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Marion van den Bosch
Marion van den Bosch
Verified email at bristol.ac.uk
Title
Cited by
Cited by
Year
Integrin αIIbβ3 outside-in signaling
TN Durrant, MT van den Bosch, I Hers
Blood, The Journal of the American Society of Hematology 130 (14), 1607-1619, 2017
2532017
Coordinated membrane ballooning and procoagulant spreading in human platelets
EO Agbani, MTJ van den Bosch, ED Brown, CM Williams, NJA Mattheij, ...
Circulation 132 (15), 1414-1424, 2015
1652015
Dual regulation of glycogen synthase kinase 3 (GSK3) α/β by protein kinase C (PKC) α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in …
SF Moore, MTJ van den Bosch, RW Hunter, K Sakamoto, AW Poole, ...
Journal of Biological Chemistry 288 (6), 3918-3928, 2013
1632013
Procoagulant and inflammatory response of virus‐infected monocytes
JJM Bouwman, FLJ Visseren, MC Bosch, KP Bouter, RJA Diepersloot
European journal of clinical investigation 32 (10), 759-766, 2002
1002002
Platelet-associated matrix metalloproteinases regulate thrombus formation and exert local collagenolytic activity
TG Mastenbroek, MAH Feijge, RMW Kremers, MTJ van den Bosch, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2554-2561, 2015
492015
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling
J Lam, M van den Bosch, J Wegrzyn, J Parker, R Ibrahim, K Slowski, ...
Nature communications 9 (1), 2418, 2018
362018
Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis
EO Agbani, CM Williams, Y Li, MTJ van den Bosch, SF Moore, A Mauroux, ...
JCI insight 3 (10), 2018
322018
Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4–deficient platelets
MT Harper, MT van den Bosch, I Hers, AW Poole
Blood, The Journal of the American Society of Hematology 125 (19), 3034-3036, 2015
322015
Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX
E Marcolino, YH Siddiqui, M van den Bosch, AW Poole, PS Jayaraman, ...
Oncogenesis 9 (2), 10, 2020
262020
Cytohesin‐2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP‐ribosylation factor 6
MTJ Van Den Bosch, AW Poole, I Hers
Journal of Thrombosis and Haemostasis 12 (5), 726-735, 2014
242014
Loss of the mitochondrial kinase PINK1 does not alter platelet function
TG Walsh, MTJ van den Bosch, KE Lewis, CM Williams, AW Poole
Scientific Reports 8 (1), 14377, 2018
232018
Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology
BJ Telford, S Yahyanejad, T de Gunst, HC den Boer, RM Vos, M Stegink, ...
Oncotarget 12 (5), 422, 2021
162021
All-trans retinoic acid impairs platelet function and thrombus formation and inhibits protein kinase CßI/δ phosphorylation
Q Luo, G Wei, X Wang, X Xu, W Ju, Z Li, EE Gardiner, RK Andrews, ...
Thrombosis and Haemostasis 119 (10), 1655-1664, 2019
122019
Absence of platelet phenotype in mice lacking the motor protein myosin Va
MT Harper, MTJ Van Den Bosch, I Hers, AW Poole
PLoS One 8 (1), e53239, 2013
112013
Epigenetic Regulation of F2RL3 Associates With Myocardial Infarction and Platelet Function
LJ Corbin, SJ White, AE Taylor, CM Williams, K Taylor, MT van den Bosch, ...
Circulation research 130 (3), 384-400, 2022
92022
Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic
MTJ van den Bosch, S Yahyanejad, MF Alemdehy, BJ Telford, T de Gunst, ...
Molecular Therapy-Nucleic Acids 23, 1161-1171, 2021
82021
Phase I/Ib study with INT-1B3, a novel LNP-formulated micro-RNA (miR-193a-3p mimic) therapeutic for patients with advanced solid cancer.
N Kotecki, F Opdam, D Robbrecht, M Strijbos, K Kroon, M Janicot, ...
Journal of Clinical Oncology 39 (15_suppl), TPS2666-TPS2666, 2021
62021
Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease
LJ Corbin, AE Taylor, SJ White, CM Williams, K Taylor, MT den Bosch, ...
bioRxiv, 473728, 2018
22018
Wilms' Tumor 1 Functions As a Tumor Suppressor to Suppress FLT3-STAT Signaling and Epigenetic Remodeling in Acute Myeloid Leukemia (CALGB 8461, 9665 and 20202; Alliance)
D Buelow, X Yang, D Nicolet, K Mrózek, K Krowiorz, R Bhayadia, ...
Blood 142 (Supplement 1), 4126-4126, 2023
2023
P422: TARGETING THE WT1MUT-MIR-193A TRANSCRIPTIONAL AXIS WITH INT-1B3, A NOVEL LIPID NANOPARTICLE-FORMULATED MIR-193A-3P MIMIC IN ACUTE MYELOID LEUKEMIA
X Yang, K Krowiorz, D Buelow, R Bhayadia, J Kohlschmidt, D Nicolet, ...
HemaSphere 7 (S3), e43178c6, 2023
2023
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