| Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers CL Dominguez, DH Floyd, A Xiao, GR Mullins, BA Kefas, W Xin, ... Cancer discovery 3 (7), 782-797, 2013 | 110 | 2013 |
| Discovery of novel Myc− Max heterodimer disruptors with a three-dimensional pharmacophore model G Mustata, AV Follis, DI Hammoudeh, SJ Metallo, H Wang, ... Journal of medicinal chemistry 52 (5), 1247-1250, 2009 | 103 | 2009 |
| Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen ER Sharlow, D Close, T Shun, S Leimgruber, R Reed, G Mustata, P Wipf, ... PLoS neglected tropical diseases 3 (11), e540, 2009 | 80 | 2009 |
| Approaches to oral drug delivery for challenging molecules G Mustata, SM Dinh Critical Reviews™ in Therapeutic Drug Carrier Systems 23 (2), 2006 | 78 | 2006 |
| Discovery of modulators of protein-protein interactions: current approaches and limitations L MC Meireles, G Mustata Current topics in medicinal chemistry 11 (3), 248-257, 2011 | 71 | 2011 |
| A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity ER Sharlow, TA Lyda, HC Dodson, G Mustata, MT Morris, SS Leimgruber, ... PLoS neglected tropical diseases 4 (4), e659, 2010 | 71 | 2010 |
| Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death G Mustata, M Li, N Zevola, A Bakan, L Zhang, M Epperly, J S Greenberger, ... Current topics in medicinal chemistry 11 (3), 281-290, 2011 | 67 | 2011 |
| HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors GI Mustata, A Brigo, JM Briggs Bioorganic & medicinal chemistry letters 14 (6), 1447-1454, 2004 | 63 | 2004 |
| Comparative molecular dynamics simulations of HIV‐1 integrase and the T66I/M154I mutant: Binding modes and drug resistance to a diketo acid inhibitor A Brigo, KW Lee, F Fogolari, GI Mustata, JM Briggs PROTEINS: Structure, Function, and Bioinformatics 59 (4), 723-741, 2005 | 59 | 2005 |
| Crystal structure at 1.45 Å resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms P LeMagueres, H Im, A Dvorak, U Strych, M Benedik, KL Krause Biochemistry 42 (50), 14752-14761, 2003 | 55 | 2003 |
| Comparison of multiple molecular dynamics trajectories calculated for the drug-resistant HIV-1 integrase T66I/M154I catalytic domain A Brigo, KW Lee, GI Mustata, JM Briggs Biophysical journal 88 (5), 3072-3082, 2005 | 52 | 2005 |
| Cluster analysis of water molecules in alanine racemase and their putative structural role G Mustata, JM Briggs Protein Engineering Design and Selection 17 (3), 223-234, 2004 | 51 | 2004 |
| Pathways of ligand clearance in acetylcholinesterase by multiple copy sampling SJW Daniel Van Belle, Leonardo De Maria, Gabriela Iurcu Journal of Molecular Biology 4 (12), 705-726, 2000 | 49* | 2000 |
| The crystal structure of Trichomonas vaginalis ferredoxin provides insight into metronidazole activation CR Crossnoe, JP Germanas, P LeMagueres, G Mustata, KL Krause Journal of molecular biology 318 (2), 503-518, 2002 | 47 | 2002 |
| Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19) Y Muftuoglu, G Mustata Bioorganic & medicinal chemistry letters 20 (10), 3050-3064, 2010 | 46 | 2010 |
| Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation J Zhao, L Zhang, X Mu, C Doebelin, W Nguyen, C Wallace, DP Reay, ... PLoS biology 16 (6), e2004663, 2018 | 42 | 2018 |
| Identification and characterization of a novel small-molecule inhibitor of β-catenin signaling ER Delgado, J Yang, J So, M Fanti, S Leimgruber, M Kahn, T Ishitani, ... The American journal of pathology 184 (7), 2111-2122, 2014 | 37 | 2014 |
| Interprofessional education: Lessons learned from conducting an electronic health record assignment JL Titzer, CF Swenty, G Mustata Wilson Journal of Interprofessional Care 29 (6), 536-540, 2015 | 34 | 2015 |
| HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines PA Johnston, M Sen, Y Hua, DP Camarco, TY Shun, JS Lazo, GM Wilson, ... Assay and drug development technologies 13 (7), 356-376, 2015 | 34 | 2015 |
| Development and implementation of a high-throughput high-content screening assay to identify inhibitors of androgen receptor nuclear localization in castration-resistant … PA Johnston, MM Nguyen, JA Dar, J Ai, Y Wang, KZ Masoodi, T Shun, ... Assay and drug development technologies 14 (4), 226-239, 2016 | 32 | 2016 |
James M. BriggsProfessor of Biochemistry, University of HoustonVerified email at uh.edu
