| Cancer-associated IDH1 promotes growth and resistance to targeted therapies in the absence of mutation AE Calvert, A Chalastanis, Y Wu, LA Hurley, FM Kouri, Y Bi, M Kachman, ... Cell reports 19 (9), 1858-1873, 2017 | 203 | 2017 |
| Measurement of local permeability at subcellular level in cell models of agonist-and ventilator-induced lung injury O Dubrovskyi, AA Birukova, KG Birukov Laboratory investigation 93 (2), 254-263, 2013 | 158 | 2013 |
| Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions N Zebda, O Dubrovskyi, KG Birukov Microvascular research 83 (1), 71-81, 2012 | 149 | 2012 |
| Design of SARS-CoV-2 PLpro inhibitors for COVID-19 antiviral therapy leveraging binding cooperativity Z Shen, K Ratia, L Cooper, D Kong, H Lee, Y Kwon, Y Li, S Alqarni, ... Journal of medicinal chemistry 65 (4), 2940-2955, 2021 | 123 | 2021 |
| Patient-derived tumor xenografts are susceptible to formation of human lymphocytic tumors G Bondarenko, A Ugolkov, S Rohan, P Kulesza, O Dubrovskyi, D Gursel, ... Neoplasia 17 (9), 735-741, 2015 | 96 | 2015 |
| Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1 AA Birukova, J Xing, P Fu, B Yakubov, O Dubrovskyi, JA Fortune, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 299 (5 …, 2010 | 86 | 2010 |
| GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids AA Birukova, PA Singleton, G Gawlak, X Tian, T Mirzapoiazova, ... Molecular biology of the cell 25 (13), 2006-2016, 2014 | 63 | 2014 |
| p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator-induced lung injury AA Birukova, N Zebda, I Cokic, P Fu, T Wu, O Dubrovskyi, KG Birukov Experimental cell research 317 (6), 859-872, 2011 | 56 | 2011 |
| VE‐cadherin trans‐interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost AA Birukova, Y Tian, O Dubrovskyi, N Zebda, N Sarich, X Tian, Y Wang, ... Journal of cellular physiology 227 (10), 3405-3416, 2012 | 55 | 2012 |
| Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM) X Xu, Y Cai, Y Wei, F Donate, J Juarez, G Parry, L Chen, EJ Meehan, ... PloS one 9 (1), e85349, 2014 | 49 | 2014 |
| Afadin controls p120‐catenin–ZO‐1 interactions leading to endothelial barrier enhancement by oxidized phospholipids AA Birukova, P Fu, T Wu, O Dubrovskyi, N Sarich, V Poroyko, KG Birukov Journal of cellular physiology 227 (5), 1883-1890, 2012 | 49 | 2012 |
| Melanoma cells block PEDF production in fibroblasts to induce the tumor-promoting phenotype of cancer-associated fibroblasts NG Nwani, ML Deguiz, B Jimenez, E Vinokour, O Dubrovskyi, A Ugolkov, ... Cancer research 76 (8), 2265-2276, 2016 | 46 | 2016 |
| Identification of HDAC6‐Selective Inhibitors of Low Cancer Cell Cytotoxicity IN Gaisina, W Tueckmantel, A Ugolkov, S Shen, J Hoffen, O Dubrovskyi, ... ChemMedChem 11 (1), 81-92, 2016 | 43 | 2016 |
| Coactivation of estrogen receptor and IKKβ induces a dormant metastatic phenotype in ER-positive breast cancer L El-Shennawy, O Dubrovskyi, I Kastrati, JM Danes, Y Zhang, ... Cancer research 78 (4), 974-984, 2018 | 39 | 2018 |
| Potent, novel SARS-CoV-2 PLpro inhibitors block viral replication in monkey and human cell cultures Z Shen, K Ratia, L Cooper, D Kong, H Lee, Y Kwon, Y Li, S Alqarni, ... BioRxiv, 2021.02. 13.431008, 2021 | 29 | 2021 |
| 9-ING-41, a small-molecule glycogen synthase kinase-3 inhibitor, is active in neuroblastoma AV Ugolkov, GI Bondarenko, O Dubrovskyi, AP Berbegall, S Navarro, ... Anti-cancer drugs 29 (8), 717-724, 2018 | 26 | 2018 |
| Phosphorylation of Gβ is crucial for efficient chemotropism in yeast R DeFlorio, ME Brett, N Waszczak, E Apollinari, MV Metodiev, ... Journal of cell science 126 (14), 2997-3009, 2013 | 23 | 2013 |
| XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer DR Principe, R Xiong, Y Li, TND Pham, SD Kamath, O Dubrovskyi, ... Proceedings of the National Academy of Sciences 119 (4), e2116764119, 2022 | 21 | 2022 |
| Novel pyrrolopyridone bromodomain and extra-terminal motif (BET) inhibitors effective in endocrine-resistant ER+ breast cancer with acquired resistance to fulvestrant and … Y Li, J Zhao, LM Gutgesell, Z Shen, K Ratia, K Dye, O Dubrovskyi, H Zhao, ... Journal of medicinal chemistry 63 (13), 7186-7210, 2020 | 19 | 2020 |
| Identification of paxilin domains interacting with β-catenin O Dubrovskyi, X Tian, V Poroyko, B Yakubov, AA Birukova, KG Birukov FEBS letters 586 (16), 2294-2299, 2012 | 18 | 2012 |
Metodi V. MetodievSchool of Life Sciences, University of Essex, United KingdomVerified email at essex.ac.uk
