chemistry 26 (12), 2542-2553, 2015 | 42 | 2015 |
| The RNA world JL Hougland, JA Piccirilli, M Forconi, J Lee, D Herschlag Cold Spring Harbor Laboratory Press, 2006 | 37 | 2006 |
| Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into … KR McGovern-Gooch, NS Mahajani, A Garagozzo, AJ Schramm, ... Biochemistry 56 (7), 919-931, 2017 | 33 | 2017 |
| Synthesis and screening of a CaaL peptide library versus FTase reveals a surprising number of substrates AJ Krzysiak, AV Aditya, JL Hougland, CA Fierke, RA Gibbs Bioorganic & medicinal chemistry letters 20 (2), 767-770, 2010 | 33 | 2010 |
| Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling JL Hougland Biochemical Society Transactions 47 (1), 169-178, 2019 | 32 | 2019 |
| The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation MB Campaña, FJ Irudayanathan, TR Davis, KR McGovern-Gooch, ... Journal of Biological Chemistry 294 (39), 14166-14174, 2019 | 28 | 2019 |
| Expansion of protein farnesyltransferase specificity using “tunable” active site interactions: development of bioengineered prenylation pathways JL Hougland, SA Gangopadhyay, CA Fierke Journal of Biological Chemistry 287 (45), 38090-38100, 2012 | 25 | 2012 |
| A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups F Zhao, JE Darling, RA Gibbs, JL Hougland Bioorganic & Medicinal Chemistry Letters 25 (14), 2800-2803, 2015 | 22 | 2015 |
| An overview of ghrelin O-acyltransferase inhibitors: a literature and patent review for 2010-2019 JE Moose, KA Leets, NA Mate, JD Chisholm, JL Hougland Expert opinion on therapeutic patents 30 (8), 581-593, 2020 | 21 | 2020 |
| Protein farnesyltransferase catalyzes unanticipated farnesylation and geranylgeranylation of shortened target sequences S Ashok, ER Hildebrandt, CS Ruiz, DS Hardgrove, DW Coreno, ... Biochemistry 59 (11), 1149-1162, 2020 | 21 | 2020 |
Carol FierkeTexas A&M UniversityVerified email at tamu.edu
