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Lindsey A. Chew
Lindsey A. Chew
Verified email at duke.edu
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Cited by
Cited by
Year
Long-lasting antinociceptive effects of green light in acute and chronic pain in rats
MM Ibrahim, A Patwardhan, KB Gilbraith, A Moutal, X Yang, LA Chew, ...
Pain 158 (2), 347-360, 2017
1032017
CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide
A Moutal, X Yang, W Li, KB Gilbraith, S Luo, S Cai, L François-Moutal, ...
Pain 158 (12), 2301-2319, 2017
752017
(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation …
A Moutal, LA Chew, X Yang, Y Wang, SK Yeon, E Telemi, S Meroueh, ...
Pain 157 (7), 1448-1463, 2016
612016
(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5
A Moutal, L François-Moutal, S Perez-Miller, K Cottier, LA Chew, SK Yeon, ...
Molecular neurobiology 53, 1959-1976, 2016
602016
Dissecting the role of the CRMP2–neurofibromin complex on pain behaviors
A Moutal, Y Wang, X Yang, Y Ji, S Luo, A Dorame, SS Bellampalli, ...
Pain 158 (11), 2203-2221, 2017
572017
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N-and T …
SS Bellampalli, Y Ji, A Moutal, S Cai, EMK Wijeratne, MA Gandini, J Yu, ...
Pain 160 (1), 117-135, 2019
532019
CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain
LA Chew, R Khanna
Neuronal Signaling 2 (1), NS20170220, 2018
432018
Targeting the CaVα–CaVβ interaction yields an antagonist of the N-type CaV2. 2 channel with broad antinociceptive efficacy
R Khanna, J Yu, X Yang, A Moutal, A Chefdeville, V Gokhale, Z Shuja, ...
Pain 160 (7), 1644-1661, 2019
372019
Mining the Nav1. 7 interactome: Opportunities for chronic pain therapeutics
LA Chew, SS Bellampalli, ET Dustrude, R Khanna
Biochemical pharmacology 163, 9-20, 2019
322019
Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential
JY Xie, LA Chew, X Yang, Y Wang, C Qu, Y Wang, LM Federici, SD Fitz, ...
Pain 157 (9), 2124-2140, 2016
322016
Studies on CRMP2 SUMOylation–deficient transgenic mice identify sex-specific Nav1. 7 regulation in the pathogenesis of chronic neuropathic pain
A Moutal, S Cai, J Yu, HJ Stratton, A Chefdeville, K Gomez, D Ran, ...
Pain 161 (11), 2629-2651, 2020
312020
Selective targeting of NaV1. 7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents
S Cai, A Moutal, J Yu, LA Chew, J Isensee, R Chawla, K Gomez, S Luo, ...
Science Translational Medicine 13 (619), eabh1314, 2021
222021
Development and characterization of an injury-free model of functional pain in rats by exposure to red light
R Khanna, A Patwardhan, X Yang, W Li, S Cai, Y Ji, LA Chew, A Dorame, ...
The journal of pain 20 (11), 1293-1306, 2019
202019
Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet
CE Myers, DB Hoelzinger, TN Truong, LA Chew, A Myles, L Chaudhuri, ...
Oncotarget 8 (3), 5426, 2017
172017
Tetramethylpyrazine reduces epileptogenesis progression in electrical kindling models by modulating hippocampal excitatory neurotransmission
Y Jin, S Cai, Y Jiang, K Zhong, C Wen, Y Ruan, LA Chew, R Khanna, Z Xu, ...
ACS Chemical Neuroscience 10 (12), 4854-4863, 2019
152019
Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel (Cav2. 3) pathway to mediate spinal antinociception
L Martin, M Ibrahim, K Gomez, J Yu, S Cai, LA Chew, SS Bellampalli, ...
Pain 163 (9), 1751-1762, 2022
102022
Robust cone-mediated signaling persists late into rod photoreceptor degeneration
ML Scalabrino, M Thapa, LA Chew, E Zhang, J Xu, AP Sampath, J Chen, ...
Elife 11, e80271, 2022
82022
Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions
C Yu, EM Lad, R Mathew, S Littleton, Y Chen, K Schlepckow, S Degan, ...
bioRxiv, 2023
32023
Gene-agnostic approaches to treating inherited retinal degenerations
LA Chew, A Iannaccone
Frontiers in Cell and Developmental Biology 11, 1177838, 2023
32023
AAV gene augmentation of truncated complement factor h differentially rescues ocular complement dysregulation in a mouse model
D Grigsby, M Klingeborn, U Kelly, LA Chew, A Asokan, G Devlin, S Smith, ...
Investigative Ophthalmology & Visual Science 64 (10), 25-25, 2023
22023
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