A prevalent peptide-binding domain guides ribosomal natural product biosynthesis BJ Burkhart, GA Hudson, KL Dunbar, DA Mitchell Nature chemical biology 11 (8), 564-570, 2015 | 341 | 2015 |
RiPP antibiotics: biosynthesis and engineering potential GA Hudson, DA Mitchell Current opinion in microbiology 45, 61-69, 2018 | 192 | 2018 |
In vitro biosynthesis of the core scaffold of the thiopeptide thiomuracin GA Hudson, Z Zhang, JI Tietz, DA Mitchell, WA Van Der Donk Journal of the American Chemical Society 137 (51), 16012-16015, 2015 | 170 | 2015 |
Bioinformatic Mapping of Radical S-Adenosylmethionine-Dependent Ribosomally Synthesized and Post-Translationally Modified Peptides Identifies New Cα, Cβ … GA Hudson, BJ Burkhart, AJ DiCaprio, CJ Schwalen, B Kille, ... Journal of the American Chemical Society 141 (20), 8228-8238, 2019 | 144 | 2019 |
Bioinformatic expansion and discovery of thiopeptide antibiotics CJ Schwalen, GA Hudson, B Kille, DA Mitchell Journal of the American Chemical Society 140 (30), 9494-9501, 2018 | 127 | 2018 |
Chimeric leader peptides for the generation of non-natural hybrid RiPP products BJ Burkhart, N Kakkar, GA Hudson, WA Van Der Donk, DA Mitchell ACS Central Science 3 (6), 629-638, 2017 | 117 | 2017 |
Thermodynamic contribution and nearest-neighbor parameters of pseudouridine-adenosine base pairs in oligoribonucleotides GA Hudson, RJ Bloomingdale, BM Znosko Rna 19 (11), 1474-1482, 2013 | 104 | 2013 |
Radical S-Adenosylmethionine Enzymes Involved in RiPP Biosynthesis N Mahanta, GA Hudson, DA Mitchell Biochemistry 56 (40), 5229-5244, 2017 | 82 | 2017 |
Biosynthetic timing and substrate specificity for the thiopeptide thiomuracin Z Zhang, GA Hudson, N Mahanta, JI Tietz, WA Van der Donk, DA Mitchell Journal of the American Chemical Society 138 (48), 15511-15514, 2016 | 78 | 2016 |
Structural insights into enzymatic [4+ 2] aza-cycloaddition in thiopeptide antibiotic biosynthesis DP Cogan, GA Hudson, Z Zhang, TV Pogorelov, WA Van Der Donk, ... Proceedings of the National Academy of Sciences 114 (49), 12928-12933, 2017 | 76 | 2017 |
Enzymatic reconstitution and biosynthetic investigation of the lasso peptide fusilassin AJ DiCaprio, A Firouzbakht, GA Hudson, DA Mitchell Journal of the American Chemical Society 141 (1), 290-297, 2018 | 74 | 2018 |
Targeting reactive carbonyls for identifying natural products and their biosynthetic origins T Maxson, JI Tietz, GA Hudson, XR Guo, HC Tai, DA Mitchell Journal of the American Chemical Society 138 (46), 15157-15166, 2016 | 48 | 2016 |
Reconstitution and Substrate Specificity of the Radical S-Adenosyl-methionine Thiazole C-Methyltransferase in Thiomuracin Biosynthesis N Mahanta, Z Zhang, GA Hudson, WA Van Der Donk, DA Mitchell Journal of the American Chemical Society 139 (12), 4310-4313, 2017 | 47 | 2017 |
RNA CoSSMos: characterization of secondary structure motifs—a searchable database of secondary structure motifs in RNA three-dimensional structures PL Vanegas, GA Hudson, AR Davis, SC Kelly, CC Kirkpatrick, BM Znosko Nucleic acids research 40 (D1), D439-D444, 2012 | 44 | 2012 |
In vitro biosynthetic studies of bottromycin expand the enzymatic capabilities of the YcaO superfamily CJ Schwalen, GA Hudson, S Kosol, N Mahanta, GL Challis, DA Mitchell Journal of the American Chemical Society 139 (50), 18154-18157, 2017 | 33 | 2017 |
Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase Z Zhang, N Mahanta, GA Hudson, DA Mitchell, WA Van Der Donk Journal of the American Chemical Society 139 (51), 18623-18631, 2017 | 30 | 2017 |
Effect of intercalator substituent and nucleotide sequence on the stability of DNA-and RNA-naphthalimide complexes CA Johnson, GA Hudson, LKE Hardebeck, EA Jolley, Y Ren, M Lewis, ... Bioorganic & Medicinal Chemistry 23 (13), 3586-3591, 2015 | 25 | 2015 |
Structure prediction and synthesis of pyridine-based macrocyclic peptide natural products GA Hudson, AR Hooper, AJ DiCaprio, D Sarlah, DA Mitchell Organic letters 23 (2), 253-256, 2020 | 23 | 2020 |
Reactivity-based screening for citrulline-containing natural products reveals a family of bacterial peptidyl arginine deiminases LA Harris, PMB Saint-Vincent, X Guo, GA Hudson, AJ DiCaprio, L Zhu, ... ACS chemical biology 15 (12), 3167-3175, 2020 | 21 | 2020 |
Accessing diverse pyridine-based macrocyclic peptides by a two-site recognition pathway DT Nguyen, TT Le, AJ Rice, GA Hudson, WA Van Der Donk, DA Mitchell Journal of the American Chemical Society 144 (25), 11263-11269, 2022 | 10 | 2022 |