| DNA mismatches reveal conformational penalties in protein–DNA recognition A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ... Nature 587 (7833), 291-296, 2020 | 87 | 2020 |
| 2′-O-Methylation can increase the abundance and lifetime of alternative RNA conformational states H Abou Assi, AK Rangadurai, H Shi, B Liu, MC Clay, K Erharter, C Kreutz, ... Nucleic acids research 48 (21), 12365-12379, 2020 | 77 | 2020 |
| Characterizing micro-to-millisecond chemical exchange in nucleic acids using off-resonance R1ρ relaxation dispersion A Rangadurai, ES Szymaski, IJ Kimsey, H Shi, HM Al-Hashimi Progress in nuclear magnetic resonance spectroscopy 112, 55-102, 2019 | 65 | 2019 |
| Insights into Watson–Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m1A B Sathyamoorthy, H Shi, H Zhou, Y Xue, A Rangadurai, DK Merriman, ... Nucleic acids research 45 (9), 5586-5601, 2017 | 65 | 2017 |
| Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction H Shi, A Rangadurai, H Abou Assi, R Roy, DA Case, D Herschlag, ... Nature communications 11 (1), 5531, 2020 | 56 | 2020 |
| NMR Chemical Exchange Measurements Reveal That N6-Methyladenosine Slows RNA Annealing H Shi, B Liu, F Nussbaumer, A Rangadurai, C Kreutz, HM Al-Hashimi Journal of the American Chemical Society 141 (51), 19988-19993, 2019 | 52 | 2019 |
| Developments in solution-state NMR yield broader and deeper views of the dynamic ensembles of nucleic acids B Liu, H Shi, HM Al-Hashimi Current opinion in structural biology 70, 16-25, 2021 | 47 | 2021 |
| Atomic structures of excited state A–T Hoogsteen base pairs in duplex DNA by combining NMR relaxation dispersion, mutagenesis, and chemical shift calculations H Shi, MC Clay, A Rangadurai, B Sathyamoorthy, DA Case, ... Journal of biomolecular NMR 70, 229-244, 2018 | 37 | 2018 |
| Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA? A Rangadurai, H Zhou, DK Merriman, N Meiser, B Liu, H Shi, ... Nucleic acids research 46 (20), 11099-11114, 2018 | 30 | 2018 |
| A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions B Liu, H Shi, A Rangadurai, F Nussbaumer, CC Chu, KA Erharter, ... Nature communications 12 (1), 5201, 2021 | 29 | 2021 |
| Extending the sensitivity of CEST NMR spectroscopy to micro‐to‐millisecond dynamics in nucleic acids using high‐power radio‐frequency fields A Rangadurai, H Shi, HM Al‐Hashimi Angewandte Chemie International Edition 59 (28), 11262-11266, 2020 | 29 | 2020 |
| Improved genome editing by an engineered CRISPR-Cas12a E Ma, K Chen, H Shi, EC Stahl, B Adler, M Trinidad, J Liu, K Zhou, J Ye, ... Nucleic Acids Research 50 (22), 12689-12701, 2022 | 25 | 2022 |
| Probing conformational transitions towards mutagenic Watson–Crick-like G·T mismatches using off-resonance sugar carbon R1ρ relaxation dispersion A Rangadurai, ES Szymanski, I Kimsey, H Shi, HM Al-Hashimi Journal of Biomolecular NMR 74, 457-471, 2020 | 25 | 2020 |
| Hoogsteen base pairs increase the susceptibility of double-stranded DNA to cytotoxic damage Y Xu, A Manghrani, B Liu, H Shi, U Pham, A Liu, HM Al-Hashimi Journal of Biological Chemistry 295 (47), 15933-15947, 2020 | 22 | 2020 |
| Increasing the length of poly-pyrimidine bulges broadens RNA conformational ensembles with minimal impact on stacking energetics DK Merriman, J Yuan, H Shi, A Majumdar, D Herschlag, HM Al-Hashimi Rna 24 (10), 1363-1376, 2018 | 20 | 2018 |
| Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem–loop RNAs and their implications for functional cellular assays ML Kelly, CC Chu, H Shi, LR Ganser, HP Bogerd, K Huynh, Y Hou, ... RNA 27 (1), 12-26, 2021 | 17 | 2021 |
| Direct evidence for (G) O6··· H2-N4 (C)+ hydrogen bonding in transient G (syn)-C+ and G (syn)-m5C+ Hoogsteen base pairs in duplex DNA from cytosine amino nitrogen off-resonance … A Rangadurai, J Kremser, H Shi, C Kreutz, HM Al-Hashimi Journal of magnetic resonance 308, 106589, 2019 | 16 | 2019 |
| Revealing AT and GC Hoogsteen base pairs in stressed protein-bound duplex DNA H Shi, IJ Kimsey, S Gu, HF Liu, U Pham, MA Schumacher, HM Al-Hashimi Nucleic acids research 49 (21), 12540-12555, 2021 | 14 | 2021 |
| Probing the hydrogen-bonding environment of individual bases in DNA duplexes with isotope-edited infrared spectroscopy RJ Fick, AY Liu, F Nussbaumer, C Kreutz, A Rangadurai, Y Xu, ... The Journal of Physical Chemistry B 125 (28), 7613-7627, 2021 | 14 | 2021 |
| Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy DW Conroy, Y Xu, H Shi, N Gonzalez Salguero, RN Purusottam, ... Proceedings of the National Academy of Sciences 119 (30), e2200681119, 2022 | 12 | 2022 |
Hashim M Al-HashimiColumbia UniversityVerified email at cumc.columbia.edu
