| Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma L Gong, DLW Kwong, W Dai, P Wu, S Li, Q Yan, Y Zhang, B Zhang, ... Nature communications 12 (1), 1540, 2021 | 110 | 2021 |
| Systematic investigation of cytokine signaling activity at the tissue and single-cell levels P Jiang, Y Zhang, B Ru, Y Yang, T Vu, R Paul, A Mirza, G Altan-Bonnet, ... Nature methods 18 (10), 1181-1191, 2021 | 89 | 2021 |
| FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma Y Wang, Z Lyu, Y Qin, X Wang, L Sun, Y Zhang, L Gong, S Wu, S Han, ... Theranostics 10 (25), 11535, 2020 | 87 | 2020 |
| Cytokine and chemokine signals of T-cell exclusion in tumors Y Zhang, X Guan, P Jiang Frontiers in immunology 11, 594609, 2020 | 83 | 2020 |
| ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling Q Yan, L Jiang, M Liu, D Yu, Y Zhang, Y Li, S Fang, Y Li, YH Zhu, YF Yuan, ... Cancer research 77 (21), 5831-5845, 2017 | 73 | 2017 |
| Cancer cell reprogramming: a promising therapy converting malignancy to benignity L Gong, Q Yan, Y Zhang, X Fang, B Liu, X Guan Cancer communications 39, 1-13, 2019 | 68 | 2019 |
| C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism Y Zhang, Q Yan, L Gong, H Xu, B Liu, X Fang, D Yu, L Li, T Wei, Y Wang, ... Oncogene 40 (6), 1147-1161, 2021 | 54 | 2021 |
| A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets M Liu, Q Yan, Y Sun, Y Nam, L Hu, JHC Loong, Q Ouyang, Y Zhang, HL Li, ... Proceedings of the National Academy of Sciences 117 (11), 6103-6113, 2020 | 45 | 2020 |
| AT cell resilience model associated with response to immunotherapy in multiple tumor types Y Zhang, T Vu, DC Palmer, RJ Kishton, L Gong, J Huang, T Nguyen, ... Nature medicine 28 (7), 1421-1431, 2022 | 32 | 2022 |
| PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors Q Yan, Y Zhang, X Fang, B Liu, TL Wong, L Gong, S Liu, D Yu, M Liu, ... Cell Death & Differentiation 28 (6), 1955-1970, 2021 | 21 | 2021 |
| Estimation of cell lineages in tumors from spatial transcriptomics data B Ru, J Huang, Y Zhang, K Aldape, P Jiang Nature Communications 14 (1), 568, 2023 | 19 | 2023 |
| ISL1 promoted tumorigenesis and EMT via Aurora kinase A-induced activation of PI3K/AKT signaling pathway in neuroblastoma M Li, C Sun, X Bu, Y Que, L Zhang, Y Zhang, L Zhang, S Lu, J Huang, ... Cell death & disease 12 (6), 620, 2021 | 19 | 2021 |
| Targeting TROY-mediated P85a/AKT/TBX3 signaling attenuates tumor stemness and elevates treatment response in hepatocellular carcinoma B Liu, X Fang, DLW Kwong, Y Zhang, K Verhoeft, L Gong, B Zhang, ... Journal of Experimental & Clinical Cancer Research 41 (1), 182, 2022 | 15 | 2022 |
| Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction L Gong, J Luo, Y Zhang, Y Yang, S Li, X Fang, B Zhang, J Huang, ... Nature Communications 14 (1), 1912, 2023 | 14 | 2023 |
| KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis B Chen, H Chen, S Lu, X Zhu, Y Que, Y Zhang, J Huang, L Zhang, ... Cell Death & Disease 13 (4), 354, 2022 | 14 | 2022 |
| Elevated expression of RIT1 hyperactivates RAS/MAPK signal and sensitizes hepatocellular carcinoma to combined treatment with sorafenib and AKT inhibitor L Sun, S Xi, Z Zhou, F Zhang, P Hu, Y Cui, S Wu, Y Wang, S Wu, Y Wang, ... Oncogene 41 (5), 732-744, 2022 | 12 | 2022 |
| Recurrent ZNF83-E293V mutation promotes bladder cancer progression through the NF-κB pathway via transcriptional dysregulation of S100A8 ZJ Lyu, Y Wang, JL Huang, M Chen, SY Wu, Q Yan, Y Zhang, Y Tang, ... Molecular Therapy 29 (1), 275-290, 2021 | 8 | 2021 |
| Enhanced mitophagy driven by ADAR1-GLI1 editing supports the self-renewal of cancer stem cells in HCC J Luo, L Gong, Y Yang, Y Zhang, Q Liu, L Bai, X Fang, B Zhang, J Huang, ... Hepatology 79 (1), 61-78, 2024 | 6 | 2024 |
| Inhibition of lysyl oxidase‐like 2 overcomes adhesion‐dependent drug resistance in the collagen‐enriched liver cancer microenvironment L Gong, Y Zhang, Y Yang, Q Yan, J Ren, J Luo, YC Tiu, X Fang, B Liu, ... Hepatology Communications 6 (11), 3194-3211, 2022 | 4 | 2022 |
| GLIPR1 promotes proliferation, metastasis and 5-fluorouracil resistance in hepatocellular carcinoma by activating the PI3K/PDK1/ROCK1 pathway YC Tiu, L Gong, Y Zhang, J Luo, Y Yang, Y Tang, W Lee, XY Guan Cancer Gene Therapy 29 (11), 1720-1730, 2022 | 3 | 2022 |
GUAN Xin-YuanThe University of Hong KongVerified email at hku.hk
