Medicinal chemistry and the molecular operating environment (MOE): application of QSAR and molecular docking to drug discovery S Vilar, G Cozza, S Moro Current topics in medicinal chemistry 8 (18), 1555-1572, 2008 | 976 | 2008 |
Insight into the mechanism of ferroptosis inhibition by ferrostatin-1 G Miotto, M Rossetto, ML Di Paolo, L Orian, R Venerando, A Roveri, ... Redox biology 28, 101328, 2020 | 444 | 2020 |
A comparison of thiol peroxidase mechanisms L Flohé, S Toppo, G Cozza, F Ursini Antioxidants & redox signaling 15 (3), 763-780, 2011 | 284 | 2011 |
The selectivity of inhibitors of protein kinase CK2: an update MA Pagano, J Bain, Z Kazimierczuk, S Sarno, M Ruzzene, G Di Maira, ... Biochemical Journal 415 (3), 353-365, 2008 | 276 | 2008 |
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application G Cozza, P Bonvini, E Zorzi, G Poletto, MA Pagano, S Sarno, ... Journal of medicinal chemistry 49 (8), 2363-2366, 2006 | 187 | 2006 |
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 G Cozza, M Mazzorana, E Papinutto, J Bain, M Elliott, G Di Maira, ... Biochemical Journal 421 (3), 387-395, 2009 | 185 | 2009 |
Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer R Battistutta, G Cozza, F Pierre, E Papinutto, G Lolli, S Sarno, SE O’Brien, ... Biochemistry 50 (39), 8478-8488, 2011 | 176 | 2011 |
Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight G Lolli, G Cozza, M Mazzorana, E Tibaldi, L Cesaro, A Donella-Deana, ... Biochemistry 51 (31), 6097-6107, 2012 | 173 | 2012 |
Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure–activity relationships A Chilin, R Battistutta, A Bortolato, G Cozza, S Zanatta, G Poletto, ... Journal of medicinal chemistry 51 (4), 752-759, 2008 | 165 | 2008 |
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors MA Pagano, G Poletto, G Di Maira, G Cozza, M Ruzzene, S Sarno, J Bain, ... Chembiochem 8 (1), 129-139, 2007 | 138 | 2007 |
Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid … G Cozza, M Rossetto, V Bosello-Travain, M Maiorino, A Roveri, S Toppo, ... Free Radical Biology and Medicine 112, 1-11, 2017 | 128 | 2017 |
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study F Meggio, MA Pagano, S Moro, G Zagotto, M Ruzzene, S Sarno, G Cozza, ... Biochemistry 43 (40), 12931-12936, 2004 | 114 | 2004 |
Kinase CK2 inhibition: an update G Cozza, L A Pinna, S Moro Current medicinal chemistry 20 (5), 671-693, 2013 | 107 | 2013 |
Casein kinases as potential therapeutic targets G Cozza, LA Pinna Expert opinion on therapeutic targets 20 (3), 319-340, 2016 | 96 | 2016 |
Protein kinase CK2 inhibitors: a patent review G Cozza, LA Pinna, S Moro Expert opinion on therapeutic patents 22 (9), 1081-1097, 2012 | 87 | 2012 |
How druggable is protein kinase CK2? G Cozza, A Bortolato, S Moro Medicinal Research Reviews 30 (3), 419-462, 2010 | 78 | 2010 |
Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 A Gianoncelli, G Cozza, A Orzeszko, F Meggio, Z Kazimierczuk, LA Pinna Bioorganic & medicinal chemistry 17 (20), 7281-7289, 2009 | 73 | 2009 |
The development of CK2 inhibitors: From traditional pharmacology to in silico rational drug design G Cozza Pharmaceuticals 10 (1), 26, 2017 | 72 | 2017 |
Identification of novel protein kinase CK1 delta (CK1δ) inhibitors through structure-based virtual screening G Cozza, A Gianoncelli, M Montopoli, L Caparrotta, A Venerando, ... Bioorganic & medicinal chemistry letters 18 (20), 5672-5675, 2008 | 71 | 2008 |
Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma T Purzner, J Purzner, T Buckstaff, G Cozza, S Gholamin, JM Rusert, ... Science signaling 11 (547), eaau5147, 2018 | 70 | 2018 |