Homocyst (e) ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase GR Upchurch, GN Welch, AJ Fabian, JE Freedman, JL Johnson, ... Journal of Biological Chemistry 272 (27), 17012-17017, 1997 | 933 | 1997 |
Circulating platelets as mediators of immunity, inflammation, and thrombosis M Koupenova, L Clancy, HA Corkrey, JE Freedman Circulation research 122 (2), 337-351, 2018 | 770 | 2018 |
Circulating extracellular vesicles in human disease R Shah, T Patel, JE Freedman New England Journal of Medicine 379 (10), 958-966, 2018 | 652 | 2018 |
Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release JE Freedman, C Parker Iii, L Li, JA Perlman, B Frei, V Ivanov, LR Deak, ... Circulation 103 (23), 2792-2798, 2001 | 632 | 2001 |
The burden attributable to mental and substance use disorders as risk factors for suicide: findings from the Global Burden of Disease Study 2010 AJ Ferrari, RE Norman, G Freedman, AJ Baxter, JE Pirkis, MG Harris, ... PloS one 9 (4), e91936, 2014 | 546 | 2014 |
Nitric oxide released from activated platelets inhibits platelet recruitment. JE Freedman, J Loscalzo, MR Barnard, C Alpert, JF Keaney, ... The Journal of clinical investigation 100 (2), 350-356, 1997 | 494 | 1997 |
Thrombosis and platelets: an update M Koupenova, BE Kehrel, HA Corkrey, JE Freedman European heart journal 38 (11), 785-791, 2017 | 465 | 2017 |
α-Tocopherol inhibits aggregation of human platelets by a protein kinase C–dependent mechanism JE Freedman, JH Farhat, J Loscalzo, JF Keaney Circulation 94 (10), 2434-2440, 1996 | 416 | 1996 |
Oxidative stress and platelets JE Freedman Arteriosclerosis, thrombosis, and vascular biology 28 (3), s11-s16, 2008 | 404 | 2008 |
Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets UR Schwarz, J Geiger, U Walter, M Eigenthaler Thrombosis and haemostasis 82 (09), 1145-1152, 1999 | 380 | 1999 |
Platelet–monocyte aggregates: bridging thrombosis and inflammation JE Freedman, J Loscalzo Circulation 105 (18), 2130-2132, 2002 | 334 | 2002 |
Aspirin resistance and atherothrombotic disease PJ Mason, AK Jacobs, JE Freedman Journal of the American College of Cardiology 46 (6), 986-993, 2005 | 323 | 2005 |
Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene JE Freedman, R Sauter, EM Battinelli, K Ault, C Knowles, PL Huang, ... Circulation research 84 (12), 1416-1421, 1999 | 322 | 1999 |
Inducible Toll‐like receptor and NF‐κB regulatory pathway expression in human adipose tissue OI Vitseva, K Tanriverdi, TT Tchkonia, JL Kirkland, ME McDonnell, ... Obesity 16 (5), 932-937, 2008 | 316 | 2008 |
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase P Blair, S Rex, O Vitseva, L Beaulieu, K Tanriverdi, S Chakrabarti, ... Circulation research 104 (3), 346-354, 2009 | 300 | 2009 |
The role of platelets in mediating a response to human influenza infection M Koupenova, HA Corkrey, O Vitseva, G Manni, CJ Pang, L Clancy, ... Nature communications 10 (1), 1780, 2019 | 267 | 2019 |
Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis M Koupenova, O Vitseva, CR MacKay, LM Beaulieu, EJ Benjamin, E Mick, ... Blood, The Journal of the American Society of Hematology 124 (5), 791-802, 2014 | 266 | 2014 |
Platelets and platelet-like particles mediate intercellular RNA transfer A Risitano, LM Beaulieu, O Vitseva, JE Freedman Blood, The Journal of the American Society of Hematology 119 (26), 6288-6295, 2012 | 237 | 2012 |
Diverse human extracellular RNAs are widely detected in human plasma JE Freedman, M Gerstein, E Mick, J Rozowsky, D Levy, R Kitchen, S Das, ... Nature communications 7 (1), 11106, 2016 | 219 | 2016 |
Impaired platelet production of nitric oxide predicts presence of acute coronary syndromes JE Freedman, B Ting, B Hankin, J Loscalzo, JF Keaney Jr, JA Vita Circulation 98 (15), 1481-1486, 1998 | 217 | 1998 |