The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance FA Siebzehnrubl, DJ Silver, B Tugertimur, LP Deleyrolle, D Siebzehnrubl, ... EMBO molecular medicine 5 (8), 1196-1212, 2013 | 409 | 2013 |
Overcoming macrophage-mediated axonal dieback following CNS injury SA Busch, KP Horn, DJ Silver, J Silver Journal of Neuroscience 29 (32), 9967-9976, 2009 | 258 | 2009 |
Chronic enhancement of the intrinsic growth capacity of sensory neurons combined with the degradation of inhibitory proteoglycans allows functional regeneration of sensory … MP Steinmetz, KP Horn, VJ Tom, JH Miller, SA Busch, D Nair, DJ Silver, ... Journal of Neuroscience 25 (35), 8066-8076, 2005 | 236 | 2005 |
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion B Otvos, DJ Silver, EE Mulkearns-Hubert, AG Alvarado, SM Turaga, ... Stem cells 34 (8), 2026-2039, 2016 | 220 | 2016 |
Glioblastoma cancer stem cells evade innate immune suppression of self-renewal through reduced TLR4 expression AG Alvarado, PS Thiagarajan, EE Mulkearns-Hubert, DJ Silver, JS Hale, ... Cell stem cell 20 (4), 450-461. e4, 2017 | 173 | 2017 |
Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner D Bayik, Y Zhou, C Park, C Hong, D Vail, DJ Silver, A Lauko, G Roversi, ... Cancer discovery 10 (8), 1210-1225, 2020 | 155 | 2020 |
Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment DJ Silver, FA Siebzehnrubl, MJ Schildts, AT Yachnis, GM Smith, AA Smith, ... Journal of Neuroscience 33 (39), 15603-15617, 2013 | 136 | 2013 |
The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors LN Tumey, D Bom, B Huck, E Gleason, J Wang, D Silver, K Brunden, ... Bioorganic & medicinal chemistry letters 15 (2), 277-281, 2005 | 104 | 2005 |
The intersection of cancer, cancer stem cells, and the immune system: therapeutic opportunities DJ Silver, M Sinyuk, MA Vogelbaum, MS Ahluwalia, JD Lathia Neuro-oncology 18 (2), 153-159, 2015 | 103 | 2015 |
Contributions of chondroitin sulfate proteoglycans to neurodevelopment, injury, and cancer DJ Silver, J Silver Current opinion in neurobiology 27, 171-178, 2014 | 89 | 2014 |
Functional subclone profiling for prediction of treatment-induced intratumor population shifts and discovery of rational drug combinations in human glioblastoma R Reinartz, S Wang, S Kebir, DJ Silver, A Wieland, T Zheng, M Küpper, ... Clinical cancer research 23 (2), 562-574, 2017 | 79 | 2017 |
Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models JKT Dermawan, M Hitomi, DJ Silver, Q Wu, P Sandlesh, AE Sloan, ... Cancer research 76 (8), 2432-2442, 2016 | 72 | 2016 |
Detection of primary cilia in human glioblastoma MR Sarkisian, D Siebzehnrubl, L Hoang-Minh, L Deleyrolle, DJ Silver, ... Journal of neuro-oncology 117, 15-24, 2014 | 72 | 2014 |
ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells A Jimenez-Pascual, JS Hale, A Kordowski, J Pugh, DJ Silver, D Bayik, ... Cancer discovery 9 (11), 1574-1589, 2019 | 60 | 2019 |
The evolution of the cancer stem cell state in glioblastoma: emerging insights into the next generation of functional interactions K Mitchell, K Troike, DJ Silver, JD Lathia Neuro-oncology 23 (2), 199-213, 2021 | 59 | 2021 |
Common astrocytic programs during brain development, injury and cancer DJ Silver, DA Steindler Trends in neurosciences 32 (6), 303-311, 2009 | 55 | 2009 |
Revealing the glioma cancer stem cell interactome, one niche at a time DJ Silver, JD Lathia The Journal of pathology 244 (3), 260-264, 2018 | 45 | 2018 |
Metabolic heterogeneity and adaptability in brain tumors CE Badr, DJ Silver, FA Siebzehnrubl, LP Deleyrolle Cellular and Molecular Life Sciences 77, 5101-5119, 2020 | 40 | 2020 |
Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling AG Alvarado, SM Turaga, P Sathyan, EE Mulkearns-Hubert, B Otvos, ... Neuro-oncology 18 (5), 656-666, 2016 | 39 | 2016 |
Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists MJ Robarge, DC Bom, LN Tumey, N Varga, E Gleason, D Silver, J Song, ... Bioorganic & medicinal chemistry letters 15 (6), 1749-1753, 2005 | 39 | 2005 |