Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, ... Nature 574 (7779), 553-558, 2019 | 224 | 2019 |
Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex Y Urano, H Watanabe, SR Murphy, Y Shibuya, Y Geng, AA Peden, ... Proceedings of the National Academy of Sciences 105 (43), 16513-16518, 2008 | 141 | 2008 |
Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1–42 clearance Y Shibuya, CCY Chang, LH Huang, EY Bryleva, TY Chang Journal of Neuroscience 34 (43), 14484-14501, 2014 | 101 | 2014 |
ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease Y Shibuya, CCY Chang, TY Chang Future medicinal chemistry 7 (18), 2451-2467, 2015 | 93 | 2015 |
Acyl-coenzyme A: cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at … Y Shibuya, Z Niu, EY Bryleva, BT Harris, SR Murphy, A Kheirollah, ... Neurobiology of aging 36 (7), 2248-2259, 2015 | 76 | 2015 |
Treatment of a genetic brain disease by CNS-wide microglia replacement Y Shibuya, KK Kumar, MMD Mader, Y Yoo, LA Ayala, M Zhou, MA Mohr, ... Science translational medicine 14 (636), eabl9945, 2022 | 49 | 2022 |
Direct reprogramming of human neurons identifies MARCKSL1 as a pathogenic mediator of valproic acid-induced teratogenicity S Chanda, CE Ang, QY Lee, M Ghebrial, D Haag, Y Shibuya, M Wernig, ... Cell stem cell 25 (1), 103-119. e6, 2019 | 48 | 2019 |
Risk factors for proximal junctional fracture following fusion surgery for osteoporotic vertebral collapse with delayed neurological deficits: a retrospective cohort study of … K Tamai, H Terai, A Suzuki, H Nakamura, K Watanabe, K Katsumi, ... Spine surgery and related research 3 (2), 171-177, 2019 | 21 | 2019 |
A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer’s disease Y Yoo, G Neumayer, Y Shibuya, MMD Mader, M Wernig Cell stem cell 30 (8), 1043-1053. e6, 2023 | 18 | 2023 |
Effect of bisphosphonates or teriparatide on mechanical complications after posterior instrumented fusion for osteoporotic vertebral fracture: a multi-center retrospective study A Kawabata, T Yoshii, T Hirai, S Ushio, T Kaito, T Yamashita, H Fujiwara, ... BMC Musculoskeletal Disorders 21, 1-10, 2020 | 18 | 2020 |
Five-year longitudinal study of frailty prevalence and course assessed using the Kihon Checklist among community-dwelling older adults in Japan M Ohashi, T Yoda, N Imai, T Fujii, K Watanabe, H Tashi, Y Shibuya, ... Scientific reports 11 (1), 12399, 2021 | 13 | 2021 |
Short-versus long-segment posterior spinal fusion with vertebroplasty for osteoporotic vertebral collapse with neurological impairment in thoracolumbar spine: a multicenter study Y Ishikawa, K Watanabe, K Katsumi, M Ohashi, Y Shibuya, T Izumi, ... BMC Musculoskeletal Disorders 21, 1-8, 2020 | 10 | 2020 |
Impact of the flexibility of the spinal deformity on low back pain and disc degeneration in adult patients nonoperatively treated for adolescent idiopathic scoliosis with … M Ohashi, K Watanabe, T Hirano, K Hasegawa, K Katsumi, H Tashi, ... Spine Deformity 10 (1), 133-140, 2022 | 7 | 2022 |
Preoperative prediction for regaining ambulatory ability in paretic non-ambulatory patients with metastatic spinal cord compression M Ohashi, T Hirano, K Watanabe, K Katsumi, H Shoji, A Sano, H Tashi, ... Spinal Cord 55 (5), 447-453, 2017 | 7 | 2017 |
Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons CC Chou, R Vest, MA Prado, J Wilson-Grady, JA Paulo, Y Shibuya, ... bioRxiv, 2023.03. 27.534444, 2023 | 6 | 2023 |
Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease TY Chang, CCY Chang, Y Shibuya, E Bryleva, S Murphy, MA Rogers US Patent 9,149,492, 2015 | 5 | 2015 |
Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases TY Chang, CCY Chang, Y Shibuya, Z Niu US Patent 9,388,413, 2016 | 4 | 2016 |
Evaluating flexibility and predicting curve correction using fulcrum-bending radiographs in Lenke type 2 adolescent idiopathic scoliosis K Watanabe, M Ohashi, H Sekimoto, H Tashi, Y Shibuya, T Makino, ... Journal of Orthopaedic Science 28 (3), 529-535, 2023 | 3 | 2023 |
Effect of adjuvant therapy with teriparatide in patients with thoracolumbar osteoporotic vertebral fractures who underwent vertebroplasty with posterior spinal fusion Y Shibuya, K Katsumi, M Ohashi, H Tashi, T Makino, A Yamazaki, ... Scientific Reports 12 (1), 8854, 2022 | 3 | 2022 |
Association of success of brace treatment and various aspects of in-brace correction in patients with adolescent idiopathic scoliosis M Sato, M Ohashi, H Tashi, T Makino, Y Shibuya, T Hirano, K Watanabe Journal of Orthopaedic Science 28 (6), 1221-1226, 2023 | 2 | 2023 |