The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold KL Seley-Radtke, MK Yates Antiviral research 154, 66-86, 2018 | 508 | 2018 |
The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold MK Yates, KL Seley-Radtke Antiviral research 162, 5-21, 2019 | 250 | 2019 |
Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses L Eyer, R Nencka, E de Clercq, K Seley-Radtke, D Růžek Antiviral Chemistry and Chemotherapy 26, 2040206618761299, 2018 | 163 | 2018 |
Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity HL Peters, D Jochmans, AH de Wilde, CC Posthuma, EJ Snijder, J Neyts, ... Bioorganic & medicinal chemistry letters 25 (15), 2923-2926, 2015 | 97 | 2015 |
1-[2-(2-Benzoyl-and 2-benzylphenoxy) ethyl] uracils as potent anti-HIV-1 agents MS Novikov, ON Ivanova, AV Ivanov, AA Ozerov, VT Valuev-Elliston, ... Bioorganic & medicinal chemistry 19 (19), 5794-5802, 2011 | 84 | 2011 |
“Molecular chameleons”. Design and synthesis of a second series of flexible nucleosides KL Seley, S Salim, L Zhang, PI O'Daniel The Journal of Organic Chemistry 70 (5), 1612-1619, 2005 | 81 | 2005 |
“Fleximers”. Design and Synthesis of a New Class of Novel Shape-Modified Nucleosides1 KL Seley, L Zhang, A Hagos, S Quirk The Journal of Organic Chemistry 67 (10), 3365-3373, 2002 | 79 | 2002 |
Synthesis and antitumor activity of thieno-separated tricyclic purines KL Seley, P Januszczyk, A Hagos, L Zhang, DT Dransfield Journal of medicinal chemistry 43 (25), 4877-4883, 2000 | 68 | 2000 |
“Fleximers”. Design and synthesis of two novel split nucleosides KL Seley, L Zhang, A Hagos Organic Letters 3 (20), 3209-3210, 2001 | 66 | 2001 |
Recent advances in synthetic approaches for medicinal chemistry of C-nucleosides K Temburnikar, KL Seley-Radtke Beilstein Journal of Organic Chemistry 14 (1), 772-785, 2018 | 65 | 2018 |
Creation and discovery of ligand–receptor pairs for transcriptional control with small molecules LJ Schwimmer, P Rohatgi, B Azizi, KL Seley, DF Doyle Proceedings of the National Academy of Sciences 101 (41), 14707-14712, 2004 | 62 | 2004 |
A 5′-noraristeromycin enantiomer with activity towards hepatitis B virus KL Seley, SW Schneller, B Korba Nucleosides, Nucleotides & Nucleic Acids 16 (12), 2095-2099, 1997 | 60 | 1997 |
Conformational properties of shape modified nucleosides− fleximers M Polak, KL Seley, J Plavec Journal of the American Chemical Society 126 (26), 8159-8166, 2004 | 53 | 2004 |
Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside KL Seley, S Quirk, S Salim, L Zhang, A Hagos Bioorganic & medicinal chemistry letters 13 (12), 1985-1988, 2003 | 52 | 2003 |
N1, N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase MS Novikov, VT Valuev-Elliston, DA Babkov, MP Paramonova, AV Ivanov, ... Bioorganic & medicinal chemistry 21 (5), 1150-1158, 2013 | 50 | 2013 |
Thiophene-expanded guanosine analogues of gemcitabine Z Chen, TC Ku, KL Seley-Radtke Bioorganic & medicinal chemistry letters 25 (19), 4274-4276, 2015 | 47 | 2015 |
(+)-7-Deaza-5 ‘-noraristeromycin as an anti-trypanosomal agent KL Seley, SW Schneller, D Rattendi, CJ Bacchi Journal of medicinal chemistry 40 (4), 622-624, 1997 | 46 | 1997 |
Antiproliferative activities of halogenated thieno [3, 2-d] pyrimidines KW Temburnikar, SC Zimmermann, NT Kim, CR Ross, C Gelbmann, ... Bioorganic & medicinal chemistry 22 (7), 2113-2122, 2014 | 45 | 2014 |
Synthesis and anti-HCMV activity of 1-[ω-(phenoxy) alkyl] uracil derivatives and analogues thereof MS Novikov, DA Babkov, MP Paramonova, AL Khandazhinskaya, ... Bioorganic & medicinal chemistry 21 (14), 4151-4157, 2013 | 45 | 2013 |
Substrate discrimination by the human GTP fucose pyrophosphorylase S Quirk, KL Seley Biochemistry 44 (32), 10854-10863, 2005 | 43 | 2005 |