RNA splicing by the spliceosome ME Wilkinson, C Charenton, K Nagai Annual review of biochemistry 89, 359-388, 2020 | 494 | 2020 |
Cryo-EM structure of the spliceosome immediately after branching WP Galej, ME Wilkinson, SM Fica, C Oubridge, AJ Newman, K Nagai Nature 537 (7619), 197-201, 2016 | 242 | 2016 |
Structure of a spliceosome remodelled for exon ligation SM Fica, C Oubridge, WP Galej, ME Wilkinson, XC Bai, AJ Newman, ... Nature 542 (7641), 377-380, 2017 | 173 | 2017 |
Mechanism of 5ʹ splice site transfer for human spliceosome activation C Charenton, ME Wilkinson, K Nagai Science 364 (6438), 362-367, 2019 | 124 | 2019 |
Spacer capture and integration by a type IF Cas1–Cas2-3 CRISPR adaptation complex RD Fagerlund, ME Wilkinson, O Klykov, A Barendregt, FG Pearce, ... Proceedings of the National Academy of Sciences 114 (26), E5122-E5128, 2017 | 115 | 2017 |
Postcatalytic spliceosome structure reveals mechanism of 3′–splice site selection ME Wilkinson, SM Fica, WP Galej, CM Norman, AJ Newman, K Nagai Science 358 (6368), 1283-1288, 2017 | 108 | 2017 |
Prokaryotic innate immunity through pattern recognition of conserved viral proteins LA Gao, ME Wilkinson, J Strecker, KS Makarova, RK Macrae, EV Koonin, ... Science 377 (6607), eabm4096, 2022 | 97 | 2022 |
A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation SM Fica, C Oubridge, ME Wilkinson, AJ Newman, K Nagai Science 363 (6428), 710-714, 2019 | 97 | 2019 |
RNA-activated protein cleavage with a CRISPR-associated endopeptidase J Strecker, FE Demircioglu, D Li, G Faure, ME Wilkinson, JS Gootenberg, ... Science 378 (6622), 874-881, 2022 | 39 | 2022 |
Structural basis for conformational equilibrium of the catalytic spliceosome ME Wilkinson, SM Fica, WP Galej, K Nagai Molecular Cell 81 (7), 1439-1452. e9, 2021 | 34 | 2021 |
Cryo-EM studies of Pre-mRNA splicing: from sample preparation to model visualization ME Wilkinson, PC Lin, C Plaschka, K Nagai Annual review of biophysics 47, 175-199, 2018 | 29 | 2018 |
Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription ME Wilkinson, CJ Frangieh, RK Macrae, F Zhang Science 380 (6642), 301-308, 2023 | 24 | 2023 |
Methods for merging data sets in electron cryo-microscopy ME Wilkinson, A Kumar, A Casañal Acta Crystallographica Section D: Structural Biology 75 (9), 782-791, 2019 | 23 | 2019 |
Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA S Hirano, K Kappel, H Altae-Tran, G Faure, ME Wilkinson, S Kannan, ... Nature 610 (7932), 575-581, 2022 | 15 | 2022 |
Data-driven regularisation lowers the size barrier of cryo-EM structure determination D Kimanius, K Jamali, ME Wilkinson, S Lövestam, V Velazhahan, ... bioRxiv, 2023.10. 23.563586, 2023 | 12 | 2023 |
Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR–Cas system ME Wilkinson, Y Nakatani, RHJ Staals, SN Kieper, HK Opel-Reading, ... Biochemical Journal 473 (8), 1063-1072, 2016 | 12 | 2016 |
Human paraneoplastic antigen Ma2 (PNMA2) forms icosahedral capsids that can be engineered for mRNA delivery V Madigan, Y Zhang, R Raghavan, ME Wilkinson, G Faure, E Puccio, ... Proceedings of the National Academy of Sciences 121 (11), e2307812120, 2024 | 2 | 2024 |
Similar mechanisms of retron-mediated anti-phage defense for different families of tailed phages FM García-Rodríguez, F Martínez-Abarca, ME Wilkinson, N Toro bioRxiv, 2024.02. 09.579579, 2024 | | 2024 |
Similar mechanisms of retron-mediated anti-phage defense for different families of tailed phages N Toro, FM Garcia-Rodriguez, ME Wilkinson | | 2024 |
Control of 3′ splice site selection by the yeast splicing factor Fyv6 K Senn, K Lipinski, NJ Zeps, AF Griffin, ME Wilkinson, A Hoskins bioRxiv, 2024.05. 04.592262, 2024 | | 2024 |