Highly selective inhibition of IMPDH2 provides the basis of antineuroinflammation therapy LX Liao, XM Song, LC Wang, HN Lv, JF Chen, D Liu, G Fu, MB Zhao, ... Proceedings of the National Academy of Sciences 114 (29), E5986-E5994, 2017 | 115 | 2017 |
Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity L Wang, B Wang, NS Gasek, Y Zhou, RL Cohn, DE Martin, W Zuo, ... Cell metabolism 34 (1), 75-89. e8, 2022 | 98 | 2022 |
An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo B Wang, L Wang, NS Gasek, Y Zhou, T Kim, C Guo, ER Jellison, ... Nature aging 1 (10), 962-973, 2021 | 79 | 2021 |
Transplanting cells from old but not young donors causes physical dysfunction in older recipients B Wang, Z Liu, VP Chen, L Wang, CL Inman, Y Zhou, C Guo, T Tchkonia, ... Aging cell 19 (3), e13106, 2020 | 53 | 2020 |
Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity KW Zeng, JK Wang, LC Wang, Q Guo, TT Liu, FJ Wang, N Feng, ... Signal transduction and targeted therapy 6 (1), 71, 2021 | 46 | 2021 |
Senolytics improve bone forming potential of bone marrow mesenchymal stem cells from aged mice Y Zhou, X Xin, L Wang, B Wang, L Chen, O Liu, DW Rowe, M Xu NPJ Regenerative medicine 6 (1), 34, 2021 | 45 | 2021 |
Highly selective activation of heat shock protein 70 by allosteric regulation provides an insight into efficient neuroinflammation inhibition LC Wang, LX Liao, HN Lv, D Liu, W Dong, J Zhu, JF Chen, ML Shi, G Fu, ... EBioMedicine 23, 160-172, 2017 | 41 | 2017 |
Integration of metabolomics with pharmacodynamics to elucidate the anti-myocardial ischemia effects of combination of notoginseng total saponins and safflower total flavonoids Y Meng, Z Du, Y Li, L Wang, P Gao, X Gao, C Li, M Zhao, Y Jiang, P Tu, ... Frontiers in Pharmacology 9, 667, 2018 | 32 | 2018 |
An integrated proteomics and bioinformatics approach reveals the anti-inflammatory mechanism of carnosic acid LC Wang, WH Wei, XW Zhang, D Liu, KW Zeng, PF Tu Frontiers in pharmacology 9, 370, 2018 | 32 | 2018 |
Protosappanin A exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia W Li-Chao, L Li-Xi, Z Ming-Bo, D Xin, Z Ke-Wu, TU Peng-Fei Chinese journal of natural medicines 15 (9), 674-679, 2017 | 19 | 2017 |
Total saponins of Albiziae Cortex show anti-hepatoma carcinoma effects by inducing S phase arrest and mitochondrial apoptosis pathway activation Y Qian, QH Han, LC Wang, Q Guo, XD Wang, PF Tu, KW Zeng, H Liang Journal of Ethnopharmacology 221, 20-29, 2018 | 17 | 2018 |
A standardized notoginseng extract exerts cardioprotection by attenuating apoptosis under endoplasmic reticulum stress conditions LC Wang, WS Zhang, Q Liu, J Li, RN Alolga, K Liu, BL Liu, P Li, LW Qi Journal of functional foods 16, 20-27, 2015 | 13 | 2015 |
TARGETING OF P21CIP1-HIGHLY-EXPRESSING CELLS ALLEVIATES NEUROPSYCHIATRIC DISORDERS WITH OBESITY L Wang, B Wang, N Gasek, M Xu Innovation in Aging 7 (Suppl 1), 1127, 2023 | | 2023 |
Macrophage activation by low molecular weight saccharides from Cistanche deserticola YH Zhang, LC Wang, PF Tu, KW Zeng, Y Jiang Zhongguo Zhong yao za zhi= Zhongguo Zhongyao Zazhi= China Journal of Chinese …, 2017 | | 2017 |
Targets identification and mechanism analysis for macrophage activation of low molecular weight saccharides from Cistanche deserticola based on molecular affinity chromatography LC Wang, D Liu, Y Jiang, PF Tu, KW Zeng Zhongguo Zhong yao za zhi= Zhongguo Zhongyao Zazhi= China Journal of Chinese …, 2017 | | 2017 |