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Aloke K Dutta
Aloke K Dutta
Verified email at wayne.edu
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Year
Discovery of 4-(4-(2-((5-Hydroxy-1, 2, 3, 4-tetrahydronaphthalen-2-yl)(propyl) amino) ethyl) piperazin-1-yl) quinolin-8-ol and its analogues as highly potent dopamine D2/D3 …
B Ghosh, T Antonio, MEA Reith, AK Dutta
Journal of medicinal chemistry 53 (5), 2114-2125, 2010
962010
Interaction of cocaine‐, benztropine‐, and GBR12909‐like compounds with wild‐type and mutant human dopamine transporters: molecular features that differentially determine …
KC Schmitt, J Zhen, P Kharkar, M Mishra, N Chen, AK Dutta, MEA Reith
Journal of neurochemistry 107 (4), 928-940, 2008
842008
Development of (S)-N6-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and Its Analogue as a D3 …
B Ghosh, T Antonio, J Zhen, P Kharkar, MEA Reith, AK Dutta
Journal of medicinal chemistry 53 (3), 1023-1037, 2010
822010
Dopamine transporter as target for drug development of cocaine dependence medications
AK Dutta, S Zhang, R Kolhatkar, MEA Reith
European journal of pharmacology 479 (1-3), 93-106, 2003
802003
Structure− activity relationship studies of novel 4-[2-[bis (4-fluorophenyl) methoxy] ethyl]-1-(3-phenylpropyl) piperidine analogs: synthesis and biological evaluation at the …
AK Dutta, C Xu, MEA Reith
Journal of medicinal chemistry 39 (3), 749-756, 1996
791996
Synthesis and biological characterization of novel hybrid 7-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5, 6, 7, 8-tetrahydro-naphthalen-2-ol and their heterocyclic …
AK Dutta, SK Venkataraman, XS Fei, R Kolhatkar, S Zhang, MEA Reith
Bioorganic & medicinal chemistry 12 (16), 4361-4373, 2004
662004
Novel D3 dopamine receptor‐preferring agonist D‐264: Evidence of neuroprotective property in Parkinson's disease animal models induced by 1‐methyl‐4‐phenyl‐1, 2, 3, 6 …
C Li, S Biswas, X Li, AK Dutta, W Le
Journal of neuroscience research 88 (11), 2513-2523, 2010
652010
Further structure–activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl) ethyl] propylamino}-5, 6, 7, 8-tetrahydronaphthalen-2-ol analogues: identification of a …
S Biswas, S Zhang, F Fernandez, B Ghosh, J Zhen, E Kuzhikandathil, ...
Journal of medicinal chemistry 51 (1), 101-117, 2008
652008
Structure–Activity Relationship Study of N6-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues …
M Johnson, T Antonio, MEA Reith, AK Dutta
Journal of medicinal chemistry 55 (12), 5826-5840, 2012
642012
Highly selective, novel analogs of 4-[2-(diphenylmethoxy) ethyl]-1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity …
AK Dutta, LL Coffey, MEA Reith
Journal of medicinal chemistry 40 (1), 35-43, 1997
631997
Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl) ethyl] propylamino}-5, 6, 7, 8-tetrahydronaphthalen-2-ol: identification of highly potent and selective …
S Biswas, S Hazeldine, B Ghosh, I Parrington, E Kuzhikandathil, ...
Journal of medicinal chemistry 51 (10), 3005-3019, 2008
612008
Multi-objective optimization of hybrid laminates subjected to transverse impact
G Sandeep, D Chakraborty, A Dutta
Composite Structures 73 (3), 360-369, 2006
582006
Inhibition of alpha-synuclein aggregation by multifunctional dopamine agonists assessed by a novel in vitro assay and an in vivo Drosophila synucleinopathy model
D Yedlapudi, GS Joshi, D Luo, SV Todi, AK Dutta
Scientific reports 6 (1), 38510, 2016
572016
A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors
AK Dutta, XS Fei, MEA Reith
Bioorganic & medicinal chemistry letters 12 (4), 619-622, 2002
562002
Positional Importance of the Nitrogen Atom in Novel Piperidine Analogues of GBR 12909: Affinity and Selectivity for the Dopamine Transporter.
AK Dutta, PC Meltzer, BK Madras
ChemInform 25 (16), no-no, 1994
561994
Triple reuptake inhibitors as potential next-generation antidepressants: a new hope?
H Sharma, S Santra, A Dutta
Future medicinal chemistry 7 (17), 2385-2406, 2015
512015
Potent and selective ligands for the dopamine transporter (DAT): Structure− activity relationship studies of novel 4-[2-(diphenylmethoxy) ethyl]-1-(3-phenylpropyl) piperidine …
AK Dutta, LL Coffey, MEA Reith
Journal of medicinal chemistry 41 (5), 699-705, 1998
511998
α-Synuclein aggregation modulation: an emerging approach for the treatment of Parkinson's disease
SK Singh, A Dutta, G Modi
Future medicinal chemistry 9 (10), 1039-1053, 2017
492017
Magnetic and electric properties of antimony selenide (Sb2Se3) crystals
BR Chakraborty, B Ray, R Bhattacharya, AK Dutta
Journal of Physics and Chemistry of Solids 41 (8), 913-917, 1980
491980
Dual incorporation of photoaffinity ligands on dopamine transporters implicates proximity of labeled domains
RA Vaughan, JD Gaffaney, JR Lever, MEA Reith, AK Dutta
Molecular Pharmacology 59 (5), 1157-1164, 2001
482001
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