Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes SP Schröder, C De Boer, NGS McGregor, RJ Rowland, O Moroz, ... ACS central science 5 (6), 1067-1078, 2019 | 48 | 2019 |
Functionalized cyclophellitols are selective glucocerebrosidase inhibitors and induce a bona fide neuropathic Gaucher model in zebrafish M Artola, CL Kuo, LT Lelieveld, RJ Rowland, GA van der Marel, ... Journal of the American Chemical Society 141 (10), 4214-4218, 2019 | 37 | 2019 |
α-d-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal α-galactosidase A in Fabry disease M Artola, C Hedberg, RJ Rowland, L Raich, K Kytidou, L Wu, A Schaaf, ... Chemical Science 10 (40), 9233-9243, 2019 | 17 | 2019 |
A baculoviral system for the production of human β-glucocerebrosidase enables atomic resolution analysis RJ Rowland, L Wu, F Liu, GJ Davies Acta Crystallographica Section D: Structural Biology 76 (6), 565-580, 2020 | 8 | 2020 |
Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents RJ Rowland, Y Chen, I Breen, L Wu, WA Offen, TJM Beenakker, Q Su, ... Chemistry-a European Journal 27, 16377-16388, 2021 | 7 | 2021 |
Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1 RJ Rowland, R Heath, D Maskell, RF Thompson, NA Ranson, JN Blaza, ... Scientific reports 13 (1), 10718, 2023 | 3 | 2023 |
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex RJ Rowland, S Korolchuk, M Salamina, JR Ault, S Hart, JP Turkenberg, ... bioRxiv, 2023.10. 17.562665, 2023 | | 2023 |
Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha-and beta-glucosidases D van der Gracht, RJ Rowland, V Roig-Zamboni, MJ Ferraz, M Louwerse, ... Chemical Science 14 (34), 9136-9144, 2023 | | 2023 |
Structural and functional characterisation of human lysosomal glycoside hydrolases: insights into lysosomal storage disorders RJ Rowland University of York, 2021 | | 2021 |
Pharmacological modulation of glycosidases in zebrafish CL Kuo, WW Kallemeijn, LT Lelieveld, M Mirzaian, I Zoutendijk, A Vardi, ... FEBS J 286 (3), 584-600, 2019 | | 2019 |
Synthesis and Biochemical Evaluation of Bifunctional Cyclophellitol Aziridines as Selective GBA Inhibitors and Activity-Based Probes RJ Rowland, Y Chen, I Breen, L Wu, WA Offen, TJ Beenakker, Q Su, ... Exploring chemical space in covalent and competitive glycosidase inhibitor …, 0 | | |
Activity-based probes targeting glycosidases acting on plant glycans SP Schröder, C de Boer, NGS McGregor, RJ Rowland, O Moroz, ... | | |