Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting X Ma, X Qu, W Zhu, YS Li, S Yuan, H Zhang, J Liu, P Wang, CSE Lai, ... Proceedings of the National Academy of Sciences 113 (8), 2206-2211, 2016 | 809 | 2016 |
High content screening: seeing is believing F Zanella, JB Lorens, W Link Trends in biotechnology 28 (5), 237-245, 2010 | 504 | 2010 |
Mechanotransduction in cardiac hypertrophy and failure RC Lyon, F Zanella, JH Omens, F Sheikh Circulation research 116 (8), 1462-1476, 2015 | 325 | 2015 |
Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells F Zanella, O Renner, B García, S Callejas, A Dopazo, S Peregrina, ... Oncogene 29 (20), 2973-2982, 2010 | 125 | 2010 |
Nonlinear 3D projection printing of concave hydrogel microstructures for long-term multicellular spheroid and embryoid body culture KC Hribar, D Finlay, X Ma, X Qu, MG Ondeck, PH Chung, F Zanella, ... Lab on a Chip 15 (11), 2412-2418, 2015 | 102 | 2015 |
Chemical Genetic Analysis of FOXO Nuclear–Cytoplasmic Shuttling by Using Image‐Based Cell Screening F Zanella, A Rosado, B García, A Carnero, W Link Chembiochem 9 (14), 2229-2237, 2008 | 92 | 2008 |
Functional and mechanistic neurotoxicity profiling using human iPSC-derived neural 3D cultures O Sirenko, F Parham, S Dea, N Sodhi, S Biesmans, S Mora-Castilla, ... Toxicological Sciences 167 (1), 58-76, 2019 | 75 | 2019 |
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids CA Trujillo, JW Adams, PD Negraes, C Carromeu, L Tejwani, A Acab, ... EMBO Molecular Medicine 13 (1), e12523, 2021 | 63 | 2021 |
Understanding FOXO, new views on old transcription factors F Zanella, W Link, A Carnero Current cancer drug targets 10 (2), 135-146, 2010 | 62 | 2010 |
An HTS approach to screen for antagonists of the nuclear export machinery using high content cell-based assays F Zanella, A Rosado, F Blanco, BR Henderson, A Carnero, W Link Assay and drug development technologies 5 (3), 333-342, 2007 | 49 | 2007 |
Using multiplexed regulation of luciferase activity and GFP translocation to screen for FOXO modulators F Zanella, A Rosado, B Garcia, A Carnero, W Link BMC cell biology 10, 1-10, 2009 | 44 | 2009 |
Moving to the Core: Spatiotemporal Analysis of Forkhead Box O (FOXO) and Nuclear Factor‐κB (NF‐κB) Nuclear Translocation F Zanella, NR Dos Santos, W Link Traffic 14 (3), 247-258, 2013 | 32 | 2013 |
Modeling heart disease in a dish: from somatic cells to disease-relevant cardiomyocytes F Zanella, RC Lyon, F Sheikh Trends in cardiovascular medicine 24 (1), 32-44, 2014 | 27 | 2014 |
A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling A Rosado, F Zanella, B Garcia, A Carnero, W Link PLoS One 3 (3), e1823, 2008 | 23 | 2008 |
Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids G Woodruff, N Phillips, C Carromeu, O Guicherit, A White, MC Johnson, ... PLoS One 15 (10), e0240991, 2020 | 18 | 2020 |
Human iPSC-derived 2D and 3D platforms for rapidly assessing developmental, functional, and terminal toxicities in neural cells I Slavin, S Dea, P Arunkumar, N Sodhi, S Montefusco, J Siqueira-Neto, ... International journal of molecular sciences 22 (4), 1908, 2021 | 11 | 2021 |
Patient-specific induced pluripotent stem cell models: generation and characterization of cardiac cells F Zanella, F Sheikh Patient-Specific Induced Pluripotent Stem Cell Models: Generation and …, 2016 | 8 | 2016 |
Adding more content to screening: reactivation of FOXO as a therapeutic strategy F Zanella, A Carnero Clinical and Translational Oncology 11, 651-658, 2009 | 8 | 2009 |
Functional evaluation of neurotoxic compounds using human iPSC–derived neuronal 3D cultures O Sirenko, S Vargas-Hurlston, G Chandy, C Crittenden, R Gordon, ... Journal of Pharmacological and Toxicological Methods 99, 106595, 2019 | 3 | 2019 |
Connexin43 as a gene therapy to circumvent arrhythmogenic cardiomyopathy J Zhang, F Zanella, R Lyon, V Mezzano, J Roberts, P Ursell, C Carromeu, ... The FASEB Journal 35, 2021 | 1 | 2021 |