| Repeat instability as the basis for human diseases and as a potential target for therapy A López Castel, JD Cleary, CE Pearson Nature reviews Molecular cell biology 11 (3), 165-170, 2010 | 465 | 2010 |
| Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues A López Castel, M Nakamori, S Tome, D Chitayat, G Gourdon, ... Human molecular genetics 20 (1), 1-15, 2011 | 150 | 2011 |
| CpG methylation, a parent-of-origin effect for maternal-biased transmission of congenital myotonic dystrophy L Barbé, S Lanni, A López-Castel, S Franck, C Spits, K Keymolen, ... The American Journal of Human Genetics 100 (3), 488-505, 2017 | 99 | 2017 |
| Tissue-and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus JD Cleary, S Tomé, A López Castel, GB Panigrahi, L Foiry, KA Hagerman, ... Nature structural & molecular biology 17 (9), 1079-1087, 2010 | 69 | 2010 |
| Myotonic dystrophy type 1 drug development: A pipeline toward the market M Pascual-Gilabert, A López-Castel, R Artero Drug Discovery Today 26 (7), 1765-1772, 2021 | 53 | 2021 |
| CTG/CAG Repeat Instability Is Modulated by the Levels of Human DNA Ligase I and Its Interaction with Proliferating Cell Nuclear Antigen A DISTINCTION BETWEEN REPLICATION AND … AL Castel, AE Tomkinson, CE Pearson Journal of Biological Chemistry 284 (39), 26631-26645, 2009 | 51 | 2009 |
| Maternal germline-specific effect of DNA ligase I on CTG/CAG instability S Tomé, GB Panigrahi, A López Castel, L Foiry, DW Melton, G Gourdon, ... Human molecular genetics 20 (11), 2131-2143, 2011 | 46 | 2011 |
| MicroRNA-based therapeutic perspectives in myotonic dystrophy A Lopez Castel, SJ Overby, R Artero International journal of molecular sciences 20 (22), 5600, 2019 | 33 | 2019 |
| The myotonic dystrophy type 1 drug development pipeline: 2022 edition M Pascual-Gilabert, R Artero, A López-Castel Drug discovery today 28 (3), 103489, 2023 | 25 | 2023 |
| Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks MM Slean, GB Panigrahi, AL Castel, AB Pearson, AE Tomkinson, ... DNA repair 42, 107-118, 2016 | 21 | 2016 |
| Development of a Drosophila melanogaster spliceosensor system for in vivo high-throughput screening in myotonic dystrophy type 1 I García-Alcover, J Colonques-Bellmunt, R Garijo, JR Tormo, R Artero, ... Disease models & mechanisms 7 (11), 1297-1306, 2014 | 20 | 2014 |
| Germ cells microsatellite instability: The effect of different mutagens in a mismatch repair mutant of Drosophila (spel1) A López, N Xamena, R Marcos, A Velázquez Mutation Research/Genetic Toxicology and Environmental Mutagenesis 514 (1-2 …, 2002 | 20 | 2002 |
| Identification of restriction endonucleases sensitive to 5-cytosine methylation at non-CpG sites, including expanded (CAG) n/(CTG) n repeats A López Castel, M Nakamori, CA Thornton, CE Pearson Epigenetics 6 (4), 416-420, 2011 | 19 | 2011 |
| Analysis of Genomic Damage in the Mutagen-Sensitive mus-201 Mutant of Drosophila Melanogaster by Arbitrarily Primed PCR (AP-PCR) Fingerprinting A López, N Xamena, O Cabré, A Creus, R Marcos, A Velázquez Mutation Research 435 (1), 63-75, 1999 | 19 | 1999 |
| 3, 4-Dihydroxy-and 3, 4-methylenedioxy-phenanthrene-type alkaloids with high selectivity for D2 dopamine receptor L Moreno, N Cabedo, MD Ivorra, MJ Sanz, AL Castel, MC Álvarez, ... Bioorganic & medicinal chemistry letters 23 (17), 4824-4827, 2013 | 17 | 2013 |
| Replacement of the myotonic dystrophy type 1 CTG repeat with ‘non-CTG repeat’insertions in specific tissues MM Axford, A López-Castel, M Nakamori, CA Thornton, CE Pearson Journal of medical genetics 48 (7), 438-443, 2011 | 14 | 2011 |
| Six serum miRNAs fail to validate as myotonic dystrophy type 1 biomarkers JM Fernandez-Costa, B Llamusi, A Bargiela, M Zulaica, MC Alvarez-Abril, ... Plos one 11 (2), e0150501, 2016 | 12 | 2016 |
| Germline genomic instability in PCNA mutants of Drosophila: DNA fingerprinting and microsatellite analysis A López, N Xamena, R Marcos, A Velázquez Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 570 (2 …, 2005 | 12 | 2005 |
| Germline mutations at microsatellite loci in homozygous and heterozygous mutants for mismatch repair and PCNA genes in Drosophila A Baida, A López, R Marcos, A Velázquez DNA repair 2 (7), 827-833, 2003 | 12 | 2003 |
| (CCUG) n RNA toxicity in a Drosophila model of myotonic dystrophy type 2 (DM2) activates apoptosis VB Yenigun, M Sirito, A Amcheslavky, T Czernuszewicz, ... Disease models & mechanisms 10 (8), 993-1003, 2017 | 10 | 2017 |
Ruben ArteroUniversity of ValenciaVerified email at uv.es
