The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2 AL Hsu, TT Ching, DS Wang, X Song, VM Rangnekar, CS Chen Journal of Biological Chemistry 275 (15), 11397-11403, 2000 | 909 | 2000 |
Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease Q Guo, W Fu, J Xie, H Luo, SF Sells, JW Geddes, V Bondada, ... Nature medicine 4 (8), 957-962, 1998 | 369 | 1998 |
Suppression of PTEN expression by NF-κB prevents apoptosis KM Vasudevan, S Gurumurthy, VM Rangnekar Molecular and cellular biology 24 (3), 1007-1021, 2004 | 356 | 2004 |
Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and-independent prostate cells SF Sells, DP Wood, SS Joshi-Barve, S Muthukumar, RJ Jacob, SA Crist, ... Cell Growth and Differentiation 5, 457-457, 1994 | 356 | 1994 |
A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms’ tumor suppressor WT1 RW Johnstone, RH See, SF Sells, J Wang, S Muthukkumar, C Englert, ... Molecular and cellular biology 16 (12), 6945-6956, 1996 | 324 | 1996 |
The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis R Burikhanov, Y Zhao, A Goswami, S Qiu, SR Schwarze, VM Rangnekar Cell 138 (2), 377-388, 2009 | 310 | 2009 |
Suppression of growth and transformation and induction of apoptosis by EGR-1. C Liu, VM Rangnekar, E Adamson, D Mercola Cancer gene therapy 5 (1), 3-28, 1998 | 303 | 1998 |
Expression and function of the leucine zipper protein Par-4 in apoptosis SF Sells, SS Han, S Muthukkumar, N Maddiwar, R Johnstone, E Boghaert, ... Molecular and cellular biology, 1997 | 259 | 1997 |
Early growth response-1-dependent apoptosis is mediated by p53 P Nair, S Muthukkumar, SF Sells, SS Han, VP Sukhatme, VM Rangnekar Journal of biological chemistry 272 (32), 20131-20138, 1997 | 250 | 1997 |
Binding and phosphorylation of par-4 by akt is essential for cancer cell survival A Goswami, R Burikhanov, A de Thonel, N Fujita, M Goswami, Y Zhao, ... Molecular cell 20 (1), 33-44, 2005 | 233 | 2005 |
Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression M Chakraborty, SG Qiu, KM Vasudevan, VM Rangnekar Cancer research 61 (19), 7255-7263, 2001 | 231 | 2001 |
Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells N El-Guendy, Y Zhao, S Gurumurthy, R Burikhanov, VM Rangnekar Molecular and cellular biology, 2003 | 210 | 2003 |
Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma J Cook, S Krishnan, S Ananth, SF Sells, Y Shi, MCM Walther, ... Oncogene 18 (5), 1205-1208, 1999 | 184 | 1999 |
Apoptosis by Par-4 in cancer and neurodegenerative diseases N El-Guendy, VM Rangnekar Experimental cell research 283 (1), 51-66, 2003 | 181 | 2003 |
Identification of bone marrow micrometastases in patients with prostate cancer DP Wood Jr, ER Banks, S Humphreys, JW McRoberts, VM Rangnekar Cancer 74 (9), 2533-2540, 1994 | 176 | 1994 |
Phosphorylation of Par-4 by protein kinase A is critical for apoptosis S Gurumurthy, A Goswami, KM Vasudevan, VM Rangnekar Molecular and cellular biology, 2005 | 172 | 2005 |
Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter SK Cheema, SK Mishra, VM Rangnekar, AM Tari, R Kumar, ... Journal of Biological Chemistry 278 (22), 19995-20005, 2003 | 171 | 2003 |
Role of tumor necrosis factor-α and TRAIL in high-dose radiation–induced bystander signaling in lung adenocarcinoma MM Shareef, N Cui, R Burikhanov, S Gupta, S Satishkumar, S Shajahan, ... Cancer research 67 (24), 11811-11820, 2007 | 155 | 2007 |
Regulation of apoptosis in prostate cancer S Gurumurthy, K Murthi Vasudevan, VM Rangnekar Cancer and Metastasis Reviews 20, 225-243, 2001 | 151 | 2001 |
Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis G Page, D Kögel, V Rangnekar, KH Scheidtmann Oncogene 18 (51), 7265-7273, 1999 | 149 | 1999 |