Characterization of the lipidomic profile of human coronavirus-infected cells: implications for lipid metabolism remodeling upon coronavirus replication B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan, H Shuai, Y Wang, ... Viruses 11 (1), 73, 2019 | 259 | 2019 |
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 232 | 2019 |
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 S Yuan, X Yin, X Meng, JFW Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Nature 593 (7859), 418-423, 2021 | 181 | 2021 |
Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target S Yuan, H Chu, J Huang, X Zhao, ZW Ye, PM Lai, L Wen, JP Cai, Y Mo, ... Science advances 6 (35), eaba7910, 2020 | 52 | 2020 |
Lipidomic profiling reveals significant perturbations of intracellular lipid homeostasis in enterovirus-infected cells B Yan, Z Zou, H Chu, G Chan, JOL Tsang, PM Lai, S Yuan, CCY Yip, ... International journal of molecular sciences 20 (23), 5952, 2019 | 37 | 2019 |
Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication. Viruses 2019, 11, 73 B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan, H Shuai, Y Wang, ... DOI: https://doi. org/10.3390/v11010073. PMID: https://www. ncbi. nlm. nih …, 0 | 29 | |
Identification of a nonaketide product for the iterative polyketide synthase in biosynthesis of the nine‐membered enediyne C‐1027 X Chen, ZF Guo, PM Lai, KH Sze, Z Guo Angewandte Chemie 43 (122), 8098-8100, 2010 | 18 | 2010 |
Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters S Yuan, X Yin, XZ Meng, J Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Research square, 2020 | 16 | 2020 |
Talaromyces marneffei Mp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts WH Lam, KH Sze, Y Ke, MK Tse, H Zhang, PCY Woo, SKP Lau, CCY Lau, ... Infection and Immunity 87 (4), 10.1128/iai. 00679-18, 2019 | 14 | 2019 |
Phosphatidic acid phosphatase 1 impairs SARS-CoV-2 replication by affecting the glycerophospholipid metabolism pathway B Yan, S Yuan, J Cao, K Fung, PM Lai, F Yin, KH Sze, Z Qin, Y Xie, ZW Ye, ... International Journal of Biological Sciences 18 (12), 4744, 2022 | 12 | 2022 |
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Nat Commun 10: 120 S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... | 10 | 2019 |
Characterization of the lipidomic profile of human coronavirus-infected cells: implications for lipid metabolism remodeling upon coronavirus replication. Viruses 11 (1): 73 B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan, H Shuai, Y Wang, ... | 7 | 2019 |
Probing protein dynamics by nuclear magnetic resonance K Hung Sze, P Man Lai Protein and peptide letters 18 (4), 373-379, 2011 | 5 | 2011 |
Linoleic acid metabolism activation in macrophages promotes the clearing of intracellular Staphylococcus aureus B Yan, K Fung, S Ye, PM Lai, YX Wei, KH Sze, D Yang, P Gao, RYT Kao Chemical Science 13 (42), 12445-12460, 2022 | 4 | 2022 |
SaeR as a novel target for antivirulence therapy against Staphylococcus aureus P Gao, Y Wei, S Hou, PM Lai, H Liu, SSC Tai, VYM Tang, PH Prakash, ... Emerging Microbes & Infections 12 (2), 2254415, 2023 | 2 | 2023 |
Identification of a Small Molecule Compound Active against Antibiotic-Tolerant Staphylococcus aureus by Boosting ATP Synthesis HTV Iu, PM Fong, HCB Yam, P Gao, B Yan, PM Lai, VYM Tang, KH Li, ... International Journal of Molecular Sciences 24 (7), 6242, 2023 | | 2023 |
In Silico Structure-Based Screening of Large Ligand Library Against Virulence Factors of Drug Resistant Pathogens TTM Yung, PM Lai, T Zhou, MK Tse, RYT Kao, KY Yuen, KH Sze Biomedical Journal of Scientific & Technical Research 18 (5), 13848-13854B, 2019 | | 2019 |
Structure determination of N-terminal peptide of nucleoprotein (NP20) of influenza virus H5N1 by nuclear magnetic resonance spectroscopy P Lai HKU Theses Online (HKUTO), 2013 | | 2013 |
Characterization of a nonaketide precursor in biosynthesis of the nine-membered enediyne core of the antitumor antibiotic C-1027 X Chen, ZF Guo, PM Lai, KH Sze, Z Guo The Seventeenth Symposium on Chemistry Postgraduate Research in Hong Kong, 2010 | | 2010 |
Structure And Functional Study of N-terminal of Nucleoprotein (NP-20) PM Lai, PC Shaw, KH Sze Symposium on Chemistry Postgraduate Research in Hong Kong, 2009 | | 2009 |