| BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats S Saber, ME Youssef, H Sharaf, NA Amin, R El-Shedody, FH Aboutouk, ... Life Sciences 270, 119123, 2021 | 48 | 2021 |
| Interference with the AMPKα/mTOR/NLRP3 signaling and the IL-23/IL-17 axis effectively protects against the dextran sulfate sodium intoxication in rats: a new paradigm in … ME Youssef, EE Abd El-Fattah, AM Abdelhamid, H Eissa, E El-Ahwany, ... Frontiers in pharmacology 12, 719984, 2021 | 38* | 2021 |
| Cardioprotective role of GTS-21 by attenuating the TLR4/NF-κB pathway in streptozotocin-induced diabetic cardiomyopathy in rats ME Youssef, HM Abdelrazek, YM Moustafa Naunyn-Schmiedeberg's Archives of Pharmacology 394, 11-31, 2021 | 34 | 2021 |
| Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application AM Abdelhamid, S Saber, ME Youssef, AGA Gaafar, H Eissa, ... Biomedicine & Pharmacotherapy 145, 112455, 2022 | 30 | 2022 |
| Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated … AM Abdelhamid, ME Youssef, EE Abd El-Fattah, NA Gobba, AGA Gaafar, ... Life Sciences 286, 120070, 2021 | 28 | 2021 |
| Unlocking the full potential of SGLT2 inhibitors: expanding applications beyond glycemic control ME Youssef, G Yahya, MS Popoviciu, S Cavalu, MA Abd-Eldayem, ... International Journal of Molecular Sciences 24 (7), 6039, 2023 | 25 | 2023 |
| Electrocardiographic and histopathological characterizations of diabetic cardiomyopathy in rats ME Youssef, MF El-Azab, MA Abdel-Dayem, G Yahya, IS Alanazi, S Saber Environmental Science and Pollution Research, 1-10, 2022 | 24 | 2022 |
| AKT-AMPKα-mTOR-dependent HIF-1α activation is a new therapeutic target for cancer treatment: a novel approach to repositioning the antidiabetic drug sitagliptin for the … EE Abd El-Fattah, S Saber, ME Youssef, H Eissa, E El-Ahwany, NA Amin, ... Frontiers in Pharmacology 12, 720173, 2022 | 21 | 2022 |
| The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced … S Saber, G Yahya, NA Gobba, H Sharaf, R Alshaman, A Alattar, NA Amin, ... Journal of Inflammation Research 14, 3443-3463, 2021 | 21 | 2021 |
| Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis M Nasr, S Cavalu, S Saber, ME Youssef, AM Abdelhamid, HI Elagamy, ... Biomedicine & Pharmacotherapy 153, 113409, 2022 | 18 | 2022 |
| Carbocisteine as a modulator of Nrf2/HO-1 and NFκB interplay in rats: new inspiration for the revival of an old drug for treating ulcerative colitis AM Abdelhamid, ME Youssef, S Cavalu, G Mostafa-Hedeab, A Youssef, ... Frontiers in pharmacology 13, 887233, 2022 | 17 | 2022 |
| Role of ganetespib, an HSP90 inhibitor, in cancer therapy: from molecular mechanisms to clinical practice ME Youssef, S Cavalu, AM Hasan, G Yahya, MA Abd-Eldayem, S Saber International Journal of Molecular Sciences 24 (5), 5014, 2023 | 15 | 2023 |
| Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling S Saber, EE Abd El-Fattah, AM Abdelhamid, AAE Mourad, ... Biomedicine & Pharmacotherapy 158, 114196, 2023 | 15 | 2023 |
| Ambroxol, a mucolytic agent, boosts HO‐1, suppresses NF‐κB, and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating … S Cavalu, H Sharaf, S Saber, ME Youssef, AM Abdelhamid, AAE Mourad, ... The FASEB Journal 36 (9), e22496, 2022 | 15 | 2022 |
| Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need MH Zohny, S Cavalu, ME Youssef, MMY Kaddah, AAE Mourad, ... Biomedicine & Pharmacotherapy 148, 112723, 2022 | 15 | 2022 |
| α7-nAChRs-mediated therapeutic angiogenesis accounts for the advantageous effect of low nicotine doses against myocardial infarction in rats MFEA Mahmoud E Youssef, Mahmoud M El-Mas, Heba M Abdelrazek European Journal of Pharmacology 898, 2021 | 15* | 2021 |
| Pimitespib, an HSP90 inhibitor, augments nifuroxazide-induced disruption in the IL-6/STAT3/HIF-1α autocrine loop in rats with bleomycin-challenged lungs: Evolutionary … DH El-Kashef, ME Youssef, M Nasr, M Alrouji, S Alhajlah, O AlOmeir, ... Biomedicine & Pharmacotherapy 153, 113487, 2022 | 12 | 2022 |
| A novel therapeutic combination of dapagliflozin, Lactobacillus and crocin attenuates diabetic cardiomyopathy in rats: Role of oxidative stress, gut microbiota, and PPARγ … EM Khalaf, HM Hassan, AM El-Baz, A Shata, AE Khodir, ME Yousef, ... European Journal of Pharmacology 931, 175172, 2022 | 10 | 2022 |
| Ameliorative effect of dabigatran on CFA-induced rheumatoid arthritis via modulating kallikrein-kinin system in rats ME Youssef, MA Abdel-Reheim, MA Morsy, M El-Daly, GMK Atwa, ... International Journal of Molecular Sciences 23 (18), 10297, 2022 | 7 | 2022 |
| Molecular mechanisms of α7-nAchR-mediated anti-inflammatory effects ME Youssef, Y Moustafa, H Abdelrazek Indian Journal of Physiology and Pharmacology 64 (3), 158-173, 2021 | 7 | 2021 |
