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Tyler Goodwin
Tyler Goodwin
University of North Carolina Chapel Hill
Verified email at precisionbiosciences.com
Title
Cited by
Cited by
Year
Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap
W Song, L Shen, Y Wang, Q Liu, TJ Goodwin, J Li, O Dorosheva, T Liu, ...
Nature communications 9 (1), 2237, 2018
3402018
Quercetin remodels the tumor microenvironment to improve the permeation, retention, and antitumor effects of nanoparticles
K Hu, L Miao, TJ Goodwin, J Li, Q Liu, L Huang
ACS nano 11 (5), 4916-4925, 2017
2312017
Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy
J Zhou, M Liu, H Sun, Y Feng, L Xu, AWH Chan, JH Tong, J Wong, ...
Gut 67 (5), 931-944, 2018
1732018
Facile fabrication of tumor redox‐sensitive nanoassemblies of small‐molecule oleate prodrug as potent chemotherapeutic nanomedicine
C Luo, J Sun, B Sun, D Liu, L Miao, TJ Goodwin, L Huang, Z He
Small 12 (46), 6353-6362, 2016
1502016
Transient and local expression of chemokine and immune checkpoint traps to treat pancreatic cancer
L Miao, J Li, Q Liu, R Feng, M Das, CM Lin, TJ Goodwin, O Dorosheva, ...
ACS nano 11 (9), 8690-8706, 2017
1252017
Local blockade of interleukin 10 and CXC motif chemokine ligand 12 with nano-delivery promotes antitumor response in murine cancers
L Shen, J Li, Q Liu, W Song, X Zhang, K Tiruthani, H Hu, M Das, ...
ACS nano 12 (10), 9830-9841, 2018
1112018
Local and transient gene expression primes the liver to resist cancer metastasis
T Goodwin, Y Zhou, S Musetti, R Liu, L Huang
Science Translational Medicine 8 (364), 364ra153, 2016
802016
Nanoparticle delivery of RIG-I agonist enables effective and safe adjuvant therapy in pancreatic cancer
M Das, L Shen, Q Liu, TJ Goodwin, L Huang
Molecular Therapy 27 (3), 507-517, 2019
772019
Investigation of phosphorylated adjuvants co-encapsulated with a model cancer peptide antigen for the treatment of colorectal cancer and liver metastasis
TJ Goodwin, L Huang
Vaccine 35 (19), 2550-2557, 2017
702017
Liver specific gene immunotherapies resolve immune suppressive ectopic lymphoid structures of liver metastases and prolong survival
TJ Goodwin, L Shen, M Hu, J Li, R Feng, O Dorosheva, R Liu, L Huang
Biomaterials 141, 260-271, 2017
522017
Nonviral vectors: we have come a long way
T Goodwin, L Huang
Advances in genetics 88, 1-12, 2014
452014
A circle RNA regulatory axis promotes lung squamous metastasis via CDR1-mediated regulation of Golgi trafficking
EB Harrison, A Porrello, BM Bowman, AR Belanger, G Yacovone, ...
Cancer research 80 (22), 4972-4985, 2020
262020
Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo
CL Gorsuch, P Nemec, M Yu, S Xu, D Han, J Smith, J Lape, N van Buuren, ...
Molecular Therapy 30 (9), 2909-2922, 2022
172022
Glycoconjugated site-selective DNA-methylating agent targeting glucose transporters on glioma cells
MK Buchanan, CN Needham, NE Neill, MC White, CB Kelly, ...
Biochemistry 56 (2), 421-440, 2017
142017
On the article" Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles"[J. Control. Release 224 (2016) 229-238]: Letter to the …
TJ Goodwin, L Huang
Journal of controlled release: official journal of the Controlled Release …, 2016
132016
Nonviral Vectors for Gene Therapy: Lipid-and Polymer-based Gene Transfer
L Huang, D Liu, E Wagner
Academic Press, 2014
82014
HDAC8 inhibition modulates liver tumor microenvironment: rationale for combined epigenetic and immunotherapy
AS Cheng, Y Feng, J Zhou, W Yang, H Sun, Z Chen, T Goodwin, R Liu, ...
The Journal of Immunology 198 (1_Supplement), 76.26-76.26, 2017
62017
A Gene Editing Approach to Eliminate Hepatitis B Virus Using ARCUS Meganucleases
C Gorsuch, M Yu, S Xu, J Lape, T Goodwin, N Leatherbury, J Smith, ...
MOLECULAR THERAPY 28 (4), 457-458, 2020
22020
Methods and Compositions for Reducing Metastases
L Huang, T Goodwin, R Liu, L Miao
US Patent App. 15/763,065, 2019
12019
Methods and compositions for reducing metastases
L Huang, T GOODWIN, R Liu, L Miao
12017
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