| Linking crystallographic model and data quality PA Karplus, K Diederichs Science 336 (6084), 1030-1033, 2012 | 1967 | 2012 |
| Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling ZA Wood, LB Poole, PA Karplus Science 300 (5619), 650-653, 2003 | 1588 | 2003 |
| Prediction of chain flexibility in proteins: a tool for the selection of peptide antigens PA Karplus, GE Schulz Naturwissenschaften 72 (4), 212-213, 1985 | 1524 | 1985 |
| Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin GD Van Duyne, RF Standaert, PA Karplus, SL Schreiber, J Clardy Journal of molecular biology 229 (1), 105-124, 1993 | 1451 | 1993 |
| Improved R-factors for diffraction data analysis in macromolecular crystallography K Diederichs, PA Karplus Nature structural biology 4 (4), 269-275, 1997 | 1145 | 1997 |
| The crystal structure of urease from Klebsiella aerogenes E Jabri, MB Carr, RP Hausinger, PA Karplus Science 268 (5213), 998-1004, 1995 | 1075 | 1995 |
| Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex GD Van Duyne, RF Standaert, PA Karplus, SL Schreiber, J Clardy Science 252 (5007), 839-842, 1991 | 781 | 1991 |
| Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain MA Pearson, D Reczek, A Bretscher, PA Karplus Cell 101 (3), 259-270, 2000 | 758 | 2000 |
| Protein sulfenic acids in redox signaling LB Poole, PA Karplus, A Claiborne Annu. Rev. Pharmacol. Toxicol. 44, 325-347, 2004 | 724 | 2004 |
| Atomic structure of ferredoxin-NADP+ reductase: prototype for a structurally novel flavoenzyme family PA Karplus, MJ Daniels, JR Herriott Science 251 (4989), 60, 1991 | 685 | 1991 |
| Refined structure of glutathione reductase at 1.54 Å resolution PA Karplus, GE Schulz Journal of molecular biology 195 (3), 701-729, 1987 | 654 | 1987 |
| A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase MC Myzak, PA Karplus, FL Chung, RH Dashwood Cancer research 64 (16), 5767-5774, 2004 | 608 | 2004 |
| Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling A Perkins, KJ Nelson, D Parsonage, LB Poole, PA Karplus Trends in biochemical sciences 40 (8), 435-445, 2015 | 584 | 2015 |
| Typical 2‐Cys peroxiredoxins–structures, mechanisms and functions A Hall, PA Karplus, LB Poole The FEBS journal 276 (9), 2469-2477, 2009 | 518 | 2009 |
| Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca J Sakon, D Irwin, DB Wilson, PA Karplus Nature structural biology 4 (10), 810-818, 1997 | 485 | 1997 |
| 70 years of crystalline urease: what have we learned? PA Karplus, MA Pearson, RP Hausinger Accounts of Chemical Research 30 (8), 330-337, 1997 | 465 | 1997 |
| Dimers to Doughnuts: Redox-Sensitive Oligomerization of 2-Cysteine Peroxiredoxins, ZA Wood, LB Poole, RR Hantgan, PA Karplus Biochemistry 41 (17), 5493-5504, 2002 | 439 | 2002 |
| Cysteine-based redox switches in enzymes C Klomsiri, PA Karplus, LB Poole Antioxidants & redox signaling 14 (6), 1065-1077, 2011 | 424 | 2011 |
| Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2Å resolution PA Karplus, GE Schulz Journal of molecular biology 210 (1), 163-180, 1989 | 399 | 1989 |
| Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins A Hall, K Nelson, LB Poole, PA Karplus Antioxidants & redox signaling 15 (3), 795-815, 2011 | 373 | 2011 |
Kay DiederichsProfessor, Molecular Bioinformatics, University of KonstanzVerified email at uni-konstanz.de
