Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment MF Lensink, G Brysbaert, T Mauri, N Nadzirin, S Velankar, RAG Chaleil, ... Proteins: Structure, Function, and Bioinformatics 89 (12), 1800-1823, 2021 | 81 | 2021 |
Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants MS Cline, G Babbi, S Bonache, Y Cao, R Casadio, X de la Cruz, O Díez, ... Human Mutation 40 (9), 1546-1556, 2019 | 19 | 2019 |
Impact of AlphaFold on structure prediction of protein complexes: the CASP15‐CAPRI experiment MF Lensink, G Brysbaert, N Raouraoua, PA Bates, M Giulini, RV Honorato, ... Proteins: Structure, Function, and Bioinformatics 91 (12), 1658-1683, 2023 | 16 | 2023 |
Predicting protein conformational changes for unbound and homology docking: learning from intrinsic and induced flexibility H Chen, Y Sun, Y Shen Proteins: Structure, Function, and Bioinformatics 85 (3), 544-556, 2017 | 15 | 2017 |
Assessing the performance of in silico methods for predicting the pathogenicity of variants in the gene CHEK2, among Hispanic females with breast cancer A Voskanian, P Katsonis, O Lichtarge, V Pejaver, P Radivojac, ... Human mutation 40 (9), 1612-1622, 2019 | 12 | 2019 |
Predicting pathogenicity of missense variants with weakly supervised regression Y Cao, Y Sun, M Karimi, H Chen, O Moronfoye, Y Shen Human mutation 40 (9), 1579-1592, 2019 | 10 | 2019 |
The ENCODE Imputation Challenge: a critical assessment of methods for cross-cell type imputation of epigenomic profiles J Schreiber, C Boix, J wook Lee, H Li, Y Guan, CC Chang, JC Chang, ... Genome biology 24 (1), 79, 2023 | 8 | 2023 |
Structure-informed protein language models are robust predictors for variant effects Y Sun, Y Shen Research Square, 2023 | 4 | 2023 |
Critical assessment of variant prioritization methods for rare disease diagnosis within the Rare Genomes Project SL Stenton, MC O’Leary, G Lemire, GE VanNoy, S DiTroia, VS Ganesh, ... Human Genomics 18 (1), 44, 2024 | 3 | 2024 |
Physics-driven structural docking and protein language models accelerate antibody screening and design for broad-spectrum antiviral therapy HF Mubarak, W Tan, AD Hoffmann, J Wei, L El-Shennawy, JR Squires, ... bioRxiv, 2024.03. 01.582176, 2024 | | 2024 |
Variant effect prediction using structure-informed protein language models Y Sun, Y Shen Biophysical Journal 122 (3), 473a, 2023 | | 2023 |
Does Inter-Protein Contact Prediction Benefit from Multi-Modal Data and Auxiliary Tasks? A Talukder, R Yin, Y Sun, Y Shen, Y You bioRxiv, 2022.11. 29.518454, 2022 | | 2022 |