Polymeric micelles for nano-scale drug delivery K Miyata, RJ Christie, K Kataoka Reactive and Functional Polymers 71 (3), 227-234, 2011 | 518 | 2011 |
Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery Y Matsumoto, JW Nichols, K Toh, T Nomoto, H Cabral, Y Miura, ... Nature nanotechnology 11 (6), 533-538, 2016 | 407 | 2016 |
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery S Matsumoto, RJ Christie, N Nishiyama, K Miyata, A Ishii, M Oba, ... Biomacromolecules 10 (1), 119-127, 2009 | 374 | 2009 |
Polymeric micelles from poly (ethylene glycol)–poly (amino acid) block copolymer for drug and gene delivery K Osada, RJ Christie, K Kataoka Journal of The Royal Society Interface 6 (suppl_3), S325-S339, 2009 | 260 | 2009 |
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection RJ Christie, Y Matsumoto, K Miyata, T Nomoto, S Fukushima, K Osada, ... Acs Nano 6 (6), 5174-5189, 2012 | 220 | 2012 |
Design strategies to improve soluble macromolecular delivery constructs RJ Christie, DW Grainger Advanced drug delivery reviews 55 (3), 421-437, 2003 | 149 | 2003 |
Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors Y Oe, RJ Christie, M Naito, SA Low, S Fukushima, K Toh, Y Miura, ... Biomaterials 35 (27), 7887-7895, 2014 | 139 | 2014 |
Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles HJ Kim, H Takemoto, Y Yi, M Zheng, Y Maeda, H Chaya, K Hayashi, P Mi, ... ACS nano 8 (9), 8979-8991, 2014 | 137 | 2014 |
Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles F Pittella, K Miyata, Y Maeda, T Suma, S Watanabe, Q Chen, RJ Christie, ... Journal of controlled release 161 (3), 868-874, 2012 | 130 | 2012 |
Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides RJ Christie, R Fleming, B Bezabeh, R Woods, S Mao, J Harper, A Joseph, ... Journal of controlled release 220, 660-670, 2015 | 128 | 2015 |
Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery M Oba, K Miyata, K Osada, RJ Christie, M Sanjoh, W Li, S Fukushima, ... Biomaterials 32 (2), 652-663, 2011 | 118 | 2011 |
Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG T Suma, K Miyata, Y Anraku, S Watanabe, RJ Christie, H Takemoto, ... ACS nano 6 (8), 6693-6705, 2012 | 110 | 2012 |
Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines RJ Christie, K Miyata, Y Matsumoto, T Nomoto, D Menasco, TC Lai, ... Biomacromolecules 12 (9), 3174-3185, 2011 | 109 | 2011 |
Minireview: delivering the code: polyplex carriers for deoxyribonucleic acid and ribonucleic acid interference therapies RJ Christie, N Nishiyama, K Kataoka Endocrinology 151 (2), 466-473, 2010 | 98 | 2010 |
siRNA delivery from triblock copolymer micelles with spatially-ordered compartments of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core HJ Kim, K Miyata, T Nomoto, M Zheng, A Kim, X Liu, H Cabral, RJ Christie, ... Biomaterials 35 (15), 4548-4556, 2014 | 89 | 2014 |
Efficient preparation of site-specific antibody–drug conjugates using cysteine insertion N Dimasi, R Fleming, H Zhong, B Bezabeh, K Kinneer, RJ Christie, ... Molecular pharmaceutics 14 (5), 1501-1516, 2017 | 78 | 2017 |
Solution structure of the 3'-5'cyclic dinucleotide d (pApA). A combined NMR, UV melting, and molecular mechanics study. MJ Blommers, CA Haasnoot, JA Walters, GA Van der Marel, ... Biochemistry 27 (22), 8361-8369, 1988 | 77* | 1988 |
Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography Y Matsumoto, T Nomoto, H Cabral, Y Matsumoto, S Watanabe, ... Biomedical optics express 1 (4), 1209-1216, 2010 | 67 | 2010 |
Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles K Osada, T Shiotani, TA Tockary, D Kobayashi, H Oshima, S Ikeda, ... Biomaterials 33 (1), 325-332, 2012 | 66 | 2012 |
Dual environment-responsive polyplex carriers for enhanced intracellular delivery of plasmid DNA M Sanjoh, K Miyata, RJ Christie, T Ishii, Y Maeda, F Pittella, S Hiki, ... Biomacromolecules 13 (11), 3641-3649, 2012 | 65 | 2012 |