| T cell receptor signaling precedes immunological synapse formation KH Lee, AD Holdorf, ML Dustin, AC Chan, PM Allen, AS Shaw Science 295 (5559), 1539-1542, 2002 | 925 | 2002 |
| A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts ML Dustin, MW Olszowy, AD Holdorf, J Li, S Bromley, N Desai, P Widder, ... Cell 94 (5), 667-677, 1998 | 882 | 1998 |
| A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl PJ Plant, JP Fawcett, DCC Lin, AD Holdorf, K Binns, S Kulkarni, T Pawson Nature cell biology 5 (4), 301-308, 2003 | 465 | 2003 |
| Regulation of Lck activity by CD4 and CD28 in the immunological synapse AD Holdorf, KH Lee, WR Burack, PM Allen, AS Shaw Nature immunology 3 (3), 259-264, 2002 | 296 | 2002 |
| Proline residues in CD28 and the Src homology (SH) 3 domain of Lck are required for T cell costimulation AD Holdorf, JM Green, SD Levin, MF Denny, DB Straus, V Link, ... The Journal of experimental medicine 190 (3), 375-384, 1999 | 235 | 1999 |
| Cutting edge: quantitative imaging of raft accumulation in the immunological synapse WR Burack, KH Lee, AD Holdorf, ML Dustin, AS Shaw The Journal of Immunology 169 (6), 2837-2841, 2002 | 183 | 2002 |
| WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data AD Holdorf, DP Higgins, AC Hart, PR Boag, GJ Pazour, AJM Walhout, ... Genetics 214 (2), 279-294, 2020 | 133 | 2020 |
| Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans E Watson, V Olin-Sandoval, MJ Hoy, CH Li, T Louisse, V Yao, A Mori, ... Elife 5, e17670, 2016 | 115 | 2016 |
| C. elegans and its bacterial diet as a model for systems-level understanding of host–microbiota interactions J Zhang, AD Holdorf, AJM Walhout Current opinion in biotechnology 46, 74-80, 2017 | 96 | 2017 |
| CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1 KD Carey, TJ Dillon, JM Schmitt, AM Baird, AD Holdorf, DB Straus, ... Molecular and cellular biology 20 (22), 8409-8419, 2000 | 93 | 2000 |
| AVX-470: a novel oral anti-TNF antibody with therapeutic potential in inflammatory bowel disease KC Bhol, DE Tracey, BR Lemos, GD Lyng, EC Erlich, DM Keane, ... Inflammatory bowel diseases 19 (11), 2273-2281, 2013 | 67 | 2013 |
| A gene‐centered C. elegans protein–DNA interaction network provides a framework for functional predictions JI Fuxman Bass, C Pons, L Kozlowski, JS Reece‐Hoyes, S Shrestha, ... Molecular systems biology 12 (10), 884, 2016 | 65 | 2016 |
| A delicate balance between bacterial iron and reactive oxygen species supports optimal C. elegans development J Zhang, X Li, M Olmedo, AD Holdorf, Y Shang, M Artal-Sanz, LS Yilmaz, ... Cell host & microbe 26 (3), 400-411. e3, 2019 | 47 | 2019 |
| A persistence detector for metabolic network rewiring in an animal JT Bulcha, GE Giese, MZ Ali, YU Lee, MD Walker, AD Holdorf, LS Yilmaz, ... Cell reports 26 (2), 460-468. e4, 2019 | 44 | 2019 |
| Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire E Roy, D Togbe, AD Holdorf, D Trubetskoy, S Nabti, G Küblbeck, ... Proceedings of the National Academy of Sciences 107 (35), 15529-15534, 2010 | 35 | 2010 |
| CD28 and T cell co-stimulation. AD Holdorf, O Kanagawa, AS Shaw Reviews in immunogenetics 2 (2), 175-184, 2000 | 35 | 2000 |
| Fine tuning of the threshold of T cell selection by the Nck adapters E Roy, D Togbe, A Holdorf, D Trubetskoy, S Nabti, G Küblbeck, S Schmitt, ... The journal of immunology 185 (12), 7518-7526, 2010 | 23 | 2010 |
| WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization MD Walker, GE Giese, AD Holdorf, S Bhattacharya, C Diot, ... Genetics 219 (1), iyab089, 2021 | 20 | 2021 |
| Transcriptional regulation of metabolic flux: A Caenorhabditis elegans perspective GE Giese, S Nanda, AD Holdorf, AJM Walhout Current Opinion in Systems Biology 15, 12-18, 2019 | 9 | 2019 |
| Many transcription factors contribute to C. elegans growth and fat storage A Mori, AD Holdorf, AJM Walhout Genes to Cells 22 (9), 770-784, 2017 | 9 | 2017 |
Andrey ShawSenior Staff Scientist, GenentechVerified email at gene.com
