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Edkins Adrienne Lesley
Edkins Adrienne Lesley
Biomedical Biotechnology Research Unit, Department of Biochemistry and Microbiology
Verified email at ru.ac.za
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Cited by
Cited by
Year
The African coelacanth genome provides insights into tetrapod evolution
CT Amemiya, J Alföldi, AP Lee, S Fan, H Philippe, I MacCallum, I Braasch, ...
Nature 496 (7445), 311-316, 2013
7432013
CD23/FcεRII: molecular multi-tasking
M Acharya, G Borland, AL Edkins, LM Maclellan, J Matheson, BW Ozanne, ...
Clinical & Experimental Immunology 162 (1), 12-23, 2010
2252010
Cancer stem cells in breast cancer and metastasis
JC Lawson, GL Blatch, AL Edkins
Breast cancer research and treatment 118, 241-254, 2009
1752009
Human DNAJ in cancer and stem cells
JN Sterrenberg, GL Blatch, AL Edkins
Cancer letters 312 (2), 129-142, 2011
1222011
CHIP: a co-chaperone for degradation by the proteasome
AL Edkins
The Networking of Chaperones by Co-chaperones: Control of Cellular Protein …, 2015
1062015
Cytotoxicity of lapachol, β-lapachone and related synthetic 1, 4-naphthoquinones against oesophageal cancer cells
SN Sunassee, CGL Veale, N Shunmoogam-Gounden, O Osoniyi, ...
European Journal of Medicinal Chemistry 62, 98-110, 2013
802013
Quinones and halogenated monoterpenes of algal origin show anti-proliferative effects against breast cancer cells in vitro
JA de la Mare, JC Lawson, MT Chiwakata, DR Beukes, AL Edkins, ...
Investigational New Drugs 30, 2187-2200, 2012
752012
Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells
MC Hunter, KL O’Hagan, A Kenyon, KCH Dhanani, E Prinsloo, AL Edkins
PloS one 9 (1), e86842, 2014
742014
Breast cancer: current developments in molecular approaches to diagnosis and treatment
JA de la Mare, L Contu, M C Hunter, B Moyo, J N Sterrenberg, ...
Recent patents on anti-cancer drug discovery 9 (2), 153-175, 2014
702014
Hsp70/Hsp90 organising protein (hop): beyond interactions with chaperones and prion proteins
S Baindur-Hudson, AL Edkins, GL Blatch
The Networking of Chaperones by Co-chaperones: Control of Cellular Protein …, 2015
612015
Heat shock proteins as modulators and therapeutic targets of chronic disease: an integrated perspective
AL Edkins, JT Price, AG Pockley, GL Blatch
Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018
532018
Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay
JA de la Mare, JN Sterrenberg, MG Sukhthankar, MT Chiwakata, ...
Cancer Cell International 13, 1-14, 2013
532013
Fucoidan structure and its impact on glucose metabolism: Implications for diabetes and cancer therapy
B Mabate, CD Daub, S Malgas, AL Edkins, BI Pletschke
Marine drugs 19 (1), 30, 2021
522021
Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model
JA de la Mare, T Jurgens, AL Edkins
BMC cancer 17, 1-16, 2017
452017
Real-time monitoring of 3T3-L1 preadipocyte differentiation using a commercially available electric cell-substrate impedance sensor system
AH Kramer, J Joos-Vandewalle, AL Edkins, CL Frost, E Prinsloo
Biochemical and biophysical research communications 443 (4), 1245-1250, 2014
432014
STAT3 interacts directly with Hsp90
E Prinsloo, AH Kramer, AL Edkins, GL Blatch
IUBMB life 64 (3), 266-273, 2012
412012
The palladacycle, AJ-5, exhibits anti-tumour and anti-cancer stem cell activity in breast cancer cells
S Aliwaini, J Peres, WL Kröger, A Blanckenberg, J de La Mare, AL Edkins, ...
Cancer Letters 357 (1), 206-218, 2015
402015
Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines
T Willmer, L Contu, GL Blatch, AL Edkins
Cancer letters 328 (2), 252-260, 2013
372013
A Trypanosoma cruzi heat shock protein 40 is able to stimulate the adenosine triphosphate hydrolysis activity of heat shock protein 70 and can substitute for a yeast heat shock …
AL Edkins, MH Ludewig, GL Blatch
The International Journal of Biochemistry & Cell Biology 36 (8), 1585-1598, 2004
372004
Ferrocenyl and organic novobiocin derivatives: Synthesis and their in vitro biological activity
M Mbaba, AN Mabhula, N Boel, AL Edkins, M Isaacs, HC Hoppe, ...
Journal of inorganic biochemistry 172, 88-93, 2017
352017
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