High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. KJ Spring, ZZ Zhao, R Karamatic, MD Walsh, VL Whitehall, T Pike, ... Gastroenterology 131 (5), 1400, 2006 | 655 | 2006 |
Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development K Loh, JA Chia, S Greco, SJ Cozzi, RL Buttenshaw, CE Bond, LA Simms, ... Genes, Chromosomes and Cancer 47 (6), 449-460, 2008 | 108 | 2008 |
Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface J Claus, G Patel, F Autore, A Colomba, G Weitsman, TN Soliman, ... eLife 7, e32271, 2018 | 61 | 2018 |
MAPK pathway activation delays G2/M progression by destabilizing Cdc25B P Astuti, T Pike, C Widberg, E Payne, A Harding, J Hancock, B Gabrielli Journal of Biological Chemistry 284 (49), 33781-33788, 2009 | 48 | 2009 |
Equivocal, explicit and emergent actions of PKC isoforms in cancer PJ Parker, SJ Brown, V Calleja, P Chakravarty, M Cobbaut, M Linch, ... Nature Reviews Cancer 21 (1), 51-63, 2021 | 44 | 2021 |
Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma N Tamura, N Shaikh, D Muliaditan, TN Soliman, JR McGuinness, ... Cancer Research 80 (22), 4946-4959, 2020 | 37 | 2020 |
PKCɛ switches Aurora B specificity to exit the abscission checkpoint T Pike, N Brownlow, S Kjaer, J Carlton, PJ Parker Nature Communications 7 (1), 13853, 2016 | 35 | 2016 |
Mitotic catenation is monitored and resolved by a PKCε-regulated pathway N Brownlow, T Pike, D Zicha, L Collinson, PJ Parker Nature communications 5 (1), 5685, 2014 | 31 | 2014 |
A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest K Deiss, N Lockwood, M Howell, HA Segeren, RE Saunders, ... Nucleic Acids Research, 2018 | 26 | 2018 |
PKCϵ controls mitotic progression by regulating centrosome migration and mitotic spindle assembly S Martini, T Soliman, G Gobbi, P Mirandola, C Carubbi, E Masselli, ... Molecular Cancer Research 16 (1), 3-15, 2018 | 23 | 2018 |
Detection and tracking of cell divisions in phase contrast video microscopy S Hadjidemetriou, B Gabrielli, T Pike, F Stevens, K Mele, P Vallotton Proceeding of the Third MICCAI Worshop on Microscopic Image Analysis with …, 2008 | 17 | 2008 |
The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition JR Kelly, S Martini, N Brownlow, D Joshi, S Federico, S Jamshidi, S Kjaer, ... Nature communications 11 (1), 1396, 2020 | 16 | 2020 |
The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition JR Kelly, S Martini, N Brownlow, D Joshi, S Federico, S Jamshidi, S Kjaer, ... Nature communications 11 (1), 1396, 2020 | 16 | 2020 |
A cancer-associated, genome protective programme engaging PKCε PJ Parker, N Lockwood, K Davis, JR Kelly, TN Soliman, AL Pardo, ... Advances in Biological Regulation 78, 100759, 2020 | 8 | 2020 |
Regulation of the cytokinesis cleavage furrow by PKCε N Brownlow, T Pike, V Crossland, J Claus, P Parker Biochemical Society Transactions 42 (6), 1534-1537, 2014 | 8 | 2014 |
Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention L Watson, TN Soliman, K Davis, J Kelly, N Lockwood, X Yang, S Lynham, ... Biochemical Journal 478 (12), 2247-2263, 2021 | 3 | 2021 |
Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells N Lockwood, S Martini, A Lopez-Pardo, K Deiss, HA Segeren, RK Semple, ... Cancer research 82 (9), 1762-1773, 2022 | 2 | 2022 |
Truncated MEK1 is required for transient activation of MAPK signalling in G2 phase cells T Pike, C Widberg, A Goodall, E Payne, N Giles, J Hancock, B Gabrielli Cellular Signalling 25 (6), 1423-1428, 2013 | 2 | 2013 |
Cell cycle responses to Topoisomerase II inhibition: Molecular mechanisms and clinical implications TN Soliman, D Keifenheim, PJ Parker, DJ Clarke Journal of Cell Biology 222 (12), 2023 | 1 | 2023 |
A cancer-associated, genome protective programme engaging PKC? PJ Parker, N Lockwood, K Davis, JR Kelly, TN Soliman, AL Pardo, ... | 1 | 2020 |