| Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation: a role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM) EA Goncharova, DA Goncharov, A Eszterhas, DS Hunter, MK Glassberg, ... Journal of Biological Chemistry 277 (34), 30958-30967, 2002 | 517 | 2002 |
| SIRT3–AMP-activated protein kinase activation by nitrite and metformin improves hyperglycemia and normalizes pulmonary hypertension associated with heart failure with preserved … YC Lai, DM Tabima, JJ Dube, KS Hughan, RR Vanderpool, ... Circulation 133 (8), 717-731, 2016 | 240 | 2016 |
| PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells EA Goncharova, AJ Ammit, C Irani, RG Carroll, AJ Eszterhas, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (2 …, 2002 | 238 | 2002 |
| Vitamin D inhibits growth of human airway smooth muscle cells through growth factor‐induced phosphorylation of retinoblastoma protein and checkpoint kinase 1 G Damera, HW Fogle, P Lim, EA Goncharova, H Zhao, A Banerjee, ... British journal of pharmacology 158 (6), 1429-1441, 2009 | 220 | 2009 |
| Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension DA Goncharov, TV Kudryashova, H Ziai, K Ihida-Stansbury, H DeLisser, ... Circulation 129 (8), 864-874, 2014 | 186 | 2014 |
| mTORC 1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts Y Romero, M Bueno, R Ramirez, D Álvarez, JC Sembrat, EA Goncharova, ... Aging cell 15 (6), 1103-1112, 2016 | 156 | 2016 |
| Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration EA Goncharova, CK Billington, C Irani, AV Vorotnikov, VA Tkachuk, ... American journal of respiratory cell and molecular biology 29 (1), 19-27, 2003 | 151 | 2003 |
| mTORC2 is required for proliferation and survival of TSC2-null cells EA Goncharova, DA Goncharov, H Li, W Pimtong, S Lu, I Khavin, ... Molecular and cellular biology 31 (12), 2484-2498, 2011 | 141 | 2011 |
| Translational Advances in the Field of Pulmonary Hypertension.From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics. Targeting Cell … SS Pullamsetti, R Savai, W Seeger, EA Goncharova American journal of respiratory and critical care medicine 195 (4), 425-437, 2017 | 135* | 2017 |
| TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase E Goncharova, D Goncharov, D Noonan, VP Krymskaya The Journal of cell biology 167 (6), 1171-1182, 2004 | 134 | 2004 |
| Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent AS Kazi, S Lotfi, EA Goncharova, O Tliba, Y Amrani, VP Krymskaya, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 286 (3 …, 2004 | 128 | 2004 |
| mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia VP Krymskaya, J Snow, G Cesarone, I Khavin, DA Goncharov, PN Lim, ... The FASEB Journal 25 (6), 1922, 2011 | 118 | 2011 |
| Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration VP Krymskaya, EA Goncharova, AJ Ammit, PN Lim, DA Goncharov, ... The FASEB journal 19 (3), 1-20, 2005 | 117 | 2005 |
| HIPPO–integrin-linked kinase cross-talk controls self-sustaining proliferation and survival in pulmonary hypertension TV Kudryashova, DA Goncharov, A Pena, N Kelly, R Vanderpool, J Baust, ... American journal of respiratory and critical care medicine 194 (7), 866-877, 2016 | 112 | 2016 |
| Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK EA Goncharova, DA Goncharov, ML James, EN Atochina-Vasserman, ... Cell reports 7 (2), 412-423, 2014 | 94 | 2014 |
| HDAC6: a novel histone deacetylase implicated in pulmonary arterial hypertension O Boucherat, S Chabot, R Paulin, I Trinh, A Bourgeois, F Potus, ... Scientific reports 7 (1), 4546, 2017 | 93 | 2017 |
| Modulation of cell migration and invasiveness by tumor suppressor TSC2 in lymphangioleiomyomatosis EA Goncharova, DA Goncharov, PN Lim, D Noonan, VP Krymskaya American journal of respiratory cell and molecular biology 34 (4), 473-480, 2006 | 91 | 2006 |
| PI3K/mTORC1 activation in hamartoma syndromes: therapeutic prospects VP Krymskaya, EA Goncharova Cell Cycle 8 (3), 403-413, 2009 | 90 | 2009 |
| Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migration EA Goncharova, AV Vorotnikov, EO Gracheva, CLA Wang, ... Walter de Gruyter 383 (1), 115-126, 2002 | 88 | 2002 |
| Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion DA Medvetz, D Khabibullin, V Hariharan, PP Ongusaha, EA Goncharova, ... PloS one 7 (11), e47842, 2012 | 86 | 2012 |
Vera KrymskayaProfessor of Medicine, University of PennsylvaniaVerified email at pennmedicine.upenn.edu
