| Structure of the adenosine-bound human adenosine A1 receptor–Gi complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 320 | 2018 |
| Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist C Valant, LT May, L Aurelio, CH Chuo, PJ White, JA Baltos, PM Sexton, ... Proceedings of the National Academy of Sciences 111 (12), 4614-4619, 2014 | 116 | 2014 |
| Dominant negative G proteins enhance formation and purification of agonist-GPCR-G protein complexes for structure determination YL Liang, P Zhao, C Draper-Joyce, JA Baltos, A Glukhova, TT Truong, ... ACS pharmacology & translational science 1 (1), 12-20, 2018 | 92 | 2018 |
| Quantification of adenosine A1 receptor biased agonism: Implications for drug discovery JA Baltos, KJ Gregory, PJ White, PM Sexton, A Christopoulos, LT May Biochemical pharmacology 99, 101-112, 2016 | 68 | 2016 |
| Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor M Korczynska, MJ Clark, C Valant, J Xu, EV Moo, S Albold, DR Weiss, ... Proceedings of the National Academy of Sciences 115 (10), E2419-E2428, 2018 | 66 | 2018 |
| Extracellular loop 2 of the adenosine A1 receptor has a key role in orthosteric ligand affinity and agonist efficacy ATN Nguyen, JA Baltos, T Thomas, TD Nguyen, LL Muñoz, KJ Gregory, ... Molecular Pharmacology 90 (6), 703-714, 2016 | 56 | 2016 |
| New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism EA Vecchio, JA Baltos, ATN Nguyen, A Christopoulos, PJ White, LT May British journal of pharmacology 175 (21), 4036-4046, 2018 | 54 | 2018 |
| Capadenoson, a clinically trialed partial adenosine A1 receptor agonist, can stimulate adenosine A2B receptor biased agonism JA Baltos, EA Vecchio, MA Harris, CX Qin, RH Ritchie, A Christopoulos, ... Biochemical pharmacology 135, 79-89, 2017 | 47 | 2017 |
| Structure-activity analysis of biased agonism at the human adenosine A3 receptor JA Baltos, S Paoletta, ATN Nguyen, KJ Gregory, DK Tosh, ... Molecular pharmacology 90 (1), 12-22, 2016 | 43 | 2016 |
| The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling EA Vecchio, CH Chuo, JA Baltos, L Ford, PJ Scammells, BH Wang, ... Biochemical pharmacology 117, 46-56, 2016 | 39 | 2016 |
| A Structure–Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists L Aurelio, JA Baltos, L Ford, ATN Nguyen, M Jorg, SM Devine, C Valant, ... Journal of medicinal chemistry 61 (5), 2087-2103, 2018 | 28 | 2018 |
| Biased agonism at adenosine receptors SM McNeill, JA Baltos, PJ White, LT May Cellular Signalling 82, 109954, 2021 | 23 | 2021 |
| α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes M Sato, BA Evans, AL Sandström, LY Chia, S Mukaida, B San Thai, ... Biochemical Pharmacology 148, 27-40, 2018 | 23 | 2018 |
| A robust method for particulate detection of a genetic tag for 3D electron microscopy J Rae, C Ferguson, N Ariotti, RI Webb, HH Cheng, JL Mead, JD Riches, ... Elife 10, e64630, 2021 | 17 | 2021 |
| Adenosine receptor signalling in Alzheimer’s disease PNH Trinh, JA Baltos, SD Hellyer, LT May, KJ Gregory Purinergic signalling 18 (3), 359-381, 2022 | 7 | 2022 |
| Structure-based virtual screening discovers potent and selective adenosine A1 receptor antagonists P Matricon, ATN Nguyen, DD Vo, JA Baltos, M Jaiteh, A Luttens, ... European Journal of Medicinal Chemistry 257, 115419, 2023 | 6 | 2023 |
| The role of the adenosine system in epilepsy and its comorbidities JA Baltos, PM Casillas‐Espinosa, B Rollo, KJ Gregory, PJ White, ... British Journal of Pharmacology, 2023 | 5 | 2023 |
| Small molecule allosteric modulation of the adenosine A1 receptor ATN Nguyen, QL Tran, JA Baltos, SM McNeill, DTN Nguyen, LT May Frontiers in Endocrinology 14, 1184360, 2023 | 3 | 2023 |
| APEX-gold: a genetically-encoded particulate marker for robust 3D electron microscopy J Rae, C Ferguson, N Ariotti, RI Webb, HH Cheng, JL Mead, J Riches, ... bioRxiv, 2020.10. 06.328831, 2020 | 1 | 2020 |
| Adenosine G Protein‐Coupled Receptor Biased Agonism to Treat Ischemic Heart Disease LT May, JA Baltos, CH Chuo, EA Vecchio, BH Wang, AR Kompa, ... The FASEB Journal 32, 555.19-555.19, 2018 | 1 | 2018 |
