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Shen Cheng
Shen Cheng
Verified email at umn.edu
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Nano-sized titanium dioxide-induced splenic toxicity: A biological pathway explored using microarray technology
L Sheng, L Wang, X Sang, X Zhao, J Hong, S Cheng, X Yu, D Liu, B Xu, ...
Journal of Hazardous Materials 278, 180-188, 2014
572014
Engineered mesenchymal stem cells for targeting solid tumors: therapeutic potential beyond regenerative therapy
S Cheng, SK Nethi, S Rathi, B Layek, S Prabha
Journal of Pharmacology and Experimental Therapeutics 370 (2), 231-241, 2019
562019
The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis
H Zhang, AL Yokom, S Cheng, M Su, PF Hollenberg, DR Southworth, ...
Journal of Biological Chemistry 293 (20), 7727-7736, 2018
442018
Phoxim‐induced damages of Bombyx mori larval midgut and titanium dioxide nanoparticles protective role under phoxim‐induced toxicity
J Su, B Li, S Cheng, Z Zhu, X Sang, S Gui, Y Xie, Q Sun, Z Cheng, ...
Environmental toxicology 29 (12), 1355-1366, 2014
352014
Pharmacokinetic—pharmacodynamic modeling of tumor targeted drug delivery using nano-engineered mesenchymal stem cells
S Cheng, SK Nethi, M Al-Kofahi, S Prabha
Pharmaceutics 13 (1), 92, 2021
112021
Pharmacokinetic Modeling of Warfarin І–Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug …
S Cheng, DR Flora, AE Rettie, RC Brundage, TS Tracy
Drug Metabolism and Disposition 50 (9), 1287-1301, 2022
82022
Pharmacokinetic Modeling of Warfarin ІI–Model-Based Analysis of Warfarin Metabolites after Warfarin Administered Either Alone or Together with Fluconazole or Rifampin
S Cheng, DR Flora, AE Rettie, RC Brundage, TS Tracy
Drug Metabolism and Disposition 50 (9), 1302-1311, 2022
52022
A physiological-based pharmacokinetic model embedded with a target-mediated drug disposition mechanism can characterize single-dose warfarin pharmacokinetic profiles in …
S Cheng, DR Flora, AE Rettie, RC Brundage, TS Tracy
Drug Metabolism and Disposition 51 (2), 257-267, 2023
32023
PBPK Model Development, Validation, and Application for Prediction of Eliglustat Drug‐Drug Interactions
SA Sahasrabudhe, S Cheng, M Al‐Kofahi, JR Jarnes, NJ Weinreb, ...
Clinical Pharmacology & Therapeutics, 2022
2*2022
Evaluation of bias in weighted residual calculations when handling below the limit of quantification data using Beal’s M3 method
MM Jaber, S Cheng, RC Brundage
CPT: Pharmacometrics & Systems Pharmacology 10 (4), 275, 2021
22021
Amphipol-facilitated elucidation of the functional tetrameric complex of full-length cytochrome P450 CYP2B4 and NADPH-cytochrome P450 oxidoreductase
S Cheng, Z Bo, P Hollenberg, Y Osawa, H Zhang
Journal of Biological Chemistry 296, 2021
22021
Population Pharmacokinetic Analysis of Atomoxetine and its Metabolites in Children and Adolescents with Attention‐Deficit/Hyperactivity Disorder
S Cheng, M Al‐Kofahi, JS Leeder, JT Brown
Clinical Pharmacology & Therapeutics 115 (5), 1033-1043, 2024
2024
POPULATION PHARMACOKINETICS OF ATOMOXETINE AND ITS METABOLITES IN CHILDREN AND ADOLESCENTS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD).
M Al-Kofahi, S Cheng, S Leeder, J Brown
CLINICAL PHARMACOLOGY & THERAPEUTICS 111, S10-S10, 2022
2022
Understanding the Impact of Pharmacogenetic Differences in Drug-Drug Interactions (DDIs): a Model-based Approach to Predict Differences in Drug Exposure
S Cheng
University of Minnesota, 2021
2021
Model-based analysis of the CYP2C9 genotype impact on the fluconazole inhibition of the commonly prescribed drugs flurbiprofen, ketoprofen, and tolbutamide
S Cheng, MM Jaber, DR Flora, TS Tracy, AE Rettie, RC Brundage
2021 American College of Clinical Pharmacology, 2021
2021
Genotype-Dependent Changes in Warfarin Clearance upon Co-administration of an Inhibitor (fluconazole) and an inducer (rifampin): A Model-based Analysis
S Cheng, DR Flora, TS Tracy, AE Rettie, RC Brundage
American Conference on Pharmacometrics 11 (ACoP11) 2 (ISSN:2688-3953), WED-071, 2020
2020
Synthetic antigen receptor mesenchymal stem cells (SAR-MSCs) targeting perlecan for drug delivery to ovarian cancer
SK Nethi, D Sehgal, S Cheng, J Panyam, S Prabha
Cancer Research 79 (13_Supplement), 2175-2175, 2019
2019
Elucidating the Disposition of Nano-engineered Mesenchymal Stem Cells using Pharmacokinetic Modeling
S Cheng, B Layek, M Al-Kofahi, RC Brundage, S Prabha
American Conference on Pharmacometrics 10 (ACoP10) 1 (ISSN:2688-3953), T-042, 2019
2019
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