Human placental trophoblasts confer viral resistance to recipient cells E Delorme-Axford, RB Donker, JF Mouillet, T Chu, A Bayer, Y Ouyang, ... Proceedings of the National Academy of Sciences 110 (29), 12048-12053, 2013 | 507 | 2013 |
Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling SN Sarkar, KL Peters, CP Elco, S Sakamoto, S Pal, GC Sen Nature structural & molecular biology 11 (11), 1060-1067, 2004 | 461 | 2004 |
Transcriptional signaling by double-stranded RNA: role of TLR3 GC Sen, SN Sarkar Cytokine & growth factor reviews 16 (1), 1-14, 2005 | 354 | 2005 |
Porcine reproductive and respiratory syndrome virus nonstructural protein 1β modulates host innate immune response by antagonizing IRF3 activation LK Beura, SN Sarkar, B Kwon, S Subramaniam, C Jones, AK Pattnaik, ... Journal of virology 84 (3), 1574-1584, 2010 | 342 | 2010 |
Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor J Zhu, Y Zhang, A Ghosh, RA Cuevas, A Forero, J Dhar, MS Ibsen, ... Immunity 40 (6), 936-948, 2014 | 253 | 2014 |
STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment T Ohkuri, A Ghosh, A Kosaka, J Zhu, M Ikeura, M David, SC Watkins, ... Cancer immunology research 2 (12), 1199-1208, 2014 | 221 | 2014 |
Crystal structure of the 2′-specific and double-stranded RNA-activated interferon-induced antiviral protein 2′-5′-oligoadenylate synthetase R Hartmann, J Justesen, SN Sarkar, GC Sen, VC Yee Molecular cell 12 (5), 1173-1185, 2003 | 211 | 2003 |
Differential activation of the transcription factor IRF1 underlies the distinct immune responses elicited by type I and type III interferons A Forero, S Ozarkar, H Li, CH Lee, EA Hemann, MS Nadjsombati, ... Immunity 51 (3), 451-464. e6, 2019 | 210 | 2019 |
Gasdermin D restrains type I interferon response to cytosolic DNA by disrupting ionic homeostasis I Banerjee, B Behl, M Mendonca, G Shrivastava, AJ Russo, A Menoret, ... Immunity 49 (3), 413-426. e5, 2018 | 205 | 2018 |
Novel functions of proteins encoded by viral stress-inducible genes SN Sarkar, GC Sen Pharmacology & therapeutics 103 (3), 245-259, 2004 | 197 | 2004 |
The interferon-stimulated genes: targets of direct signaling by interferons, double-stranded RNA, and viruses GC Sen, SN Sarkar Interferon: The 50th Anniversary, 233-250, 2007 | 193 | 2007 |
ATR kinase inhibitor AZD6738 potentiates CD8+ T cell–dependent antitumor activity following radiation FP Vendetti, P Karukonda, DA Clump, T Teo, R Lalonde, K Nugent, ... The Journal of clinical investigation 128 (9), 3926-3940, 2018 | 166 | 2018 |
Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity MR Hendricks, LP Lashua, DK Fischer, BA Flitter, KM Eichinger, ... Proceedings of the National Academy of Sciences 113 (6), 1642-1647, 2016 | 165 | 2016 |
Double-stranded RNA signaling by Toll-like receptor 3 requires specific tyrosine residues in its cytoplasmic domain SN Sarkar, HL Smith, TM Rowe, GC Sen Journal of Biological Chemistry 278 (7), 4393-4396, 2003 | 156 | 2003 |
Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin ML Antony, J Lee, ER Hahm, SH Kim, AI Marcus, V Kumari, X Ji, Z Yang, ... Journal of Biological Chemistry 289 (3), 1852-1865, 2014 | 120 | 2014 |
A specific isozyme of 2′-5′ oligoadenylate synthetase is a dual function proapoptotic protein of the Bcl-2 family A Ghosh, SN Sarkar, TM Rowe, GC Sen Journal of Biological Chemistry 276 (27), 25447-25455, 2001 | 117 | 2001 |
Oncolytic viruses engineered to enforce leptin expression reprogram tumor-infiltrating T cell metabolism and promote tumor clearance DB Rivadeneira, K DePeaux, Y Wang, A Kulkarni, T Tabib, AV Menk, ... Immunity 51 (3), 548-560. e4, 2019 | 113 | 2019 |
The nature of the catalytic domain of 2′-5′-oligoadenylate synthetases SN Sarkar, A Ghosh, HW Wang, SS Sung, GC Sen Journal of Biological Chemistry 274 (36), 25535-25542, 1999 | 108 | 1999 |
PKC alpha regulates Sendai virus‐mediated interferon induction through HDAC6 and β‐catenin J Zhu, CB Coyne, SN Sarkar The EMBO journal 30 (23), 4838-4849, 2011 | 106 | 2011 |
OASL—a new player in controlling antiviral innate immunity J Zhu, A Ghosh, SN Sarkar Current opinion in virology 12, 15-19, 2015 | 96 | 2015 |