Integrin αIIbβ3 outside-in signaling TN Durrant, MT van den Bosch, I Hers Blood, The Journal of the American Society of Hematology 130 (14), 1607-1619, 2017 | 253 | 2017 |
Coordinated membrane ballooning and procoagulant spreading in human platelets EO Agbani, MTJ van den Bosch, ED Brown, CM Williams, NJA Mattheij, ... Circulation 132 (15), 1414-1424, 2015 | 165 | 2015 |
Dual regulation of glycogen synthase kinase 3 (GSK3) α/β by protein kinase C (PKC) α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in … SF Moore, MTJ van den Bosch, RW Hunter, K Sakamoto, AW Poole, ... Journal of Biological Chemistry 288 (6), 3918-3928, 2013 | 163 | 2013 |
Procoagulant and inflammatory response of virus‐infected monocytes JJM Bouwman, FLJ Visseren, MC Bosch, KP Bouter, RJA Diepersloot European journal of clinical investigation 32 (10), 759-766, 2002 | 100 | 2002 |
Platelet-associated matrix metalloproteinases regulate thrombus formation and exert local collagenolytic activity TG Mastenbroek, MAH Feijge, RMW Kremers, MTJ van den Bosch, ... Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2554-2561, 2015 | 49 | 2015 |
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling J Lam, M van den Bosch, J Wegrzyn, J Parker, R Ibrahim, K Slowski, ... Nature communications 9 (1), 2418, 2018 | 36 | 2018 |
Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis EO Agbani, CM Williams, Y Li, MTJ van den Bosch, SF Moore, A Mauroux, ... JCI insight 3 (10), 2018 | 32 | 2018 |
Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4–deficient platelets MT Harper, MT van den Bosch, I Hers, AW Poole Blood, The Journal of the American Society of Hematology 125 (19), 3034-3036, 2015 | 32 | 2015 |
Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX E Marcolino, YH Siddiqui, M van den Bosch, AW Poole, PS Jayaraman, ... Oncogenesis 9 (2), 10, 2020 | 26 | 2020 |
Cytohesin‐2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP‐ribosylation factor 6 MTJ Van Den Bosch, AW Poole, I Hers Journal of Thrombosis and Haemostasis 12 (5), 726-735, 2014 | 24 | 2014 |
Loss of the mitochondrial kinase PINK1 does not alter platelet function TG Walsh, MTJ van den Bosch, KE Lewis, CM Williams, AW Poole Scientific Reports 8 (1), 14377, 2018 | 23 | 2018 |
Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology BJ Telford, S Yahyanejad, T de Gunst, HC den Boer, RM Vos, M Stegink, ... Oncotarget 12 (5), 422, 2021 | 16 | 2021 |
All-trans retinoic acid impairs platelet function and thrombus formation and inhibits protein kinase CßI/δ phosphorylation Q Luo, G Wei, X Wang, X Xu, W Ju, Z Li, EE Gardiner, RK Andrews, ... Thrombosis and Haemostasis 119 (10), 1655-1664, 2019 | 12 | 2019 |
Absence of platelet phenotype in mice lacking the motor protein myosin Va MT Harper, MTJ Van Den Bosch, I Hers, AW Poole PLoS One 8 (1), e53239, 2013 | 11 | 2013 |
Epigenetic Regulation of F2RL3 Associates With Myocardial Infarction and Platelet Function LJ Corbin, SJ White, AE Taylor, CM Williams, K Taylor, MT van den Bosch, ... Circulation research 130 (3), 384-400, 2022 | 9 | 2022 |
Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic MTJ van den Bosch, S Yahyanejad, MF Alemdehy, BJ Telford, T de Gunst, ... Molecular Therapy-Nucleic Acids 23, 1161-1171, 2021 | 8 | 2021 |
Phase I/Ib study with INT-1B3, a novel LNP-formulated micro-RNA (miR-193a-3p mimic) therapeutic for patients with advanced solid cancer. N Kotecki, F Opdam, D Robbrecht, M Strijbos, K Kroon, M Janicot, ... Journal of Clinical Oncology 39 (15_suppl), TPS2666-TPS2666, 2021 | 6 | 2021 |
Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease LJ Corbin, AE Taylor, SJ White, CM Williams, K Taylor, MT den Bosch, ... bioRxiv, 473728, 2018 | 2 | 2018 |
Wilms' Tumor 1 Functions As a Tumor Suppressor to Suppress FLT3-STAT Signaling and Epigenetic Remodeling in Acute Myeloid Leukemia (CALGB 8461, 9665 and 20202; Alliance) D Buelow, X Yang, D Nicolet, K Mrózek, K Krowiorz, R Bhayadia, ... Blood 142 (Supplement 1), 4126-4126, 2023 | | 2023 |
P422: TARGETING THE WT1MUT-MIR-193A TRANSCRIPTIONAL AXIS WITH INT-1B3, A NOVEL LIPID NANOPARTICLE-FORMULATED MIR-193A-3P MIMIC IN ACUTE MYELOID LEUKEMIA X Yang, K Krowiorz, D Buelow, R Bhayadia, J Kohlschmidt, D Nicolet, ... HemaSphere 7 (S3), e43178c6, 2023 | | 2023 |